Lydia Borgelt
Affiliations: | Max Planck Institute for Molecular Physiology |
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| Borgelt L, Hohnen L, Pallesen JS, et al. (2023) -Biphenyl Pyrrolinones and Dibenzofurans as RNA-Binding Protein LIN28 Inhibitors Disrupting the LIN28- Interaction. Acs Medicinal Chemistry Letters. 14: 1707-1715 |
| Borgelt L, Wu P. (2023) Targeting Ribonucleases with Small Molecules and Bifunctional Molecules. Acs Chemical Biology |
| Hommen P, Hwang J, Huang F, et al. (2023) Chromenopyrazole-peptide conjugates as small-molecule based inhibitors disrupting the protein-RNA interaction of LIN28-let-7. Chembiochem : a European Journal of Chemical Biology. e202300376 |
| Hwang J, Haacke N, Borgelt L, et al. (2023) Rational design and evaluation of 2-((pyrrol-2-yl)methylene)thiophen-4-ones as RNase L inhibitors. European Journal of Medicinal Chemistry. 256: 115439 |
| Borgelt L, Huang F, Hohnen L, et al. (2023) Spirocyclic Chromenopyrazole Inhibitors Disrupting the Interaction between the RNA-binding protein LIN28 and Let-7. Chembiochem : a European Journal of Chemical Biology. e202300168 |
| Borgelt L, Haacke N, Lampe P, et al. (2022) Small-molecule screening of ribonuclease L binders for RNA degradation. Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie. 154: 113589 |
| Hwang J, Qiu X, Borgelt L, et al. (2022) Synthesis and evaluation of RNase L-binding 2-aminothiophenes as anticancer agents. Bioorganic & Medicinal Chemistry. 58: 116653 |
| Goebel GL, Hohnen L, Borgelt L, et al. (2021) Small molecules with tetrahydroquinoline-containing Povarov scaffolds as inhibitors disrupting the Protein-RNA interaction of LIN28-let-7. European Journal of Medicinal Chemistry. 228: 114014 |
| Borgelt L, Li F, Hommen P, et al. (2021) Trisubstituted Pyrrolinones as Small-Molecule Inhibitors Disrupting the Protein-RNA Interaction of LIN28 and . Acs Medicinal Chemistry Letters. 12: 893-898 |
| Hwang J, Borgelt L, Wu P. (2020) Multicomponent Petasis Reaction for the Synthesis of Functionalized 2-Aminothiophenes and Thienodiazepines. Acs Combinatorial Science |