Vijay Kumar Nuthakki
Affiliations: | 2019- | AcSIR-IIIM |
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| Kulkarni AS, Ramana SR, Nuthakki VK, et al. (2025) Silicon incorporated tacrine: design, synthesis, and evaluation of biological and pharmacokinetic parameters. Rsc Medicinal Chemistry |
| Reddy CN, Nuthakki VK, Sharma A, et al. (2024) Synthesis and Biological Evaluation of Colchicine─Aryl/Alkyl Amine Hybrids as Potential Noncytotoxic Cholinesterase Inhibitors: Identification of SBN-284 as a Dual Inhibitor of Cholinesterases and NLRP3 Inflammasome. Acs Chemical Neuroscience |
| Banoo R, Nuthakki VK, Wadje BN, et al. (2024) Design, synthesis, and pharmacological evaluation of indole-piperidine amides as Blood-brain barrier permeable dual cholinesterase and β-secretase inhibitors. European Journal of Medicinal Chemistry. 266: 116131 |
| Sharma M, Sharma A, Thakur S, et al. (2023) Discovery of blood-brain barrier permeable and orally bioavailable caffeine-based amide derivatives as acetylcholinesterase inhibitors. Bioorganic Chemistry. 139: 106719 |
| Abdullaha M, Banoo R, Nuthakki VK, et al. (2023) Methoxy-naphthyl-Linked -Benzyl Pyridinium Styryls as Dual Cholinesterase Inhibitors: Design, Synthesis, Biological Evaluation, and Structure-Activity Relationship. Acs Omega. 8: 17591-17608 |
| Nuthakki VK, Choudhary S, Reddy CN, et al. (2023) Design, Synthesis, and Pharmacological Evaluation of Embelin-Aryl/alkyl Amine Hybrids as Orally Bioavailable Blood-Brain Barrier Permeable Multitargeted Agents with Therapeutic Potential in Alzheimer's Disease: Discovery of SB-1448. Acs Chemical Neuroscience. 14: 1193-1219 |
| Sharma M, Sharma A, Nuthakki VK, et al. (2022) Design, synthesis, and structure-activity relationship of caffeine-based triazoles as dual AChE and BACE-1 inhibitors. Drug Development Research |
| Banoo R, Nuthakki VK, Abdullaha M, et al. (2022) Blood-brain barrier permeable benzylpiperidin-4-yl-linked benzylamino benzamides as dual cholinesterase inhibitors. Drug Development Research |
| Sharma A, Nuthakki VK, Gairola S, et al. (2022) A Coumarin-donepezil Hybrid as a Blood-brain Barrier Permeable Dual Cholinesterase Inhibitor: Isolation, Synthetic Modifications and Biological Evaluation of Natural Coumarins. Chemmedchem |
| Nuthakki VK, Mudududdla R, Bharate SB. (2021) Role of basic aminoalkyl chains in the lead optimization of Indoloquinoline alkaloids. European Journal of Medicinal Chemistry. 227: 113938 |