Farhang Alem
Affiliations: | School of Systems Biology | George Mason University, Washington, DC |
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Publications
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| Adhikari RP, Alem F, Kemboi D, et al. (2024) Engineered antibodies targeted to bacterial surface integrate effector functions with toxin neutralization to provide superior efficacy against bacterial infections. Medrxiv : the Preprint Server For Health Sciences |
| Alem F, Brahms A, Tarasaki K, et al. (2024) HSP90 is part of a protein complex with the L polymerase of Rift Valley fever phlebovirus and prevents its degradation by the proteasome during the viral genome replication/transcription stage. Frontiers in Cellular and Infection Microbiology. 14: 1331755 |
| Faley SL, Boghdeh NA, Schaffer DK, et al. (2024) Gravity-perfused airway-on-a-chip optimized for quantitative BSL-3 studies of SARS-CoV-2 infection: barrier permeability, cytokine production, immunohistochemistry, and viral load assays. Lab On a Chip |
| Anderson CA, Barrera MD, Boghdeh NA, et al. (2023) Brilacidin as a Broad-Spectrum Inhibitor of Enveloped, Acutely Infectious Viruses. Microorganisms. 12 |
| Saul S, Karim M, Ghita L, et al. (2023) Anticancer pan-ErbB inhibitors reduce inflammation and tissue injury and exert broad-spectrum antiviral effects. The Journal of Clinical Investigation |
| Anderson C, Baha H, Boghdeh N, et al. (2023) Interactions of Equine Viruses with the Host Kinase Machinery and Implications for One Health and Human Disease. Viruses. 15 |
| Boghdeh NA, McGraw B, Barrera MD, et al. (2023) Inhibitors of the Ubiquitin-Mediated Signaling Pathway Exhibit Broad-Spectrum Antiviral Activities against New World Alphaviruses. Viruses. 15 |
| Boghdeh NA, Risner KH, Barrera MD, et al. (2022) Application of a Human Blood Brain Barrier Organ-on-a-Chip Model to Evaluate Small Molecule Effectiveness against Venezuelan Equine Encephalitis Virus. Viruses. 14 |
| Haikerwal A, Barrera MD, Bhalla N, et al. (2022) Inhibition of Venezuelan Equine Encephalitis Virus Using Small Interfering RNAs. Viruses. 14 |
| Hetrick B, Chilin LD, He S, et al. (2022) Development of a hybrid alphavirus-SARS-CoV-2 pseudovirion for rapid quantification of neutralization antibodies and antiviral drugs. Cell Reports Methods. 100181 |