David A Griffith
Affiliations: | Pfizer, Cambridge, MA |
Area:
Medicinal ChemistryGoogle:
"David Griffith"Mean distance: (not calculated yet)
Parents
Sign in to add mentor| Samuel J. Danishefsky | grad student | 1987-1992 | Yale |
| Clayton H. Heathcock | post-doc | 1992-1995 | UC Berkeley |
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Publications
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| Limberakis C, Smith AC, Bagley SW, et al. (2023) Convergent Syntheses of Isomeric Imidazolospiroketones as Templates for Acetyl-CoA Carboxylase (ACC) Inhibitors. The Journal of Organic Chemistry |
| Bhattacharya SK, Aspnes GE, Bagley SW, et al. (2012) Identification of novel series of pyrazole and indole-urea based DFG-out PYK2 inhibitors. Bioorganic & Medicinal Chemistry Letters. 22: 7523-9 |
| Huard K, Bagley SW, Menhaji-Klotz E, et al. (2012) Synthesis of spiropiperidine lactam acetyl-CoA carboxylase inhibitors. The Journal of Organic Chemistry. 77: 10050-7 |
| Kalgutkar AS, Griffith DA, Ryder T, et al. (2010) Discovery tactics to mitigate toxicity risks due to reactive metabolite formation with 2-(2-hydroxyaryl)-5-(trifluoromethyl)pyrido[4,3-d]pyrimidin-4(3h)-one derivatives, potent calcium-sensing receptor antagonists and clinical candidate(s) for the treatment of osteoporosis. Chemical Research in Toxicology. 23: 1115-26 |
| Li J, Kung DW, Griffith DA. (2010) ChemInform Abstract: Synthesis of 5-Hydroxyquinolines. Cheminform. 41: no-no |
| DANISHEFSKY SJ, GERVAY J, PETERSON JM, et al. (2010) ChemInform Abstract: Application of Glycals to the Synthesis of Oligosaccharides: Convergent Total Syntheses of the Lewis X Trisaccharide Sialyl Lewis X Antigenic Determinant and Higher Congeners. Cheminform. 26: no-no |
| DANISHEFSKY SJ, KOSEKI K, GRIFFITH DA, et al. (2010) ChemInform Abstract: Azaglycosylation of Complex Stannyl Alkoxides with Glycal-Derived Iodo Sulfonamides: A Straightforward Synthesis of Sialyl-Lewis X Antigen and Other Oligosaccharide Domains. Cheminform. 24: no-no |
| DANISHEFSKY SJ, GERVAY J, PETERSON JM, et al. (2010) ChemInform Abstract: Remarkable Regioselectivity in the Chemical Glycosylation of Glycal Acceptors: A Concise Solution to the Synthesis of Sialyl-Lewis X Glycal. Cheminform. 24: no-no |
| GRIFFITH DA, DANISHEFSKY SJ. (2010) ChemInform Abstract: Total Synthesis of Allosamidin: An Application of the Sulfonamidoglycosylation of Glycals. Cheminform. 22: no-no |
| Didiuk MT, Griffith DA, Benbow JW, et al. (2009) Short-acting 5-(trifluoromethyl)pyrido[4,3-d]pyrimidin-4(3H)-one derivatives as orally-active calcium-sensing receptor antagonists. Bioorganic & Medicinal Chemistry Letters. 19: 4555-9 |