Pavel Janscak

Affiliations: 
University of Zurich (UZH) 
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"Pavel Janscak"
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Isik E, Shukla K, Pospisilova M, et al. (2024) MutSβ-MutLβ-FANCJ axis mediates the restart of DNA replication after fork stalling at cotranscriptional G4/R-loops. Science Advances. 10: eadk2685
Martinikova AS, Stoyanov M, Oravetzova A, et al. (2023) PPM1D activity promotes the replication stress caused by cyclin E1 overexpression. Molecular Oncology
Andrs M, Stoy H, Boleslavska B, et al. (2023) Excessive reactive oxygen species induce transcription-dependent replication stress. Nature Communications. 14: 1791
Boleslavska B, Oravetzova A, Shukla K, et al. (2022) DDX17 helicase promotes resolution of R-loop-mediated transcription-replication conflicts in human cells. Nucleic Acids Research. 50: 12274-12290
Larsen BD, Benada J, Yung PYK, et al. (2022) Cancer cells use self-inflicted DNA breaks to evade growth limits imposed by genotoxic stress. Science (New York, N.Y.). 376: 476-483
Sakellariou D, Bak ST, Isik E, et al. (2022) MutSβ regulates G4-associated telomeric R-loops to maintain telomere integrity in ALT cancer cells. Cell Reports. 39: 110602
Nascakova Z, Boleslavska B, Urban V, et al. (2021) RAD51 Inhibition Induces R-Loop Formation in Early G1 Phase of the Cell Cycle. International Journal of Molecular Sciences. 22
Bauer M, Nascakova Z, Mihai AI, et al. (2020) The ALPK1/TIFA/NF-κB axis links a bacterial carcinogen to R-loop-induced replication stress. Nature Communications. 11: 5117
Andrs M, Hasanova Z, Oravetzova A, et al. (2020) RECQ5: A Mysterious Helicase at the Interface of DNA Replication and Transcription. Genes. 11
Chappidi N, Nascakova Z, Boleslavska B, et al. (2020) Fork Cleavage-Religation Cycle and Active Transcription Mediate Replication Restart after Fork Stalling at Co-transcriptional R-Loops. Molecular Cell. 77: 528-541.e8
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