William C. Merrick
Affiliations: | Biochemistry | Case Western Reserve University, Cleveland Heights, OH, United States |
Area:
eukaryotic translation initiation factors, initiation pathwayWebsite:
http://www.case.edu/med/biochemistry/faculty/merrick.htmlGoogle:
"William Chaplin Merrick"Mean distance: 11.73 | S | N | B | C | P |
Parents
Sign in to add mentorLeon Sebring Dure III | grad student | 1971 | University of Georgia | |
(Changes in isoaccepting tRNA species during germination of cotton seeds) | ||||
French Anderson | post-doc | NIH (Cell & Gene Therapy Tree) |
Children
Sign in to add traineeThomas E. Dever | grad student | 1990 | Case Western |
Lucas C. Reineke | grad student | 2009 | Case Western |
Thomas Sweet | grad student | 2011 | Case Western |
Yasaman Jaladat | grad student | 2012 | Case Western |
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Publications
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Krokowski D, Jobava R, Szkop KJ, et al. (2022) Stress-induced perturbations in intracellular amino acids reprogram mRNA translation in osmoadaptation independently of the ISR. Cell Reports. 40: 111092 |
Lyons SM, Kharel P, Akiyama Y, et al. (2020) eIF4G has intrinsic G-quadruplex binding activity that is required for tiRNA function. Nucleic Acids Research |
Komar AA, Merrick WC. (2020) A Retrospective on eIF2A-and Not the Alpha Subunit of eIF2. International Journal of Molecular Sciences. 21 |
Chu J, Zhang W, Cencic R, et al. (2020) Rocaglates Induce Gain-of-Function Alterations to eIF4A and eIF4F. Cell Reports |
Merrick WC, Pavitt GD. (2018) Protein Synthesis Initiation in Eukaryotic Cells. Cold Spring Harbor Perspectives in Biology |
Guan BJ, van Hoef V, Jobava R, et al. (2017) A Unique ISR Program Determines Cellular Responses to Chronic Stress. Molecular Cell. 68: 885-900.e6 |
Golovko A, Kojukhov A, Guan BJ, et al. (2016) The eIF2A knockout mouse. Cell Cycle (Georgetown, Tex.). 0 |
Carelli JD, Sethofer SG, Smith GA, et al. (2015) Ternatin and improved synthetic variants kill cancer cells by targeting the elongation factor-1A ternary complex. Elife. 4 |
Merrick WC. (2015) eIF4F: A Retrospective. The Journal of Biological Chemistry. 290: 24091-9 |
Chen H, Song R, Wang G, et al. (2015) OLA1 regulates protein synthesis and integrated stress response by inhibiting eIF2 ternary complex formation. Scientific Reports. 5: 13241 |