S. Harikrishna
Affiliations: | 2016 | Indian Institute of Technology Bombay, Mumbai, Maharashtra, India |
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Parents
Sign in to add mentorP. I. Pradeepkumar | grad student | 2016 | IIT Bombay |
Jens Meiler | post-doc | Vanderbilt |
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Publications
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Gangopadhyay S, Das G, Gupta S, et al. (2024) 4'--Acetamidomethyl-2'--methoxyethyl Nucleic Acid Modifications Improve Thermal Stability, Nuclease Resistance, Potency, and hAgo2 Binding of Small Interfering RNAs. The Journal of Organic Chemistry |
Sahoo A, Das G, Ghosh A, et al. (2024) N-Methyluridine and 2'-O-Alkyl/2'-Fluoro-N-methyluridine functionalized nucleic acids improve nuclease resistance while maintaining duplex geometry. Bioorganic & Medicinal Chemistry. 100: 117616 |
Das G, Harikrishna S, Gore KR. (2022) Influence of Sugar Modifications on the Nucleoside Conformation and Oligonucleotide Stability: A Critical Review. Chemical Record (New York, N.Y.). e202200174 |
Jana SK, Harikrishna S, Sudhakar S, et al. (2022) Nucleoside Analogues with a Seven-Membered Sugar Ring: Synthesis and Structural Compatibility in DNA-RNA Hybrids. The Journal of Organic Chemistry. 87: 2367-2379 |
Nikam RR, Harikrishna S, Gore KR. (2021) Synthesis, Structural, and Conformational Analysis of 4′‐ C ‐Alkyl‐2′‐ O ‐Ethyl‐Uridine Modified Nucleosides European Journal of Organic Chemistry. 2021: 924-932 |
Habibian M, Harikrishna S, Fakhoury J, et al. (2020) Effect of 2'-5'/3'-5' phosphodiester linkage heterogeneity on RNA interference. Nucleic Acids Research |
Harikrishna S, Kotaru S, Pradeepkumar PI. (2017) Ligand-induced conformational preorganization of loops of c-MYC G-quadruplex DNA and its implications in structure-specific drug design. Molecular Biosystems. 13: 1458-1468 |
Harikrishna S, Pradeepkumar PI. (2017) Probing the Binding Interactions between Chemically Modified siRNAs and Human Argonaute 2 Using Microsecond Molecular Dynamics Simulations. Journal of Chemical Information and Modeling. 57: 883-896 |
Diveshkumar KV, Sakrikar S, Rosu F, et al. (2016) Specific Stabilization of c-MYC and c-KIT G -Quadruplex DNA Structures by Indolylmethyleneindanone Scaffolds. Biochemistry |
Ghodke PP, Gore KR, Harikrishna S, et al. (2015) The N2-Furfuryl-Deoxyguanosine (fdG) Adduct Does Not Alter the Structure of B-DNA. The Journal of Organic Chemistry |