Eric S Szymanski, Ph.D.

Affiliations: 
2014-2019 Biochemistry Duke University, Durham, NC 
Area:
Biochemisty, Nucleic Acids, Drug Discovery
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"Eric Szymanski"
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Publications

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Gu S, Szymanski ES, Rangadurai AK, et al. (2023) Dynamic basis for dA•dGTP and dA•d8OGTP misincorporation via Hoogsteen base pairs. Nature Chemical Biology
Lai LB, Lai SM, Szymanski ES, et al. (2022) Structural basis for impaired 5' processing of a mutant tRNA associated with defects in neuronal homeostasis. Proceedings of the National Academy of Sciences of the United States of America. 119: e2119529119
Gu S, Szymanski ES, Kaushik Rangadurai A, et al. (2021) The Dynamic Ensemble of A:G and A:8-Oxoguanine Mismatches in Duplex DNA: Implications for Replication Errors and Damage Repair Biophysical Journal. 120: 219a-220a
Rangadurai A, Szymanski ES, Kimsey I, et al. (2020) Probing conformational transitions towards mutagenic Watson-Crick-like G·T mismatches using off-resonance sugar carbon R relaxation dispersion. Journal of Biomolecular Nmr
Kaushik Rangadurai A, Szymanski ES, Shi H, et al. (2019) Watson-Crick Like Mismatches in Replication Fidelity Biophysical Journal. 116: 359a
Rangadurai A, Zhou H, Merriman DK, et al. (2018) Why are Hoogsteen base pairs energetically disfavored in A-RNA compared to B-DNA? Nucleic Acids Research
Kimsey IJ, Szymanski ES, Zahurancik WJ, et al. (2018) Dynamic basis for dG•dT misincorporation via tautomerization and ionization. Nature. 554: 195-201
Wear EE, Song J, Zynda G, et al. (2017) Genomic analysis of the DNA replication timing program during mitotic S phase in maize (Zea mays L.) root tips. The Plant Cell
Szymanski ES, Kimsey IJ, Al-Hashimi HM. (2017) Direct NMR Evidence that Transient Tautomeric and Anionic States in dG•dT Form Watson-Crick like Base Pairs. Journal of the American Chemical Society
Szymanski ES, Kimsey IJ, Al-Hashimi HM. (2017) Role of Watson-Crick-Like Mismatches in DNA Replication Fidelity Biophysical Journal. 112: 70a
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