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David C. Bom, Ph.D. - Publications

Affiliations: 
2000 University of Pittsburgh, Pittsburgh, PA, United States 
Area:
radical chemistry
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7 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2002 Liu X, Lynn BC, Zhang J, Song L, Bom D, Du W, Curran DP, Burke TG. A versatile prodrug approach for liposomal core-loading of water-insoluble camptothecin anticancer drugs. Journal of the American Chemical Society. 124: 7650-1. PMID 12083906 DOI: 10.1021/Ja0256212  0.523
2000 Du W, Gabarda AE, Bom D, Curran DP. The combinatorial synthesis of racemic homosilatecan libraries via a cascade radical annulation. Annals of the New York Academy of Sciences. 922: 317-9. PMID 11193911 DOI: 10.1111/J.1749-6632.2000.Tb07053.X  0.554
2000 Curran DP, Josien H, Bom D, Gabarda AE, Du W. The cascade radical annulation approach to new analogues of camptothecins. Combinatorial synthesis of silatecans and homosilatecans. Annals of the New York Academy of Sciences. 922: 112-21. PMID 11193887 DOI: 10.1111/J.1749-6632.2000.Tb07030.X  0.592
2000 Bom D, Curran DP, Kruszewski S, Zimmer SG, Thompson Strode J, Kohlhagen G, Du W, Chavan AJ, Fraley KA, Bingcang AL, Latus LJ, Pommier Y, Burke TG. The novel silatecan 7-tert-butyldimethylsilyl-10-hydroxycamptothecin displays high lipophilicity, improved human blood stability, and potent anticancer activity. Journal of Medicinal Chemistry. 43: 3970-80. PMID 11052802 DOI: 10.1021/Jm000144O  0.555
1999 Bom D, Curran DP, Chavan AJ, Kruszewski S, Zimmer SG, Fraley KA, Burke TG. Novel A,B,E-ring-modified camptothecins displaying high lipophilicity and markedly improved human blood stabilities. Journal of Medicinal Chemistry. 42: 3018-22. PMID 10447944 DOI: 10.1021/Jm9902279  0.477
1998 Josien H, Ko S, Bom D, Curran DP. A General Synthetic Approach to the (20S)-Camptothecin Family of Antitumor Agents by a Regiocontrolled Cascade Radical Cyclization of Aryl Isonitriles Chemistry - a European Journal. 4: 67-83. DOI: 10.1002/(Sici)1521-3765(199801)4:1<67::Aid-Chem67>3.0.Co;2-F  0.519
1997 Josien H, Bom D, Curran DP, Zheng Y, Chou T. 7-Silylcamptothecins (silatecans): A new family of camptothecin antitumor agents Bioorganic & Medicinal Chemistry Letters. 7: 3189-3194. DOI: 10.1016/S0960-894X(97)10181-0  0.494
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