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Hiten Gutka

Affiliations: 
University of Illinois at Chicago, Chicago, IL, United States 
Area:
Pharmaceutical Biotechnology; Institute of Tuberculosis Research
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"Hiten Gutka"
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Gutka, Hiten J. Genetic Essentiality, Biochemical and Structural Properties of Fructose 1,6-bisphosphatases II thesis University of Illinois at Chicago (2013)

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Scott G. Franzblau grad student 2013 University of Illinois, Chicago
Farahnaz Movahedzadeh grad student 2013 University of Illinois, Chicago
 (Genetic Essentiality, Biochemical and Structural Properties of Fructose 1, 6-bisphosphatases II)

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Publications

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Selezneva AI, Harding LNM, Gutka HJ, et al. (2023) New structures of Class II Fructose-1,6-Bisphosphatase from Francisella tularensis provide a framework for a novel catalytic mechanism for the entire class. Plos One. 18: e0274723
Selezneva AI, Gutka HJ, Wolf NM, et al. (2020) Structural and biochemical characterization of the class II fructose-1,6-bisphosphatase from Francisella tularensis. Acta Crystallographica. Section F, Structural Biology Communications. 76: 524-535
Bondoc JMG, Gutka HJ, Almutairi MM, et al. (2020) Rv0100, a proposed acyl carrier protein in Mycobacterium tuberculosis: expression, purification and crystallization. Corrigendum. Acta Crystallographica. Section F, Structural Biology Communications. 76: 192-193
Bondoc JMG, Gutka HJ, Almutairi MM, et al. (2019) Rv0100, a proposed acyl carrier protein in Mycobacterium tuberculosis: expression, purification and crystallization. Acta Crystallographica. Section F, Structural Biology Communications. 75: 646-651
Wolf NM, Gutka HJ, Movahedzadeh F, et al. (2018) Structures of the Mycobacterium tuberculosis GlpX protein (class II fructose-1,6-bisphosphatase): implications for the active oligomeric state, catalytic mechanism and citrate inhibition. Acta Crystallographica. Section D, Structural Biology. 74: 321-331
Gutka HJ, Wolf NM, Bondoc JMG, et al. (2017) Enzymatic Characterization of Fructose 1,6-Bisphosphatase II from Francisella tularensis, an Essential Enzyme for Pathogenesis. Applied Biochemistry and Biotechnology
Gutka HJ, Wang Y, Franzblau SG, et al. (2015) glpx Gene in Mycobacterium tuberculosis Is Required for In Vitro Gluconeogenic Growth and In Vivo Survival. Plos One. 10: e0138436
Movahedzadeh F, Frita R, Gutka HJ. (2011) A two-step strategy for the complementation of M. tuberculosis mutants. Genetics and Molecular Biology. 34: 286-9
Gutka HJ, Franzblau SG, Movahedzadeh F, et al. (2011) Crystallization and preliminary X-ray characterization of the glpX-encoded class II fructose-1,6-bisphosphatase from Mycobacterium tuberculosis. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 67: 710-3
Gutka HJ, Rukseree K, Wheeler PR, et al. (2011) glpX gene of Mycobacterium tuberculosis: heterologous expression, purification, and enzymatic characterization of the encoded fructose 1,6-bisphosphatase II. Applied Biochemistry and Biotechnology. 164: 1376-89
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