Michael G. Fried, Ph.D.

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Fried MG, Melikishvili M. (2018) Quaternary Interactions and DNA Twist Modulate the Cooperative Binding of AGT Biophysical Journal. 114
Melikishvili M, Fried MG. (2017) Quaternary interactions and supercoiling modulate the cooperative DNA binding of AGT. Nucleic Acids Research
Chicka MC, Ren Q, Richards D, et al. (2016) Role of Munc13-4 as a Ca2+-dependent tether during platelet secretion. The Biochemical Journal. 473: 627-39
Melikishvili M, Fried MG. (2015) Resolving the contributions of two cooperative mechanisms to the DNA Binding of AGT. Biopolymers. 103: 509-16
Fried MG, Melikishvili M, Tessmer I. (2015) Cooperativity and Supercoiling Modulate Functions of Human O6-alkylguanine DNA Alkyltransferase Biophysical Journal. 108
Hellman LM, Spear TJ, Koontz CJ, et al. (2014) Repair of O6-methylguanine adducts in human telomeric G-quadruplex DNA by O6-alkylguanine-DNA alkyltransferase. Nucleic Acids Research. 42: 9781-91
Tessmer I, Fried MG. (2014) Insight into the cooperative DNA binding of the Oâ¶-alkylguanine DNA alkyltransferase. Dna Repair. 20: 14-22
Smith EC, Smith SE, Carter JR, et al. (2013) Trimeric transmembrane domain interactions in paramyxovirus fusion proteins: roles in protein folding, stability, and function. The Journal of Biological Chemistry. 288: 35726-35
Melikishvili M, Fried MG. (2012) Lesion-specific DNA-binding and repair activities of human Oâ¶-alkylguanine DNA alkyltransferase. Nucleic Acids Research. 40: 9060-72
Tessmer I, Melikishvili M, Fried MG. (2012) Cooperative cluster formation, DNA bending and base-flipping by O6-alkylguanine-DNA alkyltransferase. Nucleic Acids Research. 40: 8296-308