Steven S. Plotkin

Affiliations: 
Department of Physics and Astronomy University of British Columbia, Vancouver, Vancouver, BC, Canada 
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"Steven Plotkin"
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McAlary L, Nan JR, Shyu C, et al. (2024) Amyloidogenic regions in beta-strands II and III modulate the aggregation and toxicity of SOD1 in living cells. Open Biology. 14: 230418
Pokrishevsky E, DuVal MG, McAlary L, et al. (2024) Tryptophan residues in TDP-43 and SOD1 modulate the cross-seeding and toxicity of SOD1. The Journal of Biological Chemistry. 107207
Hsueh SCC, Nijland M, Aina A, et al. (2024) Cyclization Scaffolding for Improved Vaccine Immunogen Stability: Application to Tau Protein in Alzheimer's Disease. Journal of Chemical Information and Modeling. 64: 2035-2044
Garg P, Semmler S, Baudouin C, et al. (2022) Misfolding-Associated Exposure of Natively Buried Residues in Mutant SOD1 Facilitates Binding to TRAF6. Journal of Molecular Biology. 167697
Hsueh SCC, Nijland M, Peng X, et al. (2022) First Principles Calculation of Protein-Protein Dimer Affinities of ALS-Associated SOD1 Mutants. Frontiers in Molecular Biosciences. 9: 845013
Semmler S, Gagné M, Garg P, et al. (2020) TNF receptor associated factor 6 interacts with ALS-linked misfolded superoxide dismutase 1 and promotes aggregation. The Journal of Biological Chemistry
McAlary L, Plotkin SS, Yerbury JJ, et al. (2019) Prion-Like Propagation of Protein Misfolding and Aggregation in Amyotrophic Lateral Sclerosis. Frontiers in Molecular Neuroscience. 12: 262
Farrawell NE, Yerbury MR, Plotkin SS, et al. (2019) CuATSM Protects Against the In Vitro Cytotoxicity of Wild-Type-Like Copper-Zinc Superoxide Dismutase Mutants but not Mutants That Disrupt Metal Binding. Acs Chemical Neuroscience. 10: 1555-1564
Peng X, Cashman NR, Plotkin SS. (2018) Prediction of Misfolding-Specific Epitopes in SOD1 Using Collective Coordinates. The Journal of Physical Chemistry. B
Habibi M, Rottler J, Plotkin SS. (2017) The unfolding mechanism of monomeric mutant SOD1 by simulated force spectroscopy. Biochimica Et Biophysica Acta. Proteins and Proteomics. 1865: 1631-1642
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