Jason R. Porter

Affiliations: 
2009 Chemistry University of Arizona, Tucson, AZ 
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Indraneel Ghosh grad student 2009 University of Arizona
 (Split-protein reassembly methods for the detection and interrogation of biomolecular interactions and modulators thereof.)
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Publications

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Badran AH, Furman JL, Ma AS, et al. (2011) Evaluating the global CpG methylation status of native DNA utilizing a bipartite split-luciferase sensor. Analytical Chemistry. 83: 7151-7
Porter JR, Helmers MR, Wang P, et al. (2010) Profiling small molecule inhibitors against helix-receptor interactions: the Bcl-2 family inhibitor BH3I-1 potently inhibits p53/hDM2. Chemical Communications (Cambridge, England). 46: 8020-2
Henchey LK, Porter JR, Ghosh I, et al. (2010) High specificity in protein recognition by hydrogen-bond-surrogate α-helices: selective inhibition of the p53/MDM2 complex. Chembiochem : a European Journal of Chemical Biology. 11: 2104-7
Furman JL, Badran AH, Ajulo O, et al. (2010) Toward a general approach for RNA-templated hierarchical assembly of split-proteins. Journal of the American Chemical Society. 132: 11692-701
Stains CI, Furman JL, Porter JR, et al. (2010) A general approach for receptor and antibody-targeted detection of native proteins utilizing split-luciferase reassembly. Acs Chemical Biology. 5: 943-52
Porter JR, Lockwood SH, Segal DJ, et al. (2010) Seeing genetic and epigenetic information without DNA denaturation using sequence-enabled reassembly (SEER). Methods in Molecular Biology (Clifton, N.J.). 649: 365-82
Jester BW, Cox KJ, Gaj A, et al. (2010) A coiled-coil enabled split-luciferase three-hybrid system: applied toward profiling inhibitors of protein kinases. Journal of the American Chemical Society. 132: 11727-35
Shekhawat SS, Porter JR, Sriprasad A, et al. (2009) An autoinhibited coiled-coil design strategy for split-protein protease sensors. Journal of the American Chemical Society. 131: 15284-90
Porter JR, Stains CI, Jester BW, et al. (2008) A general and rapid cell-free approach for the interrogation of protein-protein, protein-DNA, and protein-RNA interactions and their antagonists utilizing split-protein reporters. Journal of the American Chemical Society. 130: 6488-97
Porter JR, Stains CI, Segal DJ, et al. (2007) Split beta-lactamase sensor for the sequence-specific detection of DNA methylation. Analytical Chemistry. 79: 6702-8
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