Lan Guan, MD, PhD

Affiliations: 
2008- Cell Physiology and Molecular Biophysics Texas Tech University Health Sciences Center 
Area:
membrane transport and structure biology
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"Lan Guan"
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Publications

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Hariharan P, Guan L. (2024) Reconstitution of the Melibiose Permease of serovar Typhimurium (MelB) into Lipid Nanodiscs. Bio-Protocol. 14: e5045
Hariharan P, Bakhtiiari A, Liang R, et al. (2024) Distinct roles of the major binding residues in the cation-binding pocket of the melibiose transporter MelB. The Journal of Biological Chemistry. 300: 107427
Hariharan P, Bakhtiiari A, Liang R, et al. (2024) Distinct roles of the major binding residues in the cation-binding pocket of MelB. Biorxiv : the Preprint Server For Biology
Hariharan P, Shi Y, Katsube S, et al. (2024) Mobile barrier mechanisms for Na-coupled symport in an MFS sugar transporter. Elife. 12
Yoon S, Bae HE, Hariharan P, et al. (2024) Rational Approach to Improve Detergent Efficacy for Membrane Protein Stabilization. Bioconjugate Chemistry
Guan L. (2023) The rapid developments of membrane protein structure biology over the last two decades. Bmc Biology. 21: 300
Ghani L, Kim S, Ehsan M, et al. (2023) Melamine-cored glucosides for membrane protein solubilization and stabilization: importance of water-mediated intermolecular hydrogen bonding in detergent performance. Chemical Science. 14: 13014-13024
Hariharan P, Shi Y, Katsube S, et al. (2023) Mimicking the regulatory state of a major facilitator superfamily sugar transporter. Biorxiv : the Preprint Server For Biology
Blaimschein N, Parameswaran H, Nagler G, et al. (2023) The insertase YidC chaperones the polytopic membrane protein MelB inserting and folding simultaneously from both termini. Structure (London, England : 1993). 31: 1419-1430.e5
Katsube S, Willibal K, Vemulapally S, et al. (2023) In vivo and in vitro characterizations of melibiose permease (MelB) conformation- dependent nanobodies reveal sugar-binding mechanisms. The Journal of Biological Chemistry. 104967
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