Arie Zask
Affiliations: | 1982 | Princeton University, Princeton, NJ |
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Parents
Sign in to add mentor| Martin F. Semmelhack | grad student | 1982 | Princeton |
| Koji Nakanishi | post-doc | 1986-1988 | Columbia |
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Publications
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| Ellestad G, Zask A, Berova N. (2020) The enduring legacy of Koji Nakanishi's research on bioorganic chemistry and natural products. Part 1: Isolation, structure determination and mode of action. Chirality |
| Bos PH, Lowry ER, Costa J, et al. (2019) Development of MAP4 Kinase Inhibitors as Motor Neuron-Protecting Agents. Cell Chemical Biology |
| Dieck C, Reglero-Gomez C, Zask A, et al. (2019) Abstract C005: NT5C2 small molecule inhibitor for the reversal of 6-MP resistance in acute lymphoblastic leukemia Molecular Cancer Therapeutics. 18 |
| Zask A, Ellestad G. (2017) Biomimetic syntheses of racemic natural products. Chirality |
| Qian J, Chen Y, Meng T, et al. (2016) Molecular regulation of apoptotic machinery and lipid metabolism by mTORC1/mTORC2 dual inhibitors in preclinical models of HER2+/PIK3CAmut breast cancer. Oncotarget |
| Zask A, Ellestad GA. (2015) Recent Advances in Stereoselective Drug Targeting. Chirality |
| Joshi D, Field J, Murphy J, et al. (2013) Synthesis of antioxidants for prevention of age-related macular degeneration. Journal of Natural Products. 76: 450-4 |
| Zask A, Verheijen JC, Richard DJ. (2011) Recent advances in the discovery of small-molecule ATP competitive mTOR inhibitors: a patent review. Expert Opinion On Therapeutic Patents. 21: 1109-27 |
| Zask A, Verheijen JC, Richard DJ, et al. (2010) Discovery of 2-ureidophenyltriazines bearing bridged morpholines as potent and selective ATP-competitive mTOR inhibitors. Bioorganic & Medicinal Chemistry Letters. 20: 2644-7 |
| Richard DJ, Verheijen JC, Yu K, et al. (2010) Triazines incorporating (R)-3-methylmorpholine are potent inhibitors of the mammalian target of rapamycin (mTOR) with selectivity over PI3Kalpha. Bioorganic & Medicinal Chemistry Letters. 20: 2654-7 |