☰ Chemistry Tree

David Lee Smith

Affiliations:	1974-1984	Chemistry	University of Utah, Salt Lake City, UT
	1984-1994	Medicinal Chemistry	Purdue University, West Lafayette, IN, United States
	1994-2004	Chemistry	The University of Nebraska - Lincoln, Lincoln, NE

Area:

Physical chemistry, analytical chemistry, mass spectrometry, hydrogen exchange

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Mean distance: 9.24

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Parents

Larry James Kevan	grad student	1966-1969	University of Kansas
Jean H. Futrell	post-doc	1969-1974	University of Utah
James A. McCloskey	research scientist	1974-1984	University of Utah

Children

John R. Engen	grad student	1995-1999	University of Nebraska - Lincoln
Jiwen Chen	grad student	2000	University of Nebraska - Lincoln
Hai Pan	grad student	2002	University of Nebraska - Lincoln
Lintao Wang	grad student	2002	University of Nebraska - Lincoln
Catherine M. Swaim	grad student	2003	University of Nebraska - Lincoln
Xiaoyan Cheng	grad student	2009	University of Nebraska - Lincoln
Jurgen Sidgman	grad student	2009	University of Nebraska - Lincoln
Mariah Webinger	grad student	2009	University of Nebraska - Lincoln

Collaborators

BETA: Related publications

Publications

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Chen J, Concel VJ, Bhatla S, et al. (2007) Alternative splicing of an rnp-4f mRNA isoform retaining an evolutionarily-conserved 5'-UTR intronic element is developmentally regulated and shown via RNAi to be essential for normal central nervous system development in Drosophila melanogaster. Gene. 399: 91-104
Wang L, Smith DL. (2005) Capsid structure and dynamics of a human rhinovirus probed by hydrogen exchange mass spectrometry. Protein Science : a Publication of the Protein Society. 14: 1661-72
Pan H, Smith DL. (2004) Amide hydrogen exchange/mass spectrometry applied to cooperative protein folding: equilibrium unfolding of Staphylococcus aureus aldolase. Methods in Enzymology. 380: 285-308
Pan H, Raza AS, Smith DL. (2004) Equilibrium and kinetic folding of rabbit muscle triosephosphate isomerase by hydrogen exchange mass spectrometry. Journal of Molecular Biology. 336: 1251-63
Pan H, Smith DL. (2003) Quaternary structure of aldolase leads to differences in its folding and unfolding intermediates. Biochemistry. 42: 5713-21
Wang L, Smith DL. (2003) Downsizing improves sensitivity 100-fold for hydrogen exchange-mass spectrometry. Analytical Biochemistry. 314: 46-53
Wang L, Smith DL. (2002) Probing protein structure and dynamics by hydrogen exchange-mass spectrometry. Current Protocols in Protein Science / Editorial Board, John E. Coligan ... [Et Al.]. Unit 17.6
Wang L, Pan H, Smith DL. (2002) Hydrogen exchange-mass spectrometry: optimization of digestion conditions. Molecular & Cellular Proteomics : McP. 1: 132-8
Gmeiner WH, Xu I, Horita DA, et al. (2001) Intramolecular binding of a proximal PPII helix to an SH3 domain in the fusion protein SH3Hck : PPIIhGAP. Cell Biochemistry and Biophysics. 35: 115-26
Chen J, Walter S, Horwich AL, et al. (2001) Folding of malate dehydrogenase inside the GroEL-GroES cavity. Nature Structural Biology. 8: 721-8

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