Thomas Edward Wales
Affiliations: | 2006- | Chemistry and Chemical Biology | Northeastern University, Boston, MA, United States |
Area:
Bioanalytical ChemistryGoogle:
"Thomas Wales"Mean distance: 9.13 | S | N | B | C | P |
Parents
Sign in to add mentorMichael C. Fitzgerald | grad student | 1998-2003 | Duke | |
(Total chemical synthesis and biophysical characterization of backbone-modified protein analogues.) | ||||
John R. Engen | research scientist | 2004- | Northeastern University |
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Publications
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McHenry MW, Shi P, Camara CM, et al. (2024) Covalent inhibition of pro-apoptotic BAX. Nature Chemical Biology |
Lin DY, Kueffer LE, Juneja P, et al. (2024) Conformational heterogeneity of the BTK PHTH domain drives multiple regulatory states. Elife. 12 |
Joseph RE, Wales TE, Jayne S, et al. (2023) Impact of the clinically approved BTK inhibitors on the conformation of full-length BTK and analysis of the development of BTK resistance mutations in chronic lymphocytic leukemia. Biorxiv : the Preprint Server For Biology |
Lin DY, Kueffer LE, Juneja P, et al. (2023) Conformational heterogeneity of the BTK PHTH domain drives multiple regulatory states. Biorxiv : the Preprint Server For Biology |
A M, Wales TE, Zhou H, et al. (2023) Irisin acts through its integrin receptor in a two-step process involving extracellular Hsp90α. Molecular Cell. 83: 1903-1920.e12 |
Peterle D, DePice D, Wales TE, et al. (2022) Increase the flow rate and improve hydrogen deuterium exchange mass spectrometry. Journal of Chromatography. A. 1689: 463742 |
Du S, Alvarado JJ, Wales TE, et al. (2022) ATP-site inhibitors induce unique conformations of the acute myeloid leukemia-associated Src-family kinase, Fgr. Structure (London, England : 1993) |
Peterle D, Wales TE, Engen JR. (2022) Simple and Fast Maximally Deuterated Control (maxD) Preparation for Hydrogen-Deuterium Exchange Mass Spectrometry Experiments. Analytical Chemistry |
Prew MS, Camara CM, Botzanowski T, et al. (2022) Structural basis for defective membrane targeting of mutant enzyme in human VLCAD deficiency. Nature Communications. 13: 3669 |
Joseph RE, Lowe J, Fulton DB, et al. (2021) The Conformational State of the BTK Substrate PLCγ Contributes to Ibrutinib Resistance. Journal of Molecular Biology. 434: 167422 |