Richard D. Hutton
Affiliations: | 2010-2015 | Chemistry | University of Canterbury, New Zealand, Christchurch, Canterbury, New Zealand |
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Parents
Sign in to add mentor| Emily J. Parker | post-doc | 2010-2015 | University of Canterbury, New Zealand |
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Publications
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| Hutton RD, Wilkinson J, Faccin M, et al. (2015) Mapping the Topography of a Protein Energy Landscape. Journal of the American Chemical Society |
| Blackmore NJ, Nazmi AR, Hutton RD, et al. (2015) Complex Formation between Two Biosynthetic Enzymes Modifies the Allosteric Regulatory Properties of Both: AN EXAMPLE OF MOLECULAR SYMBIOSIS. The Journal of Biological Chemistry. 290: 18187-98 |
| Craggs TD, Hutton RD, Brenlla A, et al. (2014) Single-molecule characterization of Fen1 and Fen1/PCNA complexes acting on flap substrates. Nucleic Acids Research. 42: 1857-72 |
| Blackmore NJ, Reichau S, Jiao W, et al. (2013) Three sites and you are out: ternary synergistic allostery controls aromatic amino acid biosynthesis in Mycobacterium tuberculosis. Journal of Molecular Biology. 425: 1582-92 |
| Jiao W, Hutton RD, Cross PJ, et al. (2012) Dynamic cross-talk among remote binding sites: the molecular basis for unusual synergistic allostery. Journal of Molecular Biology. 415: 716-26 |
| Allison TM, Hutton RD, Jiao W, et al. (2011) An extended β7α7 substrate-binding loop is essential for efficient catalysis by 3-deoxy-D-manno-octulosonate 8-phosphate synthase. Biochemistry. 50: 9318-27 |
| Reichau S, Jiao W, Walker SR, et al. (2011) Potent inhibitors of a shikimate pathway enzyme from Mycobacterium tuberculosis: combining mechanism- and modeling-based design. The Journal of Biological Chemistry. 286: 16197-207 |
| Allison TM, Hutton RD, Cochrane FC, et al. (2011) Targeting the role of a key conserved motif for substrate selection and catalysis by 3-deoxy-D-manno-octulosonate 8-phosphate synthase. Biochemistry. 50: 3686-95 |
| Webby CJ, Jiao W, Hutton RD, et al. (2010) Synergistic allostery, a sophisticated regulatory network for the control of aromatic amino acid biosynthesis in Mycobacterium tuberculosis. The Journal of Biological Chemistry. 285: 30567-76 |
| Allison TM, Yeoman JA, Hutton RD, et al. (2010) Specificity and mutational analysis of the metal-dependent 3-deoxy-D-manno-octulosonate 8-phosphate synthase from Acidithiobacillus ferrooxidans. Biochimica Et Biophysica Acta. 1804: 1526-36 |