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R. Luke Wiseman

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2005 Scripps Research Institute, La Jolla, La Jolla, CA, United States 
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"R. Wiseman"
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Jeffery W. Kelly grad student 2005 Scripps Institute
 (The biological and chemical implications of ligand binding to the amyloidogenic protein transthyretin.)

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Madrazo N, Khattar Z, Powers ET, et al. (2024) Mapping Stress-Responsive Signaling Pathways Induced by Mitochondrial Proteostasis Perturbations. Biorxiv : the Preprint Server For Biology
Touvier T, Veneri FA, Claessens A, et al. (2024) Activation of XBP1s attenuates disease severity in models of proteotoxic Charcot-Marie-Tooth type 1B. Biorxiv : the Preprint Server For Biology
Kline GM, Paxman RJ, Lin CY, et al. (2023) Divergent Proteome Reactivity Influences Arm-Selective Activation of the Unfolded Protein Response by Pharmacological Endoplasmic Reticulum Proteostasis Regulators. Acs Chemical Biology
Perea V, Cole C, Lebeau J, et al. (2023) PERK signaling promotes mitochondrial elongation by remodeling membrane phosphatidic acid. The Embo Journal. e113908
Kline GM, Paxman RJ, Lin CY, et al. (2023) Divergent Proteome Reactivity Influences Arm-Selective Activation of Pharmacological Endoplasmic Reticulum Proteostasis Regulators. Biorxiv : the Preprint Server For Biology
Sun S, Wang C, Zhao P, et al. (2022) Capturing the conversion of the pathogenic alpha-1-antitrypsin fold by ATF6 enhanced proteostasis. Cell Chemical Biology
Mesgarzadeh JS, Romine IC, Smith-Cohen EM, et al. (2022) ATF6 Activation Reduces Amyloidogenic Transthyretin Secretion through Increased Interactions with Endoplasmic Reticulum Proteostasis Factors. Cells. 11
Wang M, Cotter E, Wang YJ, et al. (2022) Pharmacological activation of ATF6 remodels the proteostasis network to rescue pathogenic GABA receptors. Cell & Bioscience. 12: 48
Wiseman RL, Mesgarzadeh JS, Hendershot LM. (2022) Reshaping endoplasmic reticulum quality control through the unfolded protein response. Molecular Cell. 82: 1477-1491
Mesgarzadeh JS, Buxbaum JN, Wiseman RL. (2022) Stress-responsive regulation of extracellular proteostasis. The Journal of Cell Biology. 221
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