Roberto Pellicciari
Affiliations: | Università di Perugia |
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Sign in to add trainee| Antimo Gioiello | research assistant | 2007-2014 | |
| Bruno Cerra | grad student | ||
| Antonio Macchiarulo | grad student | ||
| Antonio Macchiarulo | post-doc | ||
| Antimo Gioiello | post-doc | 2005-2007 | |
| Antonio Macchiarulo | research scientist | ||
| Marinella Roberti | research scientist | Università di Perugia |
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Publications
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| Ceccarelli G, Goracci L, Carotti A, et al. (2024) Discovery and Structure-Activity Relationships of Novel DAF-12 Receptor Modulators. Journal of Medicinal Chemistry |
| Rosatelli E, Carotti A, Cerra B, et al. (2023) Chemical exploration of TGR5 functional hot-spots: Synthesis and structure-activity relationships of C7- and C23-Substituted cholic acid derivatives. European Journal of Medicinal Chemistry. 261: 115851 |
| Cerra B, Venturoni F, Souma M, et al. (2022) Development of 3α,7α-dihydroxy-6α-ethyl-24-nor-5β-cholan-23-sulfate sodium salt (INT-767): Process optimization, synthesis and characterization of metabolites. European Journal of Medicinal Chemistry. 242: 114652 |
| Mancino V, Ceccarelli G, Carotti A, et al. (2021) Synthesis and biological activity of cyclopropyl Δ7-dafachronic acids as DAF-12 receptor ligands. Organic & Biomolecular Chemistry |
| Perino A, Velázquez-Villegas LA, Bresciani N, et al. (2021) Central anorexigenic actions of bile acids are mediated by TGR5. Nature Metabolism. 3: 595-603 |
| Dvorak Z, Klapholz M, Burris TP, et al. (2020) . Molecular Pharmacology |
| Sorrentino G, Perino A, Yildiz E, et al. (2020) Bile Acids Signal via TGR5 to Activate Intestinal Stem Cells and Epithelial Regeneration. Gastroenterology |
| Tomassi S, Pfahler J, Mautone N, et al. (2020) From PARP1 to TNKS2 Inhibition: A Structure-Based Approach. Acs Medicinal Chemistry Letters. 11: 862-868 |
| Bartolini D, De Franco F, Torquato P, et al. (2020) Garcinoic Acid Is a Natural and Selective Agonist of Pregnane X Receptor. Journal of Medicinal Chemistry |
| Bagnolini G, Milano D, Manerba M, et al. (2020) Synthetic lethality in pancreatic cancer: discovery of a new RAD51-BRCA2 small molecule disruptor that inhibits homologous recombination and synergizes with olaparib. Journal of Medicinal Chemistry |