William C. Merrick

Affiliations: 
Biochemistry Case Western Reserve University, Cleveland Heights, OH, United States 
Area:
eukaryotic translation initiation factors, initiation pathway
Website:
http://www.case.edu/med/biochemistry/faculty/merrick.html
Google:
"William Chaplin Merrick"
Mean distance: 11.73
 
SNBCP

Parents

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Leon Sebring Dure III grad student 1971 University of Georgia
 (Changes in isoaccepting tRNA species during germination of cotton seeds)
French Anderson post-doc NIH (Cell & Gene Therapy Tree)

Children

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Thomas E. Dever grad student 1990 Case Western
Lucas C. Reineke grad student 2009 Case Western
Thomas Sweet grad student 2011 Case Western
Yasaman Jaladat grad student 2012 Case Western
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Publications

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Krokowski D, Jobava R, Szkop KJ, et al. (2022) Stress-induced perturbations in intracellular amino acids reprogram mRNA translation in osmoadaptation independently of the ISR. Cell Reports. 40: 111092
Lyons SM, Kharel P, Akiyama Y, et al. (2020) eIF4G has intrinsic G-quadruplex binding activity that is required for tiRNA function. Nucleic Acids Research
Komar AA, Merrick WC. (2020) A Retrospective on eIF2A-and Not the Alpha Subunit of eIF2. International Journal of Molecular Sciences. 21
Chu J, Zhang W, Cencic R, et al. (2020) Rocaglates Induce Gain-of-Function Alterations to eIF4A and eIF4F. Cell Reports
Merrick WC, Pavitt GD. (2018) Protein Synthesis Initiation in Eukaryotic Cells. Cold Spring Harbor Perspectives in Biology
Guan BJ, van Hoef V, Jobava R, et al. (2017) A Unique ISR Program Determines Cellular Responses to Chronic Stress. Molecular Cell. 68: 885-900.e6
Golovko A, Kojukhov A, Guan BJ, et al. (2016) The eIF2A knockout mouse. Cell Cycle (Georgetown, Tex.). 0
Carelli JD, Sethofer SG, Smith GA, et al. (2015) Ternatin and improved synthetic variants kill cancer cells by targeting the elongation factor-1A ternary complex. Elife. 4
Merrick WC. (2015) eIF4F: A Retrospective. The Journal of Biological Chemistry. 290: 24091-9
Chen H, Song R, Wang G, et al. (2015) OLA1 regulates protein synthesis and integrated stress response by inhibiting eIF2 ternary complex formation. Scientific Reports. 5: 13241
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