Hideaki Nagase
Affiliations: | Matrix Biology | Kennedy institute of Rheumatology |
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| Carreca AP, Pravatà VM, Markham M, et al. (2020) TIMP-3 facilitates binding of target metalloproteinases to the endocytic receptor LRP-1 and promotes scavenging of MMP-1. Scientific Reports. 10: 12067 |
| Schubert K, Collins LE, Green P, et al. (2019) LRP1 Controls TNF Release via the TIMP-3/ADAM17 Axis in Endotoxin-Activated Macrophages. Journal of Immunology (Baltimore, Md. : 1950) |
| Mekkat A, Poppleton E, An B, et al. (2018) Effects of flexibility of the α2 chain of type I collagen on collagenase cleavage. Journal of Structural Biology |
| Santamaria S, Nagase H. (2018) Measurement of Protease Activities Using Fluorogenic Substrates. Methods in Molecular Biology (Clifton, N.J.). 1731: 107-122 |
| Lund J, Elimar Bitsch AM, Grønbech Rasch M, et al. (2018) Monoclonal antibodies targeting the disintegrin-like domain of ADAMDEC1 modulates the proteolytic activity and enables quantification of ADAMDEC1 protein in human plasma. Mabs. 10: 118-128 |
| Yamamoto K, Scavenius C, Santamaria S, et al. (2018) Inhibition of LRP1 shedding reverses cartilage degradation in osteoarthritis Osteoarthritis and Cartilage. 26 |
| Duro-Castano A, Lim NH, Tranchant I, et al. (2018) In Vivo Imaging of MMP-13 Activity Using a Specific Polymer-FRET Peptide Conjugate Detects Early Osteoarthritis and Inhibitor Efficacy Advanced Functional Materials. 28: 1802738 |
| Chanalaris A, Doherty C, Marsden BD, et al. (2017) Suramin inhibits osteoarthritic cartilage degradation by increasing extracellular levels of chondroprotective tissue inhibitor of metalloproteinases 3 (TIMP-3). Molecular Pharmacology |
| Santamaria S, Fedorov O, McCafferty J, et al. (2017) Development of a monoclonal anti-ADAMTS-5 antibody that specifically blocks the interaction with LRP1. Mabs. 0 |
| Yamamoto K, Santamaria S, Botkjaer KA, et al. (2017) Inhibition of shedding of low-density lipoprotein receptor-related protein 1 reverses cartilage matrix degradation in osteoarthritis. Arthritis & Rheumatology (Hoboken, N.J.) |