Benjamin Spiller, Ph.D.
Affiliations: | 1995-1999 | University of California, Berkeley, Berkeley, CA, United States | |
| 1999- | Vanderbilt University, Nashville, TN |
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"Benjamin Spiller"Mean distance: 8.17 | S | N | B | C | P |
Children
Sign in to add trainee| Sergio Coffa | grad student | 2011 | Vanderbilt |
| Katherine L. Germane | grad student | 2011 | Vanderbilt |
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Publications
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| Kordus SL, Kroh HK, Rodríguez RC, et al. (2023) Nanobodies against C. difficile TcdA and TcdB reveal unexpected neutralizing epitopes and provide a toolkit for toxin quantitation in vivo. Plos Pathogens. 19: e1011496 |
| Farrow MA, Chumbler NM, Bloch SC, et al. (2020) A small molecule inhibitor screen reveals calcium channel signaling as a mechanistic mediator of Clostridium difficile TcdB-induced necrosis. Acs Chemical Biology |
| Kroh HK, Chandrasekaran R, Zhang Z, et al. (2017) A neutralizing antibody that blocks delivery of the enzymatic cargo of Clostridium difficile toxin TcdB into host cells. The Journal of Biological Chemistry |
| Kroh HK, Chandrasekaran R, Rosenthal K, et al. (2017) Use of a neutralizing antibody helps identify structural features critical for binding of Clostridium difficile toxin TcdA to the host cell surface. The Journal of Biological Chemistry |
| Chumbler NM, Rutherford SA, Zhang Z, et al. (2016) Crystal structure of Clostridium difficile toxin A. Nature Microbiology. 1: 15002 |
| Chumbler NM, Rutherford SA, Zhang Z, et al. (2016) Crystal structure of Clostridium difficile toxin A. Nature Microbiology. 1 |
| González-Rivera C, Campbell AM, Rutherford SA, et al. (2016) A non-oligomerizing mutant form of Helicobacter pylori VacA allows structural analysis of the p33 domain. Infection and Immunity |
| Archuleta TL, Spiller BW. (2014) A gatekeeper chaperone complex directs translocator secretion during type three secretion. Plos Pathogens. 10: e1004498 |
| McHaourab HS, Lin YL, Spiller BW. (2012) Crystal structure of an activated variant of small heat shock protein Hsp16.5. Biochemistry. 51: 5105-12 |
| Pruitt RN, Chumbler NM, Rutherford SA, et al. (2012) Structural determinants of Clostridium difficile toxin A glucosyltransferase activity. The Journal of Biological Chemistry. 287: 8013-20 |