Vern L. Schramm, Ph.D.
Affiliations: | Biochemistry | Albert Einstein College of Medicine, New York, New York, United States |
Area:
enzymatic mechanisms and transition state structureWebsite:
http://www.einstein.yu.edu/faculty/7856/vern-schramm/Google:
"Vern L. Schramm"Bio:
http://www.nasonline.org/member-directory/members/20005826.html
http://www.einstein.yu.edu/faculty/experts/7856/vern-schramm/
http://www.einstein.yu.edu/images/faculty/experts/profiles/54/schramm%20cv.pdf
Mean distance: 10.85 | S | N | B | C | P |
Parents
Sign in to add mentor| Robert P. Geyer | research assistant | 1963-1965 | Harvard | |
| (Masters Degree) | ||||
| John F. Morrison | grad student | 1968 | ANU | |
| (Kinetic studies of allosteric phosphotransferases) | ||||
| Lawrence I. Hochstein | post-doc | 1969-1971 | Ames Research Center | |
Children
Sign in to add trainee| Isabella Brew | research assistant | Albert Einstein | |
| Yong Zhang | grad student | 2006-2011 | Albert Einstein |
| Gabriel T Bedard | grad student | 2018-2026 | Albert Einstein |
| Ashleigh S Paparella | post-doc | Albert Einstein | |
| Phillip A. Schwartz | post-doc | Albert Einstein | |
| Andrew George Wagner | post-doc | Albert Einstein | |
| Zhen Wang | post-doc | 2013- | Albert Einstein |
| Nicole A. Horenstein | post-doc | 1989-1993 | Albert Einstein |
| Erika A. Taylor | post-doc | 2004-2007 | Albert Einstein |
| Andrew S. Murkin | post-doc | 2004-2009 | Albert Einstein |
| Rafael Guimaraes da Silva | post-doc | 2008-2012 | Albert Einstein |
| Mathew J. Vetticatt | post-doc | 2011-2013 | Albert Einstein |
| Roozbeh Eskandari | research scientist | 2022- | Albert Einstein |
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Publications
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| Minnow YVT, Schramm VL, Almo SC, et al. (2023) Phosphate Binding in PNP Alters Transition-State Analogue Affinity and Subunit Cooperativity. Biochemistry. 62: 3116-3125 |
| Brown M, Schramm VL. (2023) Decreased Transition-State Analogue Affinity in Isotopically Heavy MTAN with Increased Catalysis. Biochemistry |
| Mahmoodi N, Minnow YVT, Harijan RK, et al. (2023) Cell-Effective Transition-State Analogue of Phenylethanolamine -Methyltransferase. Biochemistry |
| Brown M, Tyler PC, Schramm VL. (2023) Residence Times for Femtomolar and Picomolar Inhibitors of MTANs. Biochemistry |
| Wagner AG, Eskandari R, Schramm VL. (2023) An enzyme-coupled microplate assay for activity and inhibition of hmdUMP hydrolysis by DNPH1. Analytical Biochemistry. 672: 115171 |
| V T Minnow Y, Suthagar K, Clinch K, et al. (2022) Inhibition and Mechanism of Hypoxanthine-Guanine-Xanthine Phosphoribosyltransferase. Acs Chemical Biology |
| Glockzin K, Kostomiris D, Minnow YVT, et al. (2022) Kinetic Characterization and Inhibition of Hypoxanthine-Guanine Phosphoribosyltransferases. Biochemistry. 61: 2088-2105 |
| Paparella AS, Cahill SM, Aboulache BL, et al. (2022) TcdB Toxin Glucosylates Rho GTPase by an S Mechanism and Ion Pair Transition State. Acs Chemical Biology. 17: 2507-2518 |
| Lamiable-Oulaidi F, Harijan RK, Shaffer KJ, et al. (2022) Synthesis and Characterization of Transition-State Analogue Inhibitors against Human DNA Methyltransferase 1. Journal of Medicinal Chemistry. 65: 5462-5494 |
| Paparella AS, Aboulache BL, Harijan RK, et al. (2021) Inhibition of Clostridium difficile TcdA and TcdB toxins with transition state analogues. Nature Communications. 12: 6285 |