Peter R. David, Ph.D.
Affiliations: | BioDTX |
Area:
Novel Pharmaceuticals, data analytics,Website:
http://www.biodtx.comGoogle:
"Peter David"Bio:
Peter David did his doctorate with William N. Lipscomb at Harvard, where he determined the de novo structure of the first leucine amino peptidase. He then did postdoctoral work with Michael Levitt at Stanford writing computer software to design drugs automatically. A subsequent company of his has the first completely computer designed drug on the market. Peter then lead the crystallography team that did the atomic structures of yeast RNA polymerase II.
Mean distance: 7.36
Parents
Sign in to add mentorWilliam N. Lipscomb | grad student | 1984-1990 | Harvard |
Michael Levitt | post-doc | 1991-1993 | Stanford |
Collaborators
Sign in to add collaboratorRoger D. Kornberg | collaborator | 1993-1998 | Stanford Medical School |
BETA: Related publications
See more...
Publications
You can help our author matching system! If you notice any publications incorrectly attributed to this author, please sign in and mark matches as correct or incorrect. |
Cramer P, Bushnell DA, Fu J, et al. (2000) Architecture of RNA polymerase II and implications for the transcription mechanism. Science (New York, N.Y.). 288: 640-9 |
Fu J, Gnatt AL, Bushnell DA, et al. (1999) Yeast RNA polymerase II at 5 A resolution. Cell. 98: 799-810 |
Fu J, Gerstein M, David PR, et al. (1998) Repeated tertiary fold of RNA polymerase II and implications for DNA binding. Journal of Molecular Biology. 280: 317-22 |
Edwards AM, Darst SA, Hemming SA, et al. (1997) [11] Two-dimensional protein crystals in aid of three-dimensional protein crystal growth. Methods in Enzymology. 276: 166-171 |
Edwards AM, Darst SA, Hemming SA, et al. (1997) Two-dimensional protein crystals in aid of three-dimensional protein crystal growth Methods in Enzymology. 276: 166-171 |
David PR, Bushnell DA, Leuther KK, et al. (1996) Low-resolutionab initioenvelopes of yeast RNA polymerase II Acta Crystallographica Section a Foundations of Crystallography. 52: C65-C65 |
Burley SK, David PR, Sweet RM, et al. (1992) Structure determination and refinement of bovine lens leucine aminopeptidase and its complex with bestatin. Journal of Molecular Biology. 224: 113-40 |
Burley SK, David PR, Lipscomb WN. (1991) Leucine aminopeptidase: bestatin inhibition and a model for enzyme-catalyzed peptide hydrolysis. Proceedings of the National Academy of Sciences of the United States of America. 88: 6916-20 |
David PR, Burley SK. (1991) Method for equilibrating protein crystals with heavy-atom reagents Journal of Applied Crystallography. 24: 1073-1074 |
Burley SK, David PR, Taylor A, et al. (1990) Molecular structure of leucine aminopeptidase at 2.7-A resolution. Proceedings of the National Academy of Sciences of the United States of America. 87: 6878-82 |