Ben Shen, Ph.D.

Affiliations: 
Chemistry Scripps Research Institute, La Jolla, La Jolla, CA, United States 
Area:
Natural Product Biosynthesis
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"Ben Shen"
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Publications

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Jalali E, Wang F, Overbay BR, et al. (2024) Biochemical and Structural Studies of the Carminomycin 4--Methyltransferase DnrK. Journal of Natural Products
Steele AD, Jiang H, Pan G, et al. (2024) Discrete Acyltransferases and Thioesterases in Iso-Migrastatin and Lactimidomycin Biosynthesis. Biochemistry
Fluegel LL, Deng MR, Su P, et al. (2024) Development of platensimycin, platencin, and platensilin overproducers by biosynthetic pathway engineering and fermentation medium optimization. Journal of Industrial Microbiology & Biotechnology
Bhardwaj M, Cui Z, Daniel Hankore E, et al. (2023) A discrete intermediate for the biosynthesis of both the enediyne core and the anthraquinone moiety of enediyne natural products. Proceedings of the National Academy of Sciences of the United States of America. 120: e2220468120
Meng S, Steele AD, Yan W, et al. (2021) Thiocysteine lyases as polyketide synthase domains installing hydropersulfide into natural products and a hydropersulfide methyltransferase. Nature Communications. 12: 5672
Luo J, Yang D, Hindra, et al. (2021) Discovery of ammosesters by mining the Streptomyces uncialis DCA2648 genome revealing new insight into ammosamide biosynthesis. Journal of Industrial Microbiology & Biotechnology
Cao M, Zheng C, Yang D, et al. (2021) Cryptic sulfur incorporation in thioangucycline biosynthesis. Angewandte Chemie (International Ed. in English)
Zheng CJ, Kalkreuter E, Fan BY, et al. (2020) PtmC Catalyzes the Final Step of Thioplatensimycin, Thioplatencin, and Thioplatensilin Biosynthesis and Expands the Scope of Arylamine -Acetyltransferases. Acs Chemical Biology
Lohman JR, Shen B. (2020) The LnmK Bifunctional Acyltransferase/Decarboxylase Specifying (2)-Methylmalonyl-CoA and Employing Substrate-Assisted Catalysis for Polyketide Biosynthesis. Biochemistry
Zhang X, King-Smith E, Dong LB, et al. (2020) Divergent synthesis of complex diterpenes through a hybrid oxidative approach. Science (New York, N.Y.). 369: 799-806
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