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Nathaniel I. Martin, Ph.D.

Affiliations:	2004		University of Alberta, Edmonton, Alberta, Canada
	2007-2018	Chemistry	Utrecht University, Utrecht, Netherlands
	2018-	Biological Chemisyr	Leiden University, Leiden, Netherlands

Area:

Chemical biology

Website:

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"Nathaniel Martin"

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Parents

John C. Vederas	grad student	2004	University of Alberta
Michael A. Marletta	post-doc	2004-2007	UC Berkeley

Children

Peter 't Hart	grad student		Universiteit Utrecht
Karol Al Ayed	grad student		Leiden
Timo Koopmans	grad student	2016	Utrecht

Collaborators

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Publications

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Buijs NP, Matheson EJ, Cochrane SA, et al. (2023) Targeting membrane-bound bacterial cell wall precursors: a tried and true antibiotic strategy in nature and the clinic. Chemical Communications (Cambridge, England)
Ballantine RD, Al Ayed K, Bann SJ, et al. (2023) Linearization of the Brevicidine and Laterocidine Lipopeptides Yields Analogues That Retain Full Antibacterial Activity. Journal of Medicinal Chemistry
Deisinger JP, Arts M, Kotsogianni I, et al. (2023) Dual targeting of the class V lanthipeptide antibiotic cacaoidin. Iscience. 26: 106394
Al Ayed K, Zamarbide Losada D, Machushynets NV, et al. (2023) Total Synthesis and Structure Assignment of the Relacidine Lipopeptide Antibiotics and Preparation of Analogues with Enhanced Stability. Acs Infectious Diseases
Ballantine RD, Al Ayed K, Bann SJ, et al. (2022) Synthesis and structure-activity relationship studies of N-terminal analogues of the lipopeptide antibiotics brevicidine and laterocidine. Rsc Medicinal Chemistry. 13: 1640-1643
Buijs N, Vlaming H, van Haren M, et al. (2022) Synthetic Studies with Bacitracin A and Preparation of Analogues Containing Alternative Zinc Binding Groups. Chembiochem : a European Journal of Chemical Biology
Al Ayed K, Ballantine RD, Hoekstra M, et al. (2022) Synthetic studies with the brevicidine and laterocidine lipopeptide antibiotics including analogues with enhanced properties and efficacy. Chemical Science. 13: 3563-3570
Kotsogianni I, Wood TM, Alexander FM, et al. (2021) Binding Studies Reveal Phospholipid Specificity and Its Role in the Calcium-Dependent Mechanism of Action of Daptomycin. Acs Infectious Diseases
Tehrani KHME, Brüchle NC, Wade N, et al. (2020) Small Molecule Carboxylates Inhibit Metallo-β-lactamases and Resensitize Carbapenem-Resistant Bacteria to Meropenem. Acs Infectious Diseases
Tehrani KHME, Fu H, Brüchle NC, et al. (2020) Aminocarboxylic acids related to aspergillomarasmine A (AMA) and ethylenediamine-N,N'-disuccinic acid (EDDS) are strong zinc-binders and inhibitors of the metallo-beta-lactamase NDM-1. Chemical Communications (Cambridge, England)

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