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Lei Chen

Affiliations: 
Peking University, Beijing, Beijing Shi, China 
Website:
https://scholar.google.com/citations?user=fOzkt2sAAAAJ&hl=en
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Parents

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Zhi-Xin Wang grad student Tsinghua Univeristy
Jiawei Wu grad student Tsinghua University, China
J. Eric Gouaux post-doc OHSU

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Publications

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Li K, Chen L, Lin Z, et al. (2020) Role of the AMPK/ACC Signaling Pathway in TRPP2-Mediated Head and Neck Cancer Cell Proliferation. Biomed Research International. 2020: 4375075
Thomas C, Aller SG, Beis K, et al. (2020) Structural and functional diversity calls for a new classification of ABC transporters. Febs Letters
Zhang Y, Liu S, Wang L, et al. (2016) A novel PI3K/AKT signaling axis mediates Nectin-4-induced gallbladder cancer cell proliferation, metastasis and tumor growth. Cancer Letters
Wu JX, Cheng YS, Wang J, et al. (2015) Structural insight into the mechanism of synergistic autoinhibition of SAD kinases. Nature Communications. 6: 8953
Wang J, Jiang J, Wang J, et al. (2014) Structural insights into the negative regulation of BRI1 signaling by BRI1-interacting protein BKI1. Cell Research. 24: 1328-41
Zheng LS, Liu YT, Chen L, et al. (2014) Structure and mechanism of the unique C2 domain of Aida. The Febs Journal. 281: 4622-32
Chen L, Xin FJ, Wang J, et al. (2013) Conserved regulatory elements in AMPK. Nature. 498: E8-10
Chen L, Wang J, Zhang YY, et al. (2012) AMP-activated protein kinase undergoes nucleotide-dependent conformational changes. Nature Structural & Molecular Biology. 19: 716-8
Zhu L, Chen L, Zhou XM, et al. (2011) Structural insights into the architecture and allostery of full-length AMP-activated protein kinase. Structure (London, England : 1993). 19: 515-22
Wang L, Liu YT, Hao R, et al. (2011) Molecular mechanism of the negative regulation of Smad1/5 protein by carboxyl terminus of Hsc70-interacting protein (CHIP). The Journal of Biological Chemistry. 286: 15883-94
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