Geoffrey L. Greene, PhD
Affiliations: | Ben May Department for Cancer Research | University of Chicago, Chicago, IL |
Area:
breast cancer, steroid hormone actionWebsite:
http://benmay.uchicago.edu/faculty/greeneGoogle:
"Geoffrey Greene"Mean distance: 8.77 | S | N | B | C | P |
Parents
Sign in to add mentor| Robert Lewis Letsinger | grad student | 1969-1974 | Northwestern | |
| (Synthesis of phosphoramidate analogs of oligonucleotides) | ||||
Children
Sign in to add trainee| Kendall W. Nettles | grad student | 2003 | Chicago |
| Ya-Ling Wu | grad student | 2005 | Chicago |
| Robert W. Hsieh | grad student | 2006 | Chicago |
| Erin E. O'Neill | grad student | 2007 | Chicago |
| Kerstin W. Sinkevicius | grad student | 2007 | Chicago |
| Ilana Berlin | grad student | 2009 | Chicago |
| Jessica Bockhorn | grad student | 2012 | Chicago |
| Thien Le | grad student | 2012 | Chicago |
| Adam J. Gasser | grad student | 2014 | Chicago |
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Publications
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| Porter BA, Frerich C, Lainé M, et al. (2023) Glucocorticoid Receptor Activation in Lobular Breast Cancer Is Associated with Reduced Cell Proliferation and Promotion of Metastases. Cancers. 15 |
| Huggins RJ, Hosfield D, Ishag-Osman A, et al. (2023) Evaluating steroid hormone receptor interactions using the live-cell NanoBRET proximity assay. Biorxiv : the Preprint Server For Biology |
| Ren P, Tiede C, Fanning SW, et al. (2022) Labeling of a Mutant Estrogen Receptor with an Affimer in a Breast Cancer Cell Line. Biophysical Journal |
| Hosfield DJ, Weber S, Li NS, et al. (2022) Stereospecific lasofoxifene derivatives reveal the interplay between estrogen receptor alpha stability and antagonistic activity in mutant breast cancer cells. Elife. 11 |
| Mayne CG, Toy W, Carlson KE, et al. (2021) Defining the Energetic Basis for a Conformational Switch Mediating Ligand-Independent Activation of Mutant Estrogen Receptors in Breast Cancer. Molecular Cancer Research : McR |
| Lainé M, Fanning SW, Chang YF, et al. (2021) Lasofoxifene as a potential treatment for therapy-resistant ER-positive metastatic breast cancer. Breast Cancer Research : Bcr. 23: 54 |
| Abderrahman B, Maximov PY, Curpan RF, et al. (2020) Rapid Induction of the Unfolded Protein Response and Apoptosis by Estrogen Mimic TTC-352 for the Treatment of Endocrine-Resistant Breast Cancer. Molecular Cancer Therapeutics |
| Maximov PY, Abderrahman B, Hawsawi YM, et al. (2020) The Structure-Function Relationship of Angular Estrogens and Estrogen Receptor Alpha to Initiate Estrogen-Induced Apoptosis in Breast Cancer Cells. Molecular Pharmacology |
| Kastrati I, Joosten SEP, Semina SE, et al. (2020) The NFκB pathway promotes tamoxifen tolerance and disease recurrence in estrogen receptor positive breast cancers. Molecular Cancer Research : McR |
| Fanning SW, Greene G, Conlan MG. (2020) X-ray crystal structure analysis of elacestrant (RAD1901), a novel selective estrogen receptor degrader (SERD), bound to estrogen receptor alpha ligand binding domain. Journal of Clinical Oncology. 38: e15647-e15647 |