Nicholas Proudfoot

Affiliations: 
Sir William Dunn School of Pathology University of Oxford, Oxford, United Kingdom 
Area:
mRNA processing, transcription termination
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"Nicholas Proudfoot"
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Parents

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George  G. Brownlee grad student MRC-LMB (Neurotree)
Tom Maniatis post-doc CSHL

Children

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Emma Whitelaw grad student Oxford (GenetiTree)
Mark Ashe grad student 1991-1997 Oxford
Hilary Ashe grad student 1992-1997 Oxford
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Publications

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Davidson L, Rouvière JO, Sousa-Luís R, et al. (2024) DNA-directed termination of mammalian RNA polymerase II. Genes & Development. 38: 998-1019
Larke MSC, Schwessinger R, Nojima T, et al. (2021) Enhancers predominantly regulate gene expression during differentiation via transcription initiation. Molecular Cell
Tan-Wong SM, Dhir S, Proudfoot NJ. (2019) R-Loops Promote Antisense Transcription across the Mammalian Genome. Molecular Cell. 76: 600-616.e6
Kamieniarz-Gdula K, Proudfoot NJ. (2019) Transcriptional Control by Premature Termination: A Forgotten Mechanism. Trends in Genetics : Tig. 35: 553-564
Kamieniarz-Gdula K, Gdula MR, Panser K, et al. (2019) Selective Roles of Vertebrate PCF11 in Premature and Full-Length Transcript Termination. Molecular Cell
Nojima T, Rebelo K, Gomes T, et al. (2018) RNA Polymerase II Phosphorylated on CTD Serine 5 Interacts with the Spliceosome during Co-transcriptional Splicing. Molecular Cell. 72: 369-379.e4
Volanakis A, Kamieniarz-Gdula K, Schlackow M, et al. (2017) WNK1 kinase and the termination factor PCF11 connect nuclear mRNA export with transcription. Genes & Development. 31: 2175-2185
Schlackow M, Nojima T, Gomes T, et al. (2016) Distinctive Patterns of Transcription and RNA Processing for Human lincRNAs. Molecular Cell
Proudfoot NJ. (2016) Transcriptional termination in mammals: Stopping the RNA polymerase II juggernaut. Science (New York, N.Y.). 352: aad9926
Nojima T, Gomes T, Carmo-Fonseca M, et al. (2016) Mammalian NET-seq analysis defines nascent RNA profiles and associated RNA processing genome-wide. Nature Protocols. 11: 413-28
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