Steven S. Plotkin
Affiliations: | Department of Physics and Astronomy | University of British Columbia, Vancouver, Vancouver, BC, Canada |
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Parents
Sign in to add mentorPeter G. Wolynes | grad student | Rice University | |
José Nelson Onuchic | post-doc | Rice University |
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Publications
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McAlary L, Nan JR, Shyu C, et al. (2024) Amyloidogenic regions in beta-strands II and III modulate the aggregation and toxicity of SOD1 in living cells. Open Biology. 14: 230418 |
Pokrishevsky E, DuVal MG, McAlary L, et al. (2024) Tryptophan residues in TDP-43 and SOD1 modulate the cross-seeding and toxicity of SOD1. The Journal of Biological Chemistry. 107207 |
Hsueh SCC, Nijland M, Aina A, et al. (2024) Cyclization Scaffolding for Improved Vaccine Immunogen Stability: Application to Tau Protein in Alzheimer's Disease. Journal of Chemical Information and Modeling. 64: 2035-2044 |
Garg P, Semmler S, Baudouin C, et al. (2022) Misfolding-Associated Exposure of Natively Buried Residues in Mutant SOD1 Facilitates Binding to TRAF6. Journal of Molecular Biology. 167697 |
Hsueh SCC, Nijland M, Peng X, et al. (2022) First Principles Calculation of Protein-Protein Dimer Affinities of ALS-Associated SOD1 Mutants. Frontiers in Molecular Biosciences. 9: 845013 |
Semmler S, Gagné M, Garg P, et al. (2020) TNF receptor associated factor 6 interacts with ALS-linked misfolded superoxide dismutase 1 and promotes aggregation. The Journal of Biological Chemistry |
McAlary L, Plotkin SS, Yerbury JJ, et al. (2019) Prion-Like Propagation of Protein Misfolding and Aggregation in Amyotrophic Lateral Sclerosis. Frontiers in Molecular Neuroscience. 12: 262 |
Farrawell NE, Yerbury MR, Plotkin SS, et al. (2019) CuATSM Protects Against the In Vitro Cytotoxicity of Wild-Type-Like Copper-Zinc Superoxide Dismutase Mutants but not Mutants That Disrupt Metal Binding. Acs Chemical Neuroscience. 10: 1555-1564 |
Peng X, Cashman NR, Plotkin SS. (2018) Prediction of Misfolding-Specific Epitopes in SOD1 Using Collective Coordinates. The Journal of Physical Chemistry. B |
Habibi M, Rottler J, Plotkin SS. (2017) The unfolding mechanism of monomeric mutant SOD1 by simulated force spectroscopy. Biochimica Et Biophysica Acta. Proteins and Proteomics. 1865: 1631-1642 |