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Joshua B. Sheetz, Ph.D.

Affiliations: 
2012-2015 Biochemistry & Biophysics University of North Carolina, Chapel Hill, Chapel Hill, NC 
 2015-2022 Pharmacology Yale University, New Haven, CT 
 2022- Molecular & Cell Biology University of California, Berkeley, Berkeley, CA, United States 
Area:
Cell Signaling
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Parents

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Henrik G. Dohlman research assistant 2012-2015 UNC Chapel Hill (Physics Tree)
Mark A. Lemmon grad student 2016-2022 Yale
Michael Rape post-doc 2022- UC Berkeley

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Publications

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Sheetz JB, Lemmon MA. (2022) Looking lively: emerging principles of pseudokinase signaling. Trends in Biochemical Sciences
Sheetz JB, Lemmon MA, Tsutsui Y. (2022) Dynamics of protein kinases and pseudokinases by HDX-MS. Methods in Enzymology. 667: 303-338
Shi F, Mendrola JM, Sheetz JB, et al. (2021) ROR and RYK extracellular region structures suggest that receptor tyrosine kinases have distinct WNT-recognition modes. Cell Reports. 37: 109834
Sheetz JB, Mathea S, Karvonen H, et al. (2020) Structural Insights into Pseudokinase Domains of Receptor Tyrosine Kinases. Molecular Cell
Gassaway BM, Cardone RL, Padyana AK, et al. (2019) Distinct Hepatic PKA and CDK Signaling Pathways Control Activity-Independent Pyruvate Kinase Phosphorylation and Hepatic Glucose Production. Cell Reports. 29: 3394-3404.e9
Rangarajan N, Gordy CL, Askew L, et al. (2019) Systematic analysis of F-box proteins reveals a new branch of the yeast mating pathway. The Journal of Biological Chemistry
Sheetz JB, Lemmon MA. (2018) Flipping ATP to AMPlify Kinase Functions. Cell. 175: 641-642
Gassaway BM, Petersen MC, Surovtseva YV, et al. (2018) PKCε contributes to lipid-induced insulin resistance through cross talk with p70S6K and through previously unknown regulators of insulin signaling. Proceedings of the National Academy of Sciences of the United States of America
Kelley JB, Dixit G, Sheetz JB, et al. (2015) RGS proteins and septins cooperate to promote chemotropism by regulating polar cap mobility. Current Biology : Cb. 25: 275-85
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