Sebastian Pomplun
Affiliations: | Massachusetts Institute of Technology, Cambridge, MA, United States |
Area:
Bioorganic chemistry, combinatorial drug discovery, chemical biology,Google:
"Sebastian Pomplun"Mean distance: (not calculated yet)
Parents
Sign in to add mentor| Felix Hausch | grad student | MPI Psychiatry Munich | |
| Brad L. Pentelute | post-doc | MIT |
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Publications
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| Ellenbroek BD, Kahler JP, Arella D, et al. (2024) Development of DuoMYC: a synthetic cell penetrant miniprotein that efficiently inhibits the oncogenic transcription factor MYC. Angewandte Chemie (International Ed. in English). e202416082 |
| Charalampidou A, Nehls T, Meyners C, et al. (2024) Automated Flow Peptide Synthesis Enables Engineering of Proteins with Stabilized Transient Binding Pockets. Acs Central Science. 10: 649-657 |
| Stransky F, Kostrz D, Follenfant M, et al. (2024) Use of DNA forceps to measure receptor-ligand dissociation equilibrium constants in a single-molecule competition assay. Methods in Enzymology. 694: 51-82 |
| Ellenbroek BD, Kahler JP, Evers SR, et al. (2024) Synthetic Peptides: Promising Modalities for the Targeting of Disease-Related Nucleic Acids. Angewandte Chemie (International Ed. in English). e202401704 |
| Kolos JM, Pomplun S, Jung S, et al. (2021) Picomolar FKBP inhibitors enabled by a single water-displacing methyl group in bicyclic [4.3.1] aza-amides. Chemical Science. 12: 14758-14765 |
| Pomplun S, Jbara M, Schissel CK, et al. (2021) Parallel Automated Flow Synthesis of Covalent Protein Complexes That Can Inhibit MYC-Driven Transcription. Acs Central Science. 7: 1408-1418 |
| Jbara M, Pomplun S, Schissel CK, et al. (2021) Engineering Bioactive Dimeric Transcription Factor Analogs via Palladium Rebound Reagents. Journal of the American Chemical Society |
| Pomplun S, Jbara M, Quartararo AJ, et al. (2021) Discovery of High-Affinity Peptide Binders for the SARS-CoV-2 Spike Protein. Acs Central Science. 7: 156-163 |
| Pomplun S. (2021) Targeting the SARS-CoV-2-spike protein: from antibodies to miniproteins and peptides Rsc Medicinal Chemistry. 12: 197-202 |
| Pomplun S. (2020) Targeting the SARS-CoV-2-spike protein: from antibodies to miniproteins and peptides. Rsc Medicinal Chemistry. 12: 197-202 |