Stephen S. Hecht
Affiliations: | 1996- | Pharmacy | University of Minnesota, Twin Cities, Minneapolis, MN |
Area:
mechanisms of chemical carcinogenesis in humans, including those related to tobacco-induced cancerWebsite:
http://www.pharmacy.umn.edu/faculty/hecht_stephen/Google:
"Stephen Samuel Hecht"Bio:
http://www.cancer.gov/research/nci-role/spotlight/merit/hecht
http://www.acs.org/content/acs/en/pressroom/newsreleases/2012/july/stephen-s-hecht-phd-named-new-editor-in-chief-of-chemical-research-in-toxicology.html
http://www.acschemtox.org/inside/Pages/newsletter_03-09.aspx
DOI: 10.1021/ar50135a003
Mean distance: 7.46
Parents
Sign in to add mentorArthur C. Cope | grad student | 1966 | MIT | |
Frederick Davis Greene | grad student | 1968 | MIT | |
(Part I: Aprotic Decomposition of 2-phenyl-cyclooctanone P-toluene-sulfonylhydrazone; and 3-phenylycyclooctanone P-toluenesulfonylhy-drazone; Part II: Oxadiaziridines: Synthesis and Reactivity) | ||||
Klaus Biemann | post-doc | MIT | ||
Dietrich Hoffmann | research scientist | American Health Foundation |
Children
Sign in to add traineeHansen L. Wong | grad student | 2005 | UMN |
Yanbin Lao | grad student | 2006 | UMN |
Siyi Zhang | grad student | 2009 | UMN |
Yan Zhong | grad student | 2011 | UMN |
Shana J. Sturla | post-doc | 2002-2004 | UMN |
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Publications
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Tang MK, Ostlund T, Dameh NF, et al. (2025) Reactions of [13C]-Labelled Tobacco Smoke with DNA to Generate Selected Adducts Formed Without Metabolic Activation. Carcinogenesis |
Li Y, Tang MK, Carmella SG, et al. (2024) Hydroponic Growth of [C]-Labeled Tobacco for DNA Damage Studies in Cigarette Smokers. Journal of Agricultural and Food Chemistry |
Peterson LA, Stanfill SB, Hecht SS. (2024) An Update on the Formation in Tobacco, Toxicity, and Carcinogenicity of N'-Nitrosonornicotine and 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone. Carcinogenesis |
Stanfill SB, Hecht SS, Joerger AC, et al. (2023) From cultivation to cancer: formation of -nitrosamines and other carcinogens in smokeless tobacco and their mutagenic implications. Critical Reviews in Toxicology. 1-44 |
Cheng G, Guo J, Wang R, et al. (2023) Quantitation by Liquid Chromatography-Nanoelectrospray Ionization-High-Resolution Tandem Mass Spectrometry of Multiple DNA Adducts Related to Cigarette Smoking in Oral Cells in the Shanghai Cohort Study. Chemical Research in Toxicology |
Hecht SS, Gupta PC, Sturla SJ, et al. (2022) 50 Years of Research on Tobacco-Specific Nitrosamines: A Virtual Collection of Emerging Knowledge of Chemical Toxicology of Tobacco and Nicotine Delivery Systems and Call for Contributions to a Landmark Special Issue. Chemical Research in Toxicology |
Li Y, Hecht SS. (2022) Metabolism and DNA Adduct Formation of Tobacco-Specific -Nitrosamines. International Journal of Molecular Sciences. 23 |
Hecht SS, Hatsukami DK. (2022) Smokeless tobacco and cigarette smoking: chemical mechanisms and cancer prevention. Nature Reviews. Cancer |
Li Y, Hecht SS. (2021) Identification of an -Nitrosonornicotine-Specific Deoxyadenosine Adduct in Rat Liver and Lung DNA. Chemical Research in Toxicology |
Peterson LA, Oram MK, Flavin M, et al. (2021) Coexposure to Inhaled Aldehydes or Carbon Dioxide Enhances the Carcinogenic Properties of the Tobacco-Specific Nitrosamine 4-Methylnitrosamino-1-(3-pyridyl)-1-butanone in the A/J Mouse Lung. Chemical Research in Toxicology |