Shailesh Natvarbhai Mistry
Affiliations: | University of Nottingham, Nottingham, England, United Kingdom |
Area:
GPCRs, medicinal chemistry, allosteric ligands, chemical biology toolsGoogle:
"Shailesh Mistry"Mean distance: (not calculated yet)
Parents
Sign in to add mentorStephen Hill | grad student | 2005-2008 | Nottingham |
Barrie Kellam | grad student | 2005-2008 | Nottingham |
Barrie Kellam | post-doc | 2008-2012 | Nottingham |
Peter Scammells | post-doc | 2012-2014 | Monash University |
Children
Sign in to add traineeSunil Rajput | grad student | 2013-2019 | Nottingham |
Timothy Fyfe | grad student | 2015-2019 | University of Nottingham/Monash University |
Emanuel Sousa | grad student | 2015-2020 | Nottingham |
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Publications
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Casella BM, Farmer JP, Nesheva DN, et al. (2023) Design, Synthesis, and Application of Fluorescent Ligands Targeting the Intracellular Allosteric Binding Site of the CXC Chemokine Receptor 2. Journal of Medicinal Chemistry |
Farmer JP, Mistry SN, Laughton CA, et al. (2022) Development of fluorescent peptide G protein-coupled receptor activation biosensors for NanoBRET characterization of intracellular allosteric modulators. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 36: e22576 |
Kok ZY, Stoddart LA, Mistry SJ, et al. (2022) Optimization of Peptide Linker-Based Fluorescent Ligands for the Histamine H Receptor. Journal of Medicinal Chemistry. 65: 8258-8288 |
Soukarieh F, Liu R, Romero M, et al. (2020) Hit Identification of New Potent PqsR Antagonists as Inhibitors of Quorum Sensing in Planktonic and Biofilm Grown . Frontiers in Chemistry. 8: 204 |
Mistry SN, Marchand P, Kellam B. (2019) 27th Annual GP2A Medicinal Chemistry Conference. Pharmaceuticals (Basel, Switzerland). 12 |
Fyfe TJ, Kellam B, Sykes DA, et al. (2019) Structure-Kinetic Profiling of Haloperidol Analogues at the Human Dopamine D Receptor. Journal of Medicinal Chemistry |
Fyfe TJ, Kellam B, Mistry SN, et al. (2019) Subtle modifications to a thieno[2,3-d]pyrimidine scaffold yield negative allosteric modulators and agonists of the dopamine D receptor. European Journal of Medicinal Chemistry. 168: 474-490 |
van der Westhuizen ET, Spathis A, Khajehali E, et al. (2018) Assessment of the Molecular Mechanisms of Action of Novel 4-Phenylpyridine-2-One and 6-Phenylpyrimidin-4-One Allosteric Modulators at the M Muscarinic Acetylcholine Receptors. Molecular Pharmacology. 94: 770-783 |
Fyfe TJ, Zarzycka B, Lim HD, et al. (2018) A Thieno[2,3-d]pyrimidine Scaffold is a Novel Negative Allosteric Modulator of the Dopamine D2 Receptor. Journal of Medicinal Chemistry |
Baker JG, Gardiner SM, Woolard J, et al. (2017) Novel selective β1-adrenoceptor antagonists for concomitant cardiovascular and respiratory disease. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology |