Karen L. Lang
Affiliations: | 2008-2012 | Centro de Ciências da Saúde - CCS | Universidade Federal de Santa Catarina (UFSC), Brazil |
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Parents
Sign in to add mentor| Fernando Duran | grad student | 2008-2012 | Universidade Federal de Santa Catarina (UFSC), Brazil |
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| Marostica LL, de Barros ALB, Oliveira J, et al. (2017) Antitumor effectiveness of a combined therapy with a new cucurbitacin B derivative and paclitaxel on a human lung cancer xenograft model. Toxicology and Applied Pharmacology |
| Silva IT, Geller FC, Persich L, et al. (2016) Cytotoxic effects of natural and semisynthetic cucurbitacins on lung cancer cell line A549. Investigational New Drugs. 34: 139-48 |
| Marostica LL, Silva IT, Kratz JM, et al. (2015) Synergistic Antiproliferative Effects of a New Cucurbitacin B Derivative and Chemotherapy Drugs on Lung Cancer Cell Line A549. Chemical Research in Toxicology. 28: 1949-60 |
| Silva IT, Carvalho A, Lang KL, et al. (2015) In vitro and in vivo antitumor activity of a novel semisynthetic derivative of cucurbitacin B. Plos One. 10: e0117794 |
| Lang KL, Silva IT, Machado VR, et al. (2014) Multivariate SAR and QSAR of cucurbitacin derivatives as cytotoxic compounds in a human lung adenocarcinoma cell line. Journal of Molecular Graphics & Modelling. 48: 70-9 |
| Lang KL, Deagosto E, Zimmermann LA, et al. (2013) Chemical modification produces species-specific changes in cucurbitacin antifeedant effect. Journal of Agricultural and Food Chemistry. 61: 5534-9 |
| Lang KL, Silva IT, Zimmermann LA, et al. (2012) Cytotoxic activity of semi-synthetic derivatives of elatol and isoobtusol. Marine Drugs. 10: 2254-64 |
| Lang KL, Silva IT, Zimmermann LA, et al. (2012) Synthesis and cytotoxic activity evaluation of dihydrocucurbitacin B and cucurbitacin B derivatives. Bioorganic & Medicinal Chemistry. 20: 3016-30 |
| Lang KL, da Rosa Guimarães T, Rocha Machado V, et al. (2011) New cytotoxic cucurbitacins from Wilbrandia ebracteata Cogn. Planta Medica. 77: 1648-51 |