Manfred Philipp
Affiliations: | Lehman College & Graduate Center, CUNY |
Area:
serine hydrolases, boronic acids, enzyme inhibitors, bioinformaticsGoogle:
"Manfred Philipp"Mean distance: (not calculated yet)
Parents
Sign in to add mentor| Myron L. Bender | grad student | 1966-1971 | Northwestern |
| Hartmut Seliger | post-doc | 1971-1975 | University of Freiburg, Germany |
Children
Sign in to add trainee| Cristina C. Clement | grad student | 1999-2006 | City University of New York (CUNY) Graduate Center |
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Publications
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| Yang SY, He XY, Isaacs C, et al. (2014) Roles of 17β-hydroxysteroid dehydrogenase type 10 in neurodegenerative disorders. The Journal of Steroid Biochemistry and Molecular Biology. 143: 460-72 |
| Yang SY, Dobkin C, He XY, et al. (2013) A 5-methylcytosine hotspot responsible for the prevalent HSD17B10 mutation. Gene. 515: 380-4 |
| Figueiredo AC, Clement CC, Zakia S, et al. (2012) Rational design and characterization of D-Phe-Pro-D-Arg-derived direct thrombin inhibitors. Plos One. 7: e34354 |
| Seaver LH, He XY, Abe K, et al. (2011) A novel mutation in the HSD17B10 gene of a 10-year-old boy with refractory epilepsy, choreoathetosis and learning disability. Plos One. 6: e27348 |
| Carvalho Figueiredo A, Clement CC, Philipp M, et al. (2011) Crystallization and preliminary crystallographic characterization of three peptidic inhibitors in complex with α-thrombin. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 67: 54-8 |
| Yang SY, He XY, Olpin SE, et al. (2009) Mental retardation linked to mutations in the HSD17B10 gene interfering with neurosteroid and isoleucine metabolism. Proceedings of the National Academy of Sciences of the United States of America. 106: 14820-4 |
| Clement CC, Babinska A, Kornecki E, et al. (2009) Isothermal titration calorimetry and inhibition of platelets aggregation by [D-Phe/(transcinnamoyl)-Pro-D-Arg-P1'-CONH2] peptides inhibitors of thrombin. Advances in Experimental Medicine and Biology. 611: 579-80 |