Yongyuth Yuthavong
Affiliations: | 1969 | University of Oxford, Oxford, United Kingdom |
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Parents
Sign in to add mentor| Gordon Lowe | grad student | 1969 | Oxford | |
| (Investigation of the mechanism of action of papain) | ||||
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Publications
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| Decharuangsilp S, Arwon U, Hoarau M, et al. (2024) Flexible 2,4-diaminopyrimidine bearing a butyrolactone as Plasmodium falciparum dihydrofolate reductase inhibitors. Bioorganic Chemistry. 153: 107789 |
| Hoarau M, Sermmai P, Varatthan T, et al. (2023) Discovery of rigid biphenyl DHFR inhibitors using a fragment linking strategy. Rsc Medicinal Chemistry. 14: 1755-1766 |
| Vanichtanankul J, Yoomuang A, Taweechai S, et al. (2022) Structural Insight into Effective Inhibitors' Binding to Dihydrofolate Reductase Thymidylate Synthase. Acs Chemical Biology |
| Hoarau M, Suwanakitti N, Varatthan T, et al. (2022) Assay Development and Identification of the First 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase Inhibitors. Molecules (Basel, Switzerland). 27 |
| Posayapisit N, Pengon J, Prommana P, et al. (2021) Transgenic pyrimethamine-resistant plasmodium falciparum reveals transmission-blocking potency of P218, a novel antifolate candidate drug. International Journal For Parasitology |
| Kamchonwongpaisan S, Charoensetakul N, Srisuwannaket C, et al. (2020) Flexible diaminodihydrotriazine inhibitors of Plasmodium falciparum dihydrofolate reductase: Binding strengths, modes of binding and their antimalarial activities. European Journal of Medicinal Chemistry. 195: 112263 |
| Chitnumsub P, Jaruwat A, Talawanich Y, et al. (2020) The structure of Plasmodium falciparum hydroxymethyldihydropterin pyrophosphokinase-dihydropteroate synthase reveals the basis of sulfa resistance. The Febs Journal. 287: 3273-3297 |
| Saepua S, Sadorn K, Vanichtanankul J, et al. (2019) 6-Hydrophobic aromatic substituent pyrimethamine analogues as potential antimalarials for pyrimethamine-resistant Plasmodium falciparum. Bioorganic & Medicinal Chemistry. 27: 115158 |
| Jaruwat A, Riangrungroj P, Ubonprasert S, et al. (2019) Crystal structure of Plasmodium falciparum adenosine deaminase reveals a novel binding pocket for inosine. Archives of Biochemistry and Biophysics. 667: 6-13 |
| Tarnchompoo B, Chitnumsub P, Jaruwat A, et al. (2018) Hybrid Inhibitors of Malarial Dihydrofolate Reductase with Dual Binding Modes That Can Forestall Resistance. Acs Medicinal Chemistry Letters. 9: 1235-1240 |