Gary Parkinson
Affiliations: | 1998-2011 | School of Pharmacy | Institute of Cancer Research and University College London |
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Sign in to add mentor| Stephen Neidle | research scientist | 1998-2011 | Institute of Cancer Research and University College London |
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| Gao C, Liu Z, Hou H, et al. (2020) BMPQ-1 binds selectively to (3+1) hybrid topologies in human telomeric G-quadruplex multimers. Nucleic Acids Research |
| Mori M, Gilardoni E, Regazzoni L, et al. (2020) Towards the Inhibition of Protein-Protein Interactions (PPIs) in STAT3: Insights into a New Class of Benzothiadiazole Derivatives. Molecules (Basel, Switzerland). 25 |
| Zhang Y, El Omari K, Duman R, et al. (2020) Native de novo structural determinations of non-canonical nucleic acid motifs by X-ray crystallography at long wavelengths. Nucleic Acids Research |
| Parkinson GN, Collie GW. (2019) X-Ray Crystallographic Studies of G-Quadruplex Structures. Methods in Molecular Biology (Clifton, N.J.). 2035: 131-155 |
| Haider S, Li P, Khiali S, et al. (2018) Holliday Junctions Formed from Human Telomeric DNA. Journal of the American Chemical Society |
| Shih PC, Yang Y, Parkinson GN, et al. (2018) A high-throughput fluorescence polarization assay for discovering inhibitors targeting the DNA-binding domain of signal transducer and activator of transcription 3 (STAT3). Oncotarget. 9: 32690-32701 |
| Gunaratnam M, Collie GW, Reszka AP, et al. (2018) A naphthalene diimide G-quadruplex ligand inhibits cell growth and down-regulates BCL-2 expression in an imatinib-resistant gastrointestinal cancer cell line. Bioorganic & Medicinal Chemistry |
| Simone R, Balendra R, Moens TG, et al. (2017) G-quadruplex-binding small molecules ameliorate C9orf72 FTD/ALS pathology in vitro and in vivo. Embo Molecular Medicine |
| Noureini SK, Esmaeili H, Abachi F, et al. (2017) Selectivity of major isoquinoline alkaloids from Chelidomium majus towards telomeric G-quadruplex: A study using a modified transition-FRET (t-FRET) assay. Biochimica Et Biophysica Acta |
| Russo Krauss I, Ramaswamy S, Neidle S, et al. (2016) Structural Insights into the Quadruplex-Duplex 3' Interface formed from a Telomeric Repeat: A Potential Molecular Target. Journal of the American Chemical Society |