William Heggie

Affiliations: 
Hovione 
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"William Heggie"
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Viveiros R, Bonifácio VDB, Heggie W, et al. (2019) Green Development of Polymeric Dummy Artificial Receptors with Affinity for Amide-Based Pharmaceutical Impurities Acs Sustainable Chemistry & Engineering. 7: 15445-15451
Viveiros R, Dias FM, Maia LB, et al. (2017) Green strategy to produce large core–shell affinity beads for gravity-driven API purification processes Journal of Industrial and Engineering Chemistry. 54: 341-349
Viveiros R, Karim K, Piletsky SA, et al. (2017) Development of a molecularly imprinted polymer for a pharmaceutical impurity in supercritical CO2: Rational design using computational approach Journal of Cleaner Production. 168: 1025-1031
Viveiros R, Lopes MI, Heggie W, et al. (2017) Green approach on the development of lock-and-key polymers for API purification Chemical Engineering Journal. 308: 229-239
Esteves T, Viveiros R, Bandarra J, et al. (2016) Molecularly imprinted polymer strategies for removal of a genotoxic impurity, 4-dimethylaminopyridine, from an active pharmaceutical ingredient post-reaction stream Separation and Purification Technology. 163: 206-214
Szekely G, Amores de Sousa MC, Gil M, et al. (2015) Genotoxic Impurities in Pharmaceutical Manufacturing: Sources, Regulations, and Mitigation. Chemical Reviews. 115: 8182-229
Székely G, Gil M, Sellergren B, et al. (2013) Environmental and economic analysis for selection and engineering sustainable API degenotoxification processes Green Chemistry. 15: 210-225
Székely G, Fritz E, Bandarra J, et al. (2012) Removal of potentially genotoxic acetamide and arylsulfonate impurities from crude drugs by molecular imprinting. Journal of Chromatography. A. 1240: 52-8
Székely G, Bandarra J, Heggie W, et al. (2012) Design, preparation and characterization of novel molecularly imprinted polymers for removal of potentially genotoxic 1,3-diisopropylurea from API solutions Separation and Purification Technology. 86: 190-198
Székely G, Bandarra J, Heggie W, et al. (2012) A hybrid approach to reach stringent low genotoxic impurity contents in active pharmaceutical ingredients: Combining molecularly imprinted polymers and organic solvent nanofiltration for removal of 1,3-diisopropylurea Separation and Purification Technology. 86: 79-87
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