Young-Ok You, Ph.D.
Affiliations: | 2008- | Brown University, Providence, RI |
Website:
http://casey.brown.edu/chemistry/research/dec/resgrp/Google:
"Young-Ok You"Mean distance: 7.99 | S | N | B | C | P |
Parents
Sign in to add mentor| Wilfred A. van der Donk | grad student | 2008 | UIUC | |
| (Mechanistic investigations of dehydration of lacticin 481 synthetase and exploring its biochemical applications.) | ||||
| David E. Cane | post-doc | 2008- | Brown | |
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Publications
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| Al-Dhelaan R, Russo PS, Padden SE, et al. (2019) Condensation-incompetent Ketosynthase inhibits trans-Acyltransferase activity. Acs Chemical Biology |
| You YO, Shah DD, Cane DE. (2017) Stereospecific Formation of E- and Z- Disubstituted Double Bonds by Dehydratase Domains from Modules 1 and 2 of the Fostriecin Polyketide Synthase. Journal of the American Chemical Society |
| You Y, Zhou M, Lu H, et al. (2015) Sanshool from Zanthoxylum L. induces apoptosis in human hepatocarcinoma HepG2 cells Food Science and Biotechnology. 24: 2169-2175 |
| Gay D, You YO, Keatinge-Clay A, et al. (2013) Structure and stereospecificity of the dehydratase domain from the terminal module of the rifamycin polyketide synthase. Biochemistry. 52: 8916-28 |
| You YO, Khosla C, Cane DE. (2013) Stereochemistry of reductions catalyzed by methyl-epimerizing ketoreductase domains of polyketide synthases. Journal of the American Chemical Society. 135: 7406-9 |
| Valenzano CR, You YO, Garg A, et al. (2010) Stereospecificity of the dehydratase domain of the erythromycin polyketide synthase. Journal of the American Chemical Society. 132: 14697-9 |
| Lee MV, Ihnken LA, You YO, et al. (2009) Distributive and directional behavior of lantibiotic synthetases revealed by high-resolution tandem mass spectrometry. Journal of the American Chemical Society. 131: 12258-64 |
| You YO, Levengood MR, Ihnken LA, et al. (2009) Lacticin 481 synthetase as a general serine/threonine kinase. Acs Chemical Biology. 4: 379-85 |
| You YO, van der Donk WA. (2007) Mechanistic investigations of the dehydration reaction of lacticin 481 synthetase using site-directed mutagenesis. Biochemistry. 46: 5991-6000 |