Charles Laughton
Affiliations: | 1990-1995 | CRC Biomolecular Structure Unit | The Institute of Cancer Research |
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Sign in to add mentor| Stephen Neidle | research scientist | 1990-1995 | The Institute of Cancer Research |
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Publications
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| da Rosa G, Grille L, Calzada V, et al. (2021) Sequence-dependent structural properties of B-DNA: what have we learned in 40 years? Biophysical Reviews. 13: 995-1005 |
| Di Pietro O, Juárez-Jiménez J, Muñoz-Torrero D, et al. (2017) Unveiling a novel transient druggable pocket in BACE-1 through molecular simulations: Conformational analysis and binding mode of multisite inhibitors. Plos One. 12: e0177683 |
| Sutthibutpong T, Matek C, Benham C, et al. (2016) Long-range correlations in the mechanics of small DNA circles under topological stress revealed by multi-scale simulation. Nucleic Acids Research |
| Pasi M, Maddocks JH, Beveridge D, et al. (2014) μABC: a systematic microsecond molecular dynamics study of tetranucleotide sequence effects in B-DNA. Nucleic Acids Research. 42: 12272-83 |
| Wang H, Cui J, Hong W, et al. (2013) The study of interactions between DNA and PcrA DNA helicase by using targeted molecular dynamic simulations. Journal of Molecular Modeling. 19: 4997-5006 |
| Garton M, Laughton C. (2013) A comprehensive model for the recognition of human telomeres by TRF1. Journal of Molecular Biology. 425: 2910-21 |
| Rannou O, Le Chatelier E, Larson MA, et al. (2013) Functional interplay of DnaE polymerase, DnaG primase and DnaC helicase within a ternary complex, and primase to polymerase hand-off during lagging strand DNA replication in Bacillus subtilis. Nucleic Acids Research. 41: 5303-20 |
| Islam B, Sgobba M, Laughton C, et al. (2013) Conformational dynamics of the human propeller telomeric DNA quadruplex on a microsecond time scale Nucleic Acids Research. 41: 2723-2735 |
| Wang H, Laughton CA. (2012) The inhibitory effects of vinylphosphonate-linked thymidine dimers on the unidirectional translocation of PcrA helicase along DNA: a molecular modelling study. Physical Chemistry Chemical Physics : Pccp. 14: 12230-7 |
| Girard PM, Laughton C, Nikjoo H. (2012) Determination of DNA structural detail using radioprobing. International Journal of Radiation Biology. 88: 123-8 |