Karam El-Bayoumy - Publications

Affiliations: 
Pennsylvania State University, State College, PA, United States 
Area:
Biochemistry, Molecular Biology, Histology Biology, Oncology
Website:
https://profiles.psu.edu/profiles/display/113456

175 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Chen KM, Sun YW, Kawasawa YI, Salzberg AC, Zhu J, Gowda K, Aliaga C, Amin S, Atkins H, El-Bayoumy K. Black Raspberry Inhibits Oral Tumors in Mice Treated with the Tobacco Smoke Constituent Dibenzo(def,p)chrysene via Genetic and Epigenetic Alterations. Cancer Prevention Research (Philadelphia, Pa.). PMID 31969344 DOI: 10.1158/1940-6207.Capr-19-0496  0.387
2019 Guttenplan JB, Chen KM, Sun YW, Shalaby NAE, Kosinska W, Desai D, Gowda K, Amin S, El-Bayoumy K. The effects of the tobacco carcinogens N`-nitrosonornicotine and dibenzo[a,l]pyrene individually and in combination on DNA damage in human oral leukoplakia and on mutagenicity, and mutation profiles in lacI mouse tongue. Chemical Research in Toxicology. PMID 31433626 DOI: 10.1021/Acs.Chemrestox.9B00257  0.387
2019 El-Bayoumy K, Manni A. Customized Prevention Trials Could Resolve the Controversy of the Effects of Omega-3 Fatty Acids on Cancer. Nutrition and Cancer. 1-4. PMID 31407927 DOI: 10.1080/01635581.2019.1651348  0.341
2018 Chen KM, Sun YW, Cooper TK, Benitez G, Aliaga C, Zhu J, Gowda K, Amin S, El-Bayoumy K. Comparative tumorigenicity and DNA damage induced by dibenzo[def,p]chrysene and its metabolites in the mouse ovary. Chemical Research in Toxicology. PMID 30260214 DOI: 10.1021/Acs.Chemrestox.8B00152  0.413
2017 Manni A, El-Bayoumy K, Thompson H. Docosahexaenoic Acid in Combination with Dietary Energy Restriction for Reducing the Risk of Obesity Related Breast Cancer. International Journal of Molecular Sciences. 19. PMID 29271901 DOI: 10.3390/Ijms19010028  0.307
2017 Chen KM, Guttenplan JB, Sun YW, Cooper T, Shalaby NA, Kosinska W, Benitez G, Aliaga C, Zhu J, Liao J, Gowda K, Amin S, Stoner G, El-Bayoumy K. Effects of Black Raspberry on Dibenzo[a,l]Pyrene Diol Epoxide Induced DNA Adducts, Mutagenesis and Tumorigenesis in the Mouse Oral Cavity. Cancer Prevention Research (Philadelphia, Pa.). PMID 29158340 DOI: 10.1158/1940-6207.Capr-17-0278  0.402
2017 Chen KM, Schell TD, Richie JP, Sun YW, Zhang SM, Calcagnotto A, Aliga C, Gowda K, Amin S, El-Bayoumy K. Effects of chronic alcohol consumption on DNA damage and immune regulation induced by the environmental pollutant dibenzo[a,l]pyrene in oral tissues of mice. Journal of Environmental Science and Health. Part C, Environmental Carcinogenesis & Ecotoxicology Reviews. 0. PMID 29106334 DOI: 10.1080/10590501.2017.1391514  0.324
2017 Sun YW, Chen KM, Imamura Kawasawa Y, Salzberg AC, Cooper TK, Caruso C, Aliaga C, Zhu J, Gowda K, Amin S, El-Bayoumy K. Hypomethylated Fgf3 is a potential biomarker for early detection of oral cancer in mice treated with the tobacco carcinogen dibenzo[def,p]chrysene. Plos One. 12: e0186873. PMID 29073177 DOI: 10.1371/Journal.Pone.0186873  0.371
2017 Guttenplan J, Chen KM, Sun YW, Lajara B, Shalaby NA, Kosinska W, Benitez G, Gowda K, Amin S, Stoner GD, El-Bayoumy K. Effects of Black Raspberry Extract and Berry Compounds on Repair of DNA Damage, and Mutagenesis Induced by Chemical and Physical Agents in Human Oral Leukoplakia and Rat Oral Fibroblasts. Chemical Research in Toxicology. PMID 29068672 DOI: 10.1021/Acs.Chemrestox.7B00242  0.359
2017 El-Bayoumy K, Chen KM, Zhang SM, Sun YW, Amin S, Stoner G, Guttenplan JB. Carcinogenesis of the Oral Cavity: Environmental Causes and Potential Prevention by Black Raspberry. Chemical Research in Toxicology. 30: 126-144. PMID 28092946 DOI: 10.1021/Acs.Chemrestox.6B00306  0.408
2017 Guttenplan JB, Chen K, Sun Y, Teicher R, Kosinska W, Gowda K, Amin S, Stoner GD, El-Bayoumy K. Abstract 503: Enhanced repair of bulky DNA adducts induced by a tobacco carcinogen and UV light in human oral epithelial cells by black raspberry extract Cancer Research. 77: 503-503. DOI: 10.1158/1538-7445.Am2017-503  0.302
2017 Manni A, Richie JP, Schetter SE, Calcagnotto A, Trushin N, Aliaga C, El-Bayoumy K. Abstract 236: Stearoyl-CoA desaturase-1, a novel target of omega-3 fatty acids for reducing breast cancer risk in obese postmenopausal women Cancer Research. 77: 236-236. DOI: 10.1158/1538-7445.Am2017-236  0.35
2016 Guttenplan J, Chen KM, Sun YW, Kosinska W, Zhou Y, Kim SA, Sung Y, Gowda K, Amin S, Stoner G, El-Bayoumy K. Effects of black raspberry extract and protocatechuic acid on carcinogen-DNA adducts and mutagenesis, and oxidative stress in rat and human oral cells. Cancer Prevention Research (Philadelphia, Pa.). PMID 27267891 DOI: 10.1158/1940-6207.Capr-16-0003  0.359
2016 Skibinski CG, Das A, Chen KM, Liao J, Manni A, Kester M, El-Bayoumy K. A novel biologically active acid stable liposomal formulation of docosahexaenoic acid in human breast cancer cell lines. Chemico-Biological Interactions. PMID 27041074 DOI: 10.1016/J.Cbi.2016.03.035  0.365
2016 Sun Y, El-Bayoumy K, Kawasawa YI, Salzberg A, Aliaga C, Gowdahalli K, Amin S, Chen K. Abstract 4454: Genome-wide analysis of DNA methylation induced by environmental carcinogen dibenzo[def,p]chrysene in ovarian tissues of mice Cancer Research. 76: 4454-4454. DOI: 10.1158/1538-7445.Am2016-4454  0.375
2016 Guttenplan JB, Sun Y, Chen K, Kosinska W, El-Bayoumy K. Abstract 4063: Effects of electronic cigarettes (E-cigs) and hookah on the metabolic activation of the tobacco carcinogen, benzo(a)pyrene (BaP), and cellular proliferation in human oral leukoplakia cells Cancer Research. 76: 4063-4063. DOI: 10.1158/1538-7445.Am2016-4063  0.315
2015 Sandhu N, Schetter SE, Liao J, Hartman TJ, Richie JP, McGinley JN, Thompson HJ, Prokopczyk B, Dubrock C, Signori C, Hamilton C, Calcagnotto A, Trushin N, Aliaga C, Demers L, ... El-Bayoumy K, et al. Influence of obesity on breast density reduction by omega-3 fatty acids: Evidence from a randomized clinical trial. Cancer Prevention Research (Philadelphia, Pa.). PMID 26714774 DOI: 10.1158/1940-6207.Capr-15-0235  0.325
2015 Manni A, El-Bayoumy K, Skibinski CG, Thompson HJ, Santucci-Pereira J, Bidinotto LT, Russo J. Combination of Antiestrogens and Omega-3 Fatty Acids for Breast Cancer Prevention. Biomed Research International. 2015: 638645. PMID 26339626 DOI: 10.1155/2015/638645  0.331
2015 Turbitt WJ, Black AJ, Collins SD, Meng H, Xu H, Washington S, Aliaga C, El-Bayoumy K, Manni A, Rogers CJ. Fish Oil Enhances T Cell Function and Tumor Infiltration and Is Correlated With a Cancer Prevention Effect in HER-2/neu But Not PyMT Transgenic Mice. Nutrition and Cancer. 67: 965-75. PMID 26226376 DOI: 10.1080/01635581.2015.1060351  0.34
2015 Rice SJ, Liu X, Miller B, Joshi M, Zhu J, Caruso C, Gilbert C, Toth J, Reed M, Rassaei N, Das A, Barochia A, El-Bayoumy K, Belani CP. Proteomic profiling of human plasma identifies apolipoprotein E as being associated with smoking and a marker for squamous metaplasia of the lung. Proteomics. PMID 26058877 DOI: 10.1002/Pmic.201500029  0.304
2015 Sun YW, El-Bayoumy K, Aliaga C, Awad AS, Gowda K, Amin S, Chen KM. Tissue Distribution, Excretion and Pharmacokinetics of the Environmental Pollutant Dibenzo[def,p]chrysene in Mice. Chemical Research in Toxicology. PMID 26034881 DOI: 10.1021/Acs.Chemrestox.5B00097  0.357
2015 Pogash TJ, El-Bayoumy K, Amin S, Gowda K, de Cicco RL, Barton M, Su Y, Russo IH, Himmelberger JA, Slifker M, Manni A, Russo J. Oxidized derivative of docosahexaenoic acid preferentially inhibit cell proliferation in triple negative over luminal breast cancer cells. In Vitro Cellular & Developmental Biology. Animal. 51: 121-7. PMID 25413005 DOI: 10.1007/S11626-014-9822-6  0.339
2015 Guttenplan JB, Kim S, Zhou Y, Kosinska W, Golgotiu A, Amin S, Stoner GD, Sun Y, Chen K, El-Bayoumy K. Abstract 915: Effects of black raspberry extract (BRB) and related compounds on mutagenesis induced by metabolites of the tobacco carcinogen, dibenzo(a,l)pyrene in cultured rat oral fibroblasts; and on oxidative stress in human oral cancer cells Cancer Research. 75: 915-915. DOI: 10.1158/1538-7445.Am2015-915  0.385
2015 Chen K, Sun Y, Aliaga C, Awad A, Gowda K, Amin S, El-Bayoumy K. Abstract 4530: Tissue distribution, excretion and pharmacokinetics of the environmental pollutant and the tobacco smoke constituent dibenzo[a,l]pyrene in mice Cancer Research. 75: 4530-4530. DOI: 10.1158/1538-7445.Am2015-4530  0.384
2015 Sun Y, Chen K, Kawasawa YI, Salzberg A, Aliaga C, Gowdahalli K, Amin S, Stoner G, El-Bayoumy K. Abstract 2955: The effects of the environmental carcinogen dibenzo[a,l]pyrene on genome-wide methylation and the impact of dietary black raspberry in mouse oral tissues Cancer Research. 75: 2955-2955. DOI: 10.1158/1538-7445.Am2015-2955  0.373
2015 Skibinski CG, Das A, Chen K, Trushin N, Prokopczyk B, Aliaga C, Kester M, Manni A, El-Bayoumy K. Abstract 2803: Oral administration of an acid stable liposomal formulation of docosahexaenoic acid (DHA) delivers DHA and its LOX-metabolites to the circulation and the breast tissue of sprague dawley rats Cancer Research. 75: 2803-2803. DOI: 10.1158/1538-7445.Am2015-2803  0.376
2015 Sandhu N, Schetter SE, Liao J, Hartman TJ, Richie JP, El-Bayoumy K, Prokopczyk B, DuBrock C, Signori C, Hamilton C, Demers LM, Manni A. Abstract 1904: Randomized clinical trial testing the efficacy of the combination of omega-3-fatty acids (n-3FA) and the antiestrogen raloxifene in reducing breast density (BD) in postmenopausal women Cancer Research. 75: 1904-1904. DOI: 10.1158/1538-7445.Am2015-1904  0.332
2014 Richie JP, Das A, Calcagnotto AM, Sinha R, Neidig W, Liao J, Lengerich EJ, Berg A, Hartman TJ, Ciccarella A, Baker A, Kaag MG, Goodin S, DiPaola RS, El-Bayoumy K. Comparative effects of two different forms of selenium on oxidative stress biomarkers in healthy men: a randomized clinical trial. Cancer Prevention Research (Philadelphia, Pa.). 7: 796-804. PMID 24938534 DOI: 10.1158/1940-6207.Capr-14-0042  0.322
2014 Zhang SM, Chen KM, Sun YW, Aliaga C, Lin JM, Sharma AK, Amin S, El-Bayoumy K. Simultaneous detection of deoxyadenosine and deoxyguanosine adducts in the tongue and other oral tissues of mice treated with Dibenzo[a,l]pyrene. Chemical Research in Toxicology. 27: 1199-206. PMID 24911113 DOI: 10.1021/Tx5001078  0.351
2014 Skibinski CG, Das A, Kester M, Chen K, Manni A, El-Bayoumy K. Abstract 5421: A novel biologically active acid stable liposomal formulation of docosahexaenoic acid (DHA) for breast cancer prevention Cancer Research. 74: 5421-5421. DOI: 10.1158/1538-7445.Am2014-5421  0.378
2014 Kaag MG, Richie JP, Das A, Calcagnotto A, Sinha R, Neidig W, Liao J, Lengreich EJ, Berg A, Hartman TJ, Ciccarella A, Baker A, Boyiri T, Goodin S, DiPaola RS, ... El-Bayoumy K, et al. Abstract 3244: Supplementation with selenium-enriched yeast but not selenomethionine reduces oxidative stress in healthy men in a randomized clinical trial Cancer Research. 74: 3244-3244. DOI: 10.1158/1538-7445.Am2014-3244  0.339
2014 Guttenplan JB, Kosinska W, Han T, Chen K, Zhang S, Gowdahalli K, Shantu A, Stoner G, El-Bayoumy K. Abstract 252: Effects of black raspberry extract (BRB) and related compounds on mutagenesis induced by the tobacco carcinogen, dibenzo(a,l)pyrene and its metabolites in cultured rat oral fibroblasts Cancer Research. 74: 252-252. DOI: 10.1158/1538-7445.Am2014-252  0.415
2014 Chen K, Zhang S, Sun Y, Aliaga C, Gowdahalli K, Amin S, Stoner G, El-Bayoumy K. Abstract 230: The inhibitory effects of an anthocyanin enriched fraction of black raspberry (BRB), protocatechuic acid and ferulic acid on DB[a,l]P-induced DNA adduct formation in mouse oral tissues Cancer Research. 74: 230-230. DOI: 10.1158/1538-7445.Am2014-230  0.421
2013 Krzeminski J, Kropachev K, Reeves D, Kolbanovskiy A, Kolbanovskiy M, Chen KM, Sharma AK, Geacintov N, Amin S, El-Bayoumy K. Adenine-DNA adduct derived from the nitroreduction of 6-nitrochrysene is more resistant to nucleotide excision repair than guanine-DNA adducts. Chemical Research in Toxicology. 26: 1746-54. PMID 24112095 DOI: 10.1021/Tx400296X  0.313
2013 Skibinski CG, Thompson HJ, Das A, Manni A, Bortner JD, Stanley A, Stanley BA, El-Bayoumy K. Proteomic changes induced by effective chemopreventive ratios of n-3:n-6 fatty acids and tamoxifen against MNU-induced mammary cancer in the rat. Cancer Prevention Research (Philadelphia, Pa.). 6: 979-88. PMID 23880232 DOI: 10.1158/1940-6207.Capr-13-0152  0.353
2013 Chen KM, Guttenplan JB, Zhang SM, Aliaga C, Cooper TK, Sun YW, DelTondo J, Kosinska W, Sharma AK, Jiang K, Bruggeman R, Ahn K, Amin S, El-Bayoumy K. Mechanisms of oral carcinogenesis induced by dibenzo[a,l]pyrene: an environmental pollutant and a tobacco smoke constituent. International Journal of Cancer. Journal International Du Cancer. 133: 1300-9. PMID 23483552 DOI: 10.1002/Ijc.28152  0.368
2013 Sun YW, Guttenplan JB, Cooper T, Krzeminski J, Aliaga C, Boyiri T, Kosinska W, Zhao ZL, Chen KM, Berg A, Amin S, El-Bayoumy K. Mechanisms underlying the varied mammary carcinogenicity of the environmental pollutant 6-nitrochrysene and its metabolites (-)-[R,R]- and (+)-[S,S]-1,2-dihydroxy-1,2-dihydro-6-nitrochrysene in the rat. Chemical Research in Toxicology. 26: 547-54. PMID 23461617 DOI: 10.1021/Tx300478Z  0.302
2013 Chen K, Zhang S, Aliaga C, Sun Y, Berg A, Sharma A, Amin S, Stoner G, El-Bayoumy K. Abstract 3708: Effects of black raspberry and related components on DB[a,l]P-induced DNA adduct formation in mouse oral tissues. Cancer Research. 73: 3708-3708. DOI: 10.1158/1538-7445.Am2013-3708  0.346
2013 Turbitt WJ, Collins SD, Xu H, Washington S, Aliaga C, El-Bayoumy K, Manni A, Rogers CJ. Abstract 3691: Fish oil increases immune cell infiltration of tumors and reduces the incidence of mammary carcinogenesis in Her2neu mice. Cancer Research. 73: 3691-3691. DOI: 10.1158/1538-7445.Am2013-3691  0.349
2013 Manni A, Richie JP, Trushin N, Prokopczyk B, Patterson A, Heuvel JPV, Washington S, Xu H, Aliaga C, Das A, Gowda K, Amin S, Liao J, Thompson H, El-Bayoumy K. Abstract 3657: Identification of active metabolites of docosohexaenoic acid (DHA): A first step towards unraveling the fish oil/breast cancer conundrum. Cancer Research. 73: 3657-3657. DOI: 10.1158/1538-7445.Am2013-3657  0.436
2013 Zhang S, Chen K, Richie JR, Calcagnotto A, Aliaga C, Berg A, Sun Y, Sharma AK, Amin S, El-Bayoumy K. Abstract 3602: Effect of alcohol on DB[a,l]P, an environmental pollutant and a tobacco smoke constituent, on DNA adduct formation in mouse oral tissues. Cancer Research. 73: 3602-3602. DOI: 10.1158/1538-7445.Am2013-3602  0.377
2013 Pogash TJ, Cicco RLd, Pressly B, Russo IH, Himmelberger JA, Amin S, Gowda K, El-Bayoumy K, Manni A, Russo J. Abstract 2600: Polyunsaturated omega-3 fatty acids and their metabolites preferentially inhibit cell proliferation and motility in triple negative over luminal breast cancer cells. Cancer Research. 73: 2600-2600. DOI: 10.1158/1538-7445.Am2013-2600  0.353
2013 Thompson HJ, Jiang W, Zhu Z, Heuvel JPV, Amin S, Gowda K, Manni A, El-Bayoumy K. Abstract 2582: In vitro effects of 4-OXO-docosahexaenoic ester on cell signaling in molecular subtypes of human breast cancer cell lines. Cancer Research. 73: 2582-2582. DOI: 10.1158/1538-7445.Am2013-2582  0.362
2013 Skibinski CG, Thompson HJ, Das A, Manni A, El-Bayoumy K. Abstract 2486: Plasma proteomic changes induced by effective chemopreventive ratios of N-3:N-6 fatty acids against MNU-induced mammary carcinogenesis of the rat. Cancer Research. 73: 2486-2486. DOI: 10.1158/1538-7445.Am2013-2486  0.37
2012 Bidinotto LT, de Cicco RL, Vanegas JE, Santucci-Pereira J, Vanden Heuvel JP, Washington S, Aliaga C, Xu H, Russo IH, Manni A, El-Bayoumy K, Russo J. Fish oil alters tamoxifen-modulated expression of mRNAs that encode genes related to differentiation, proliferation, metastasis, and immune response in rat mammary tumors. Nutrition and Cancer. 64: 991-9. PMID 23061905 DOI: 10.1080/01635581.2012.712736  0.322
2012 Signori C, DuBrock C, Richie JP, Prokopczyk B, Demers LM, Hamilton C, Hartman TJ, Liao J, El-Bayoumy K, Manni A. Administration of omega-3 fatty acids and Raloxifene to women at high risk of breast cancer: interim feasibility and biomarkers analysis from a clinical trial. European Journal of Clinical Nutrition. 66: 878-84. PMID 22669332 DOI: 10.1038/Ejcn.2012.60  0.332
2012 Emmert SW, El-Bayoumy K, Das A, Sun YW, Amin S, Desai D, Aliaga C, Richie JP. Induction of lung glutathione and glutamylcysteine ligase by 1,4-phenylenebis(methylene)selenocyanate and its glutathione conjugate: role of nuclear factor-erythroid 2-related factor 2. Free Radical Biology & Medicine. 52: 2064-71. PMID 22542796 DOI: 10.1016/J.Freeradbiomed.2012.03.018  0.35
2012 Trushin N, Alam S, El-Bayoumy K, Krzeminski J, Amin SG, Gullett J, Meyers C, Prokopczyk B. Comparative metabolism of benzo[a]pyrene by human keratinocytes infected with high-risk human papillomavirus types 16 and 18 as episomal or integrated genomes. Journal of Carcinogenesis. 11: 1. PMID 22368516 DOI: 10.4103/1477-3163.92309  0.303
2012 Facompre ND, Sinha I, El-Bayoumy K, Pinto JT, Sinha R. Remarkable inhibition of mTOR signaling by the combination of rapamycin and 1,4-phenylenebis(methylene)selenocyanate in human prostate cancer cells. International Journal of Cancer. Journal International Du Cancer. 131: 2134-42. PMID 22307455 DOI: 10.1002/Ijc.27468  0.322
2012 Richie JP, Das A, Calcagnotto AM, Aliaga CA, El-Bayoumy K. Age related changes in selenium and glutathione levels in different lobes of the rat prostate. Experimental Gerontology. 47: 223-8. PMID 22212532 DOI: 10.1016/J.Exger.2011.11.015  0.301
2012 Chen KM, Zhang SM, Aliaga C, Sun YW, Cooper T, Gowdahalli K, Zhu J, Amin S, El-Bayoumy K. Induction of ovarian cancer and DNA adducts by Dibenzo[a,l]pyrene in the mouse. Chemical Research in Toxicology. 25: 374-80. PMID 22107356 DOI: 10.1021/Tx2004322  0.39
2012 Guttenplan JB, Kosinska W, Zhao ZL, Chen KM, Aliaga C, DelTondo J, Cooper T, Sun YW, Zhang SM, Jiang K, Bruggeman R, Sharma AK, Amin S, Ahn K, El-Bayoumy K. Mutagenesis and carcinogenesis induced by dibenzo[a,l]pyrene in the mouse oral cavity: a potential new model for oral cancer. International Journal of Cancer. Journal International Du Cancer. 130: 2783-90. PMID 21815141 DOI: 10.1002/Ijc.26344  0.388
2012 Wilson RT, Bortner JD, Berg A, Roff A, Das A, Richie J, Barnholtz-Sloan J, El-Bayoumy K. Abstract 670: Cigarette smoking, race, and genetic ancestry in association with plasma vitamin D-binding protein (VDBP) in healthy African Americans (AA) and Caucasian Americans (CA) Cancer Research. 72: 670-670. DOI: 10.1158/1538-7445.Am2012-670  0.303
2012 Zhang S, Sun Y, Chen K, Aliaga C, Gowdahalli K, Amin S, El-Bayoumy K. Abstract 5470: Genotoxic effect and epigenetic alterations induced by the environmental carcinogen dibenzo[a, l]pyrene in oral tissues of mice Cancer Research. 72: 5470-5470. DOI: 10.1158/1538-7445.Am2012-5470  0.406
2012 Zhang S, Chen K, Aliaga C, Gowdahalli K, Amin S, El-Bayoumy K. Abstract 5469: Detection of deoxyguanosine adducts in the oral tissues of mice treated with the environmental carcinogen dibenzo[a, l]pyrene by LC-MS/MS Cancer Research. 72: 5469-5469. DOI: 10.1158/1538-7445.Am2012-5469  0.364
2012 Sun Y, Krzeminski J, Aliaga C, Manni A, Amin S, El-Bayoumy K. Abstract 5453: The effect of ovarian hormones on the induction of mammary tumors induced by the environmental pollutant 6-nitrochrysene Cancer Research. 72: 5453-5453. DOI: 10.1158/1538-7445.Am2012-5453  0.372
2011 Signori C, El-Bayoumy K, Russo J, Thompson HJ, Richie JP, Hartman TJ, Manni A. Chemoprevention of breast cancer by fish oil in preclinical models: trials and tribulations. Cancer Research. 71: 6091-6. PMID 21933885 DOI: 10.1158/0008-5472.Can-11-0977  0.329
2011 Manni A, Richie JP, Xu H, Washington S, Aliaga C, Cooper TK, Bruggeman R, Das A, Prokopczyk B, Calcagnotto A, Trushin N, Dickinson R, Liao J, Verderame MF, El-Bayoumy K. Effects of fish oil and Tamoxifen on preneoplastic lesion development and biomarkers of oxidative stress in the early stages of N-methyl-N-nitrosourea-induced rat mammary carcinogenesis. International Journal of Oncology. 39: 1153-64. PMID 21892590 DOI: 10.3892/Ijo.2011.1133  0.385
2011 Manni A, Xu H, Washington S, Aliaga C, Das A, Cooper T, Richie JP, Prokopczyk B, Calcagnotto A, Trushin N, Van den Heuvel JP, Hamilton C, Demers LM, Liao J, Verderame MF, ... El-Bayoumy K, et al. The effects of Tamoxifen and fish oil on mammary carcinogenesis in polyoma middle T transgenic mice. Hormones & Cancer. 2: 249-59. PMID 21769696 DOI: 10.1007/S12672-011-0078-2  0.36
2011 Zhang SM, Chen KM, Aliaga C, Sun YW, Lin JM, Sharma AK, Amin S, El-Bayoumy K. Identification and quantification of DNA adducts in the oral tissues of mice treated with the environmental carcinogen dibenzo[a,l]pyrene by HPLC-MS/MS. Chemical Research in Toxicology. 24: 1297-303. PMID 21736370 DOI: 10.1021/Tx200188J  0.354
2011 Krzeminski J, Kropachev K, Kolbanovskiy M, Reeves D, Kolbanovskiy A, Yun BH, Geacintov NE, Amin S, El-Bayoumy K. Inefficient nucleotide excision repair in human cell extracts of the N-(deoxyguanosin-8-yl)-6-aminochrysene and 5-(deoxyguanosin-N(2)-yl)-6-aminochrysene adducts derived from 6-nitrochrysene. Chemical Research in Toxicology. 24: 65-72. PMID 21114286 DOI: 10.1021/Tx100284H  0.361
2011 Bidinotto LT, Vanegas JE, Heuvel JPV, Cicco RLd, Santucci-Pereira J, Washington S, Xu H, Russo IH, El-Bayoumy K, Manni A, Russo J. Abstract 5578: Transcriptomic changes in tamoxifen-treated mammary tumors in Sprague-Dawley rats fed with omega-3 or omega-6 rich diets Cancer Research. 71: 5578-5578. DOI: 10.1158/1538-7445.Am2011-5578  0.353
2011 Manni A, Richie JP, Xu H, Washington S, Aliaga C, Cooper TK, Bruggeman R, Prokopczyk B, Calcagnotto A, Trushin N, Liao J, Verderame MF, El-Bayoumy K. Abstract 5571: Effects of fish oil and Tamoxifen on preneoplastic lesion development and biomarkers of oxidative stress in the early stages of N-methyl-N-nitrosourea-induced rat mammary carcinogenesis Cancer Research. 71: 5571-5571. DOI: 10.1158/1538-7445.Am2011-5571  0.403
2011 Zhang S, Chen K, Sharma AK, Aliaga C, Lin J, Sun Y, Amin S, El-Bayoumy K. Abstract 5550: Identification and quantification of DNA adducts in the oral tissues of mice treated with the environmental carcinogen dibenzo[a,l]pyrene by LC-MS/MS Cancer Research. 71: 5550-5550. DOI: 10.1158/1538-7445.Am2011-5550  0.375
2011 Manni A, Xu H, Washington S, Aliaga C, Cooper TK, Richie JP, Prokopczyk B, Calcagnotto A, Trushin N, Hamilton C, Demers LM, Liao J, Verderame MF, El-Bayoumy K. Abstract 3710: Individual and combined effects of Tamoxifen and fish oil on mammary carcinogenesis in polyoma middle T transgenic mice Cancer Research. 71: 3710-3710. DOI: 10.1158/1538-7445.Am2011-3710  0.353
2011 Zhu Z, Jiang W, McGinley JN, Manni A, El-Bayoumy K, Thompson HJ. Abstract 3696: Effect of dietary omega-3/omega-6 ratio on mammary carcinogenesis, circulating biomarkers and molecular regulators in rats Cancer Research. 71: 3696-3696. DOI: 10.1158/1538-7445.Am2011-3696  0.392
2011 Chen K, Zhang S, Sharma AK, Aliaga C, Cooper T, Sun Y, Ahn K, Amin S, El-Bayoumy K. Abstract 1333: Carcinogenicity and formation of DNA adducts induced by dibenzo[a,l]pyrene (DB[a,l]P), an environmental pollutant and a tobacco smoke component, in the ovary of mouse Cancer Research. 71: 1333-1333. DOI: 10.1158/1538-7445.Am2011-1333  0.408
2010 Facompre ND, El-Bayoumy K, Sun YW, Pinto JT, Sinha R. 1,4-phenylenebis(methylene)selenocyanate, but not selenomethionine, inhibits androgen receptor and Akt signaling in human prostate cancer cells. Cancer Prevention Research (Philadelphia, Pa.). 3: 975-84. PMID 20606040 DOI: 10.1158/1940-6207.Capr-10-0054  0.329
2010 Manni A, Xu H, Washington S, Aliaga C, Cooper T, Richie JP, Bruggeman R, Prokopczyk B, Calcagnotto A, Trushin N, Mauger D, Verderame MF, El-Bayoumy K. The impact of fish oil on the chemopreventive efficacy of tamoxifen against development of N-methyl-N-nitrosourea-induced rat mammary carcinogenesis. Cancer Prevention Research (Philadelphia, Pa.). 3: 322-30. PMID 20179301 DOI: 10.1158/1940-6207.Capr-09-0173  0.368
2010 Desai D, Madhunapantula SV, Gowdahalli K, Sharma A, Chandagaludoreswamy R, El-Bayoumy K, Robertson GP, Amin S. Synthesis and characterization of a novel iNOS/Akt inhibitor Se,Se'-1,4-phenylenebis(1,2-ethanediyl)bisisoselenourea (PBISe)--against colon cancer. Bioorganic & Medicinal Chemistry Letters. 20: 2038-43. PMID 20153642 DOI: 10.1016/J.Bmcl.2009.09.071  0.336
2010 Facompre N, Sinha I, Pinto J, El-Bayoumy K, Sinha R. Abstract 574: 1,4-phenylenebis(methylene)selenocyanate (p-XSC) inhibits mammalian target of rapamycin complex 2 (mTORC2) signaling in prostate cancer cells Cancer Research. 70: 574-574. DOI: 10.1158/1538-7445.Am10-574  0.311
2010 Vanegas JE, Bidinotto LT, Pereira JS, Lopez R, Washington S, Xu H, Aliaga C, Russo IH, Manni A, El-Bayoumy K, Russo J. Abstract 5722: Effects of dietary omega-3 and omega-6 in the prevention of rat mammary cancer with tamoxifen Cancer Research. 70: 5722-5722. DOI: 10.1158/1538-7445.Am10-5722  0.306
2010 Das A, Richie J, Bortner J, Aliaga C, Stanley A, Stanley BA, El-Bayoumy K. Abstract 4589: Changes in proteomic profiles with age in male rats using the iTRAQ approach Cancer Research. 70: 4589-4589. DOI: 10.1158/1538-7445.Am10-4589  0.317
2010 Bortner JD, Richie J, Das A, Liao J, Umstead T, Stanley A, Stanley B, Belani C, El-Bayoumy K. Abstract 4572: Comparison of proteomic profiles in human plasma of smokers and nonsmokers using the iTRAQ approach Cancer Research. 70: 4572-4572. DOI: 10.1158/1538-7445.Am10-4572  0.32
2010 Zhu Z, McGinley JN, Jiang W, Manni A, El-Bayoumy K, Thompson HJ. Abstract 2873: Elucidation of dietary omega-6/omega-3 ratio effects on chemopreventive activity using mammographic density as a surrogate marker in rats Cancer Research. 70: 2873-2873. DOI: 10.1158/1538-7445.Am10-2873  0.364
2010 Chen K, Guttenplan JB, Aliaga C, Cooper T, Deltondo J, Kosinska W, Sharma AK, Sun Y, Zhang S, Jiang K, Bruggeman R, Amin S, El-Bayoumy K. Abstract 2455: The fjord region (±)-anti-dibenzo[a,l]pyrene-11,12-dihydrodiol-13,14-epoxides ((±)-anti-DB[a,l]PDE), is a powerful and specific inducer of squamous cell carcinoma in the oral cavity of mice Cancer Research. 70: 2455-2455. DOI: 10.1158/1538-7445.Am10-2455  0.358
2010 Guttenplan JB, Kosinska W, Zhao Z, Chen K, Aliaga C, Cooper T, Sun Y, Zhang S, Jiang K, Bruggeman R, Sharma AK, Amin S, El-Bayoumy K. Abstract 1968: Mutagenesis and carcinogenesis induced by dibenzo[ a,l ]pyrene in the mouse oral cavity: A potential new model for oral cancer Cancer Research. 70: 1968-1968. DOI: 10.1158/1538-7445.Am10-1968  0.399
2009 Sun YW, Guttenplan JB, Khmelnitsky M, Krzeminski J, Boyiri T, Amin S, El-Bayoumy K. Stereoselective metabolism of the environmental mammary carcinogen 6-nitrochrysene to trans-1,2-dihydroxy-1,2-dihydro-6-nitrochrysene by aroclor 1254-treated rat liver microsomes and their comparative mutation profiles in a laci mammary epithelial cell line. Chemical Research in Toxicology. 22: 1992-7. PMID 19886636 DOI: 10.1021/Tx9002897  0.307
2009 Boyiri T, Somiari RI, Russell S, Aliaga C, El-Bayoumy K. Proteomics of rat prostate lobes treated with 2-N-hydroxylamino-1-methyl-6-phenylimidazo[4,5-b]pyridine, 5alpha-dihydrotestosterone, individually and in combination. International Journal of Oncology. 35: 559-67. PMID 19639176 DOI: 10.3892/Ijo_00000367  0.336
2009 Das A, Bortner J, Desai D, Amin S, El-Bayoumy K. The selenium analog of the chemopreventive compound S,S'-(1,4-phenylenebis[1,2-ethanediyl])bisisothiourea is a remarkable inducer of apoptosis and inhibitor of cell growth in human non-small cell lung cancer. Chemico-Biological Interactions. 180: 158-64. PMID 19497413 DOI: 10.1016/J.Cbi.2009.03.003  0.38
2009 Chen KM, Sacks PG, Spratt TE, Lin JM, Boyiri T, Schwartz J, Richie JP, Calcagnotto A, Das A, Bortner J, Zhao Z, Amin S, Guttenplan J, El-Bayoumy K. Modulations of benzo[a]pyrene-induced DNA adduct, cyclin D1 and PCNA in oral tissue by 1,4-phenylenebis(methylene)selenocyanate. Biochemical and Biophysical Research Communications. 383: 151-5. PMID 19344691 DOI: 10.1016/J.Bbrc.2009.03.145  0.393
2008 He P, Borland MG, Zhu B, Sharma AK, Amin S, El-Bayoumy K, Gonzalez FJ, Peters JM. Effect of ligand activation of peroxisome proliferator-activated receptor-beta/delta (PPARbeta/delta) in human lung cancer cell lines. Toxicology. 254: 112-7. PMID 18950674 DOI: 10.1016/J.Tox.2008.09.023  0.309
2008 Sinha R, Pinto JT, Facompre N, Kilheffer J, Baatz JE, El-Bayoumy K. Effects of naturally occurring and synthetic organoselenium compounds on protein profiling in androgen responsive and androgen independent human prostate cancer cells. Nutrition and Cancer. 60: 267-75. PMID 18444160 DOI: 10.1080/01635580701630479  0.353
2008 Melikian AA, Chen KM, Li H, Sodum R, Fiala E, El-Bayoumy K. The role of nitric oxide on DNA damage induced by benzene metabolites. Oncology Reports. 19: 1331-7. PMID 18425395 DOI: 10.3892/Or.19.5.1331  0.326
2008 Trushin N, Leder G, El-Bayoumy K, Hoffmann D, Beger HG, Henne-Bruns D, Ramadani M, Prokopczyk B. The tobacco carcinogen NNK is stereoselectively reduced by human pancreatic microsomes and cytosols. Langenbeck's Archives of Surgery / Deutsche Gesellschaft FüR Chirurgie. 393: 571-9. PMID 18259773 DOI: 10.1007/S00423-007-0265-3  0.34
2007 Chen KM, Spratt TE, Stanley BA, De Cotiis DA, Bewley MC, Flanagan JM, Desai D, Das A, Fiala ES, Amin S, El-Bayoumy K. Inhibition of nuclear factor-kappaB DNA binding by organoselenocyanates through covalent modification of the p50 subunit. Cancer Research. 67: 10475-83. PMID 17974991 DOI: 10.1158/0008-5472.Can-07-2510  0.313
2007 Guttenplan J, Chen KM, Khmelnitsky M, Kosinska W, Hennessy J, Bruggeman R, Desai D, Amin S, Sun YW, Spratt TE, El-Bayoumy K. Effects of 1,4-phenylenebis(methylene)selenocyanate on mutagenesis and p53 protein expression in the tongue of lacI rats treated with 4-nitroquinoline-N-oxide. Mutation Research. 634: 146-55. PMID 17720616 DOI: 10.1016/J.Mrgentox.2007.07.005  0.393
2007 Sun YW, Herzog CR, Krzeminski J, Amin S, Perdew G, El-Bayoumy K. Effects of the environmental mammary carcinogen 6-nitrochrysene on p53 and p21(Cip1) protein expression and cell cycle regulation in MCF-7 and MCF-10A cells. Chemico-Biological Interactions. 170: 31-9. PMID 17678638 DOI: 10.1016/J.Cbi.2007.06.039  0.379
2007 Guttenplan JB, Zhao ZL, Kosinska W, Norman RG, Krzeminski J, Sun YW, Amin S, El-Bayoumy K. Comparative mutational profiles of the environmental mammary carcinogen, 6-nitrochrysene and its metabolites in a lacI mammary epithelial cell line. Carcinogenesis. 28: 2391-7. PMID 17602172 DOI: 10.1093/Carcin/Bgm142  0.337
2007 Chang SI, El-Bayoumy K, Sinha I, Trushin N, Stanley B, Pittman B, Prokopczyk B. 4-(Methylnitrosamino)-I-(3-pyridyl)-1-butanone enhances the expression of apolipoprotein A-I and Clara cell 17-kDa protein in the lung proteomes of rats fed a corn oil diet but not a fish oil diet. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 16: 228-35. PMID 17301254 DOI: 10.1158/1055-9965.Epi-06-0567  0.307
2007 Pinto JT, Sinha R, Papp K, Facompre ND, Desai D, El-Bayoumy K. Differential effects of naturally occurring and synthetic organoselenium compounds on biomarkers in androgen responsive and androgen independent human prostate carcinoma cells International Journal of Cancer. 120: 1410-1417. PMID 17205524 DOI: 10.1002/Ijc.22500  0.349
2006 Richie JP, Kleinman W, Desai DH, Das A, Amin SG, Pinto JT, El-Bayoumy K. The organoselenium compound 1,4-phenylenebis(methylene)selenocyanate inhibits 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced tumorgenesis and enhances glutathione-related antioxidant levels in A/J mouse lung. Chemico-Biological Interactions. 161: 93-103. PMID 16620795 DOI: 10.1016/J.Cbi.2006.03.005  0.392
2006 El-Bayoumy K, Sinha R, Pinto JT, Rivlin RS. Cancer chemoprevention by garlic and garlic-containing sulfur and selenium compounds. The Journal of Nutrition. 136: 864S-869S. PMID 16484582 DOI: 10.1093/Jn/136.3.864S  0.399
2006 El-Bayoumy K, Das A, Narayanan B, Narayanan N, Fiala ES, Desai D, Rao CV, Amin S, Sinha R. Molecular targets of the chemopreventive agent 1,4-phenylenebis (methylene)-selenocyanate in human non-small cell lung cancer. Carcinogenesis. 27: 1369-76. PMID 16399772 DOI: 10.1093/Carcin/Bgi328  0.386
2005 Chen KM, El-Bayoumy K, Hosey J, Cunningham J, Aliaga C, Melikian AA. Benzene increases protein-bound 3-nitrotyrosine in bone marrow of B6C3F1 mice. Chemico-Biological Interactions. 156: 81-91. PMID 16139254 DOI: 10.1016/J.Cbi.2005.07.005  0.308
2005 El-Bayoumy K, Sinha R. Molecular chemoprevention by selenium: a genomic approach. Mutation Research. 591: 224-36. PMID 16099479 DOI: 10.1016/J.Mrfmmm.2005.04.021  0.367
2005 Prokopczyk B, Leder G, Trushin N, Cunningham AJ, Akerkar S, Pittman B, Ramadani M, Straeter J, Beger HG, Henne-Bruns D, El-Bayoumy K. 4-Hydroxy-1-(3-pyridyl)-1-butanone, an indicator for 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced DNA damage, is not detected in human pancreatic tissue. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 14: 540-1. PMID 15734986 DOI: 10.1158/1055-9965.Epi-04-0626  0.345
2005 Sohn OS, Desai DH, Das A, Rodriguez JG, Amin SG, El-Bayoumy K. Comparative excretion and tissue distribution of selenium in mice and rats following treatment with the chemopreventive agent 1,4-phenylenebis(methylene)selenocyanate. Chemico-Biological Interactions. 151: 193-202. PMID 15733540 DOI: 10.1016/J.Cbi.2004.10.007  0.4
2005 Fiala ES, Sohn OS, Wang CX, Seibert E, Tsurutani J, Dennis PA, El-Bayoumy K, Sodum RS, Desai D, Reinhardt J, Aliaga C. Induction of preneoplastic lung lesions in guinea pigs by cigarette smoke inhalation and their exacerbation by high dietary levels of vitamins C and E. Carcinogenesis. 26: 605-12. PMID 15579485 DOI: 10.1093/Carcin/Bgh341  0.354
2004 El-Bayoumy K, Sharma AK, Lin JM, Krzeminski J, Boyiri T, King LC, Lambert G, Padgett W, Nesnow S, Amin S. Identification of 5-(deoxyguanosin-N2-yl)-1,2-dihydroxy-1,2- dihydro-6-aminochrysene as the major DNA lesion in the mammary gland of rats treated with the environmental pollutant 6-nitrochrysene Chemical Research in Toxicology. 17: 1591-1599. PMID 15606134 DOI: 10.1021/Tx049849+  0.358
2004 Sun YW, Guengerich FP, Sharma AK, Boyiri T, Amin S, el-Bayoumy K. Human cytochromes P450 1A1 and 1B1 catalyze ring oxidation but not nitroreduction of environmental pollutant mononitropyrene isomers in primary cultures of human breast cells and cultured MCF-10A and MCF-7 cell lines. Chemical Research in Toxicology. 17: 1077-85. PMID 15310239 DOI: 10.1021/Tx049889D  0.318
2004 El-Bayoumy K, Sinha R. Mechanisms of mammary cancer chemoprevention by organoselenium compounds. Mutation Research. 551: 181-97. PMID 15225592 DOI: 10.1016/J.Mrfmmm.2004.02.023  0.417
2004 Guttenplan JB, Spratt TE, Khmelnitsky M, Kosinska W, Desai D, El-Bayoumy K. Effects of 3H-1,2-dithiole-3-thione, 1,4-phenylenebis(methylene)selenocyanate, and selenium-enriched yeast individually and in combination on benzo[a]pyrene-induced mutagenesis in oral tissue and esophagus in lacZ mice. Mutation Research. 559: 199-210. PMID 15066587 DOI: 10.1016/J.Mrgentox.2004.02.002  0.348
2004 Sinha R, El-Bayoumy K. Apoptosis is a critical cellular event in cancer chemoprevention and chemotherapy by selenium compounds. Current Cancer Drug Targets. 4: 13-28. PMID 14965264 DOI: 10.2174/1568009043481614  0.362
2004 Boyiri T, Guttenplan J, Khmelnitsky M, Kosinska W, Lin JM, Desai D, Amin S, Pittman B, El-Bayoumy K. Mammary carcinogenesis and molecular analysis of in vivo cII gene mutations in the mammary tissue of female transgenic rats treated with the environmental pollutant 6-nitrochrysene. Carcinogenesis. 25: 637-43. PMID 14656939 DOI: 10.1093/Carcin/Bgh040  0.35
2003 Das A, Desai D, Pittman B, Amin S, El-Bayoumy K. Comparison of the Chemopreventive Efficacies of 1,4-phenylenebis(methylene)selenocyanate and Selenium-Enriched Yeast on 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone Induced Lung Tumorigenesis in A/ J Mouse Nutrition and Cancer. 46: 179-185. PMID 14690794 DOI: 10.1207/S15327914Nc4602_11  0.388
2003 Bartram HP, Krüger S, Dusel G, El-Bayoumy K, Upadhyaya P, Scheppach W. Antiproliferative effect of 1,4-phenylenebis(methylene)selenocyanate (p-XSC) on colonic epithelium of patients with adenomatous polyps in vitro. European Journal of Cancer Prevention. 12: 463-468. PMID 14639123 DOI: 10.1097/00008469-200312000-00004  0.376
2003 El-Bayoumy K, Das A, Boyiri T, Desai D, Sinha R, Pittman B, Amin S. Comparative action of 1,4-phenylenebis(methylene)selenocyanate and its metabolites against 7,12-dimethylbenz[a]anthracene-DNA adduct formation in the rat and cell proliferation in rat mammary tumor cells. Chemico-Biological Interactions. 146: 179-90. PMID 14597131 DOI: 10.1016/J.Cbi.2003.08.004  0.447
2003 El-Bayoumy K, Narayanan BA, Desai DH, Narayanan NK, Pittman B, Amin SG, Schwartz J, Nixon DW. Elucidation of molecular targets of mammary cancer chemoprevention in the rat by organoselenium compounds using cDNA microarray. Carcinogenesis. 24: 1505-14. PMID 12844480 DOI: 10.1093/Carcin/Bgg103  0.419
2002 El-Bayoumy K, Desai D, Boyiri T, Rosa J, Krzeminski J, Sharma AK, Pittman B, Amin S. Comparative tumorigenicity of the environmental pollutant 6-nitrochrysene and its metabolites in the rat mammary gland. Chemical Research in Toxicology. 15: 972-8. PMID 12119009 DOI: 10.1021/Tx020019A  0.414
2002 Desai D, Sharma AK, Lin JM, Krzeminski J, Pimentel M, El-Bayoumy K, Nesnow S, Amin S. Synthesis, in vitro metabolism, cell transformation, mutagenicity, and DNA adduction of dibenzo[c,mno]chrysene. Chemical Research in Toxicology. 15: 964-71. PMID 12119008 DOI: 10.1021/Tx0200111  0.365
2002 Guttenplan JB, Kosinska W, von Pressentin Md, Rosa J, El-Bayoumy K. Effects of 1,4-phenylenebis(methylene)selenocyanate (p-XSC) and vitamin E on 4-nitroquinoline-N-oxide (4-NQO)-induced mutagenesis in lacZ mouse upper aerodigestive tissue. Mutation Research. 518: 85-93. PMID 12063070 DOI: 10.1016/S1383-5718(02)00082-7  0.351
2002 El-Bayoumy K, Rose DP, Papanikolaou N, Leszczynska J, Swamy MV, Rao CV. Cyclooxygenase-2 expression influences the growth of human large and small cell lung carcinoma lines in athymic mice: impact of an organoselenium compound on growth regulation. International Journal of Oncology. 20: 557-561. PMID 11836568 DOI: 10.3892/Ijo.20.3.557  0.38
2002 Li JJ, Papa D, Davis MF, Weroha SJ, Aldaz CM, El-Bayoumy K, Ballenger J, Tawfik O, Li SA. Ploidy differences between hormone- and chemical carcinogen-induced rat mammary neoplasms: comparison to invasive human ductal breast cancer. Molecular Carcinogenesis. 33: 56-65. PMID 11807958 DOI: 10.1002/Mc.10022  0.328
2002 Desai D, Sharma AK, Lin J, El-Bayoumy K, Amin S, Pimentel M, Nesnow S. Synthesis, in Vitro Metabolism, Mutagenicity, and DNA-Adduction of Naphtho[1,2- e ]pyrene Polycyclic Aromatic Compounds. 22: 267-276. DOI: 10.1080/10406630290026911  0.35
2002 Desai D, Lin G, Morimoto H, Williams PG, El-Bayoumy K, Amin S. Synthesis of (plus or minus) [5-{sup 3}H] N'-Nitrosoanatabine, a tobacco-specific nitrosamine Journal of Labelled Compounds and Radiopharmaceuticals. 45: 1133-1141. DOI: 10.1002/Jlcr.630  0.31
2001 El-Bayoumy K, Rao CV, Reddy BS. Multiorgan sensitivity to anticarcinogenesis by the organoselenium 1,4-phenylenebis(methylene)selenocyanate. Nutrition and Cancer. 40: 18-27. PMID 11799918 DOI: 10.1207/S15327914Nc401_6  0.331
2001 El-Bayoumy K. The protective role of selenium on genetic damage and on cancer Mutation Research. 475: 123-139. PMID 11295158 DOI: 10.1016/S0027-5107(01)00075-6  0.362
2000 Krzeminski J, Desai D, Lin J, Serebryany V, El-Bayoumy K, Amin S. Synthesis of anti-1,2-dihydroxy-3,4-epoxy-1,2,3, 4-tetrahydro-6-nitrochrysene and its reaction with 2'-deoxyguanosine- 5'-monophosphate, 2'-deoxyadenosine-5'-monophosphate, and calf thymus DNA in vitro. Chemical Research in Toxicology. 13: 1143-1148. PMID 11087436 DOI: 10.1021/Tx000104N  0.364
2000 Prokopczyk B, Rosa JG, Desai D, Amin S, Sohn OS, Fiala ES, El-Bayoumy K. Chemoprevention of lung tumorigenesis induced by a mixture of benzo(a)pyrene and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone by the organoselenium compound 1,4-phenylenebis(methylene)selenocyanate. Cancer Letters. 161: 35-46. PMID 11078911 DOI: 10.1016/S0304-3835(00)00590-5  0.397
2000 El-Bayoumy K, Chae YH, Rosa JG, Williams LK, Desai D, Amin S, Fiala E. The effects of 1-nitropyrene, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine and 7,12-dimethylbenz[a]anthracene on 8-hydroxy-2'-deoxyguanosine levels in the rat mammary gland and modulation by dietary 1,4-phenylenebis(methylene) selenocyanate. Cancer Letters. 151: 7-13. PMID 10766416 DOI: 10.1016/S0304-3835(99)00391-2  0.405
2000 Rao CV, Cooma I, Rodriguez JGR, Simi B, El-Bayoumy K, Reddy BS. Chemoprevention of familial adenomatous polyposis development in the APCmin mouse model by 1,4-phenylene bis(methylene)selenocyanate Carcinogenesis. 21: 617-621. PMID 10753194 DOI: 10.1093/Carcin/21.4.617  0.398
2000 Pressentin MdMv, El-Bayoumy K, Guttenplan JB. Mutagenic activity of 4-nitroquinoline-N-oxide in upper aerodigestive tissue in lacZ mice (Muta™Mouse) and the effects of 1,4-phenylenebis(methylene)selenocyanate Mutation Research-Genetic Toxicology and Environmental Mutagenesis. 466: 71-78. PMID 10751728 DOI: 10.1016/S1383-5718(00)00005-X  0.393
2000 Rao CV, Simi B, Hirose Y, Upadhyaya P, El-Bayoumy K, Reddy BS. Mechanisms in the chemoprevention of colon cancer: modulation of protein kinase C, tyrosine protein kinase and diacylglycerol kinase activities by 1,4-phenylenebis-(methylene)selenocyanate and impact of low-fat diet. International Journal of Oncology. 16: 519-546. PMID 10675484 DOI: 10.3892/Ijo.16.3.519  0.378
2000 Sugie S, Tanaka T, El-Bayoumy K. Chemoprevention of Carcinogenesis by Organoselenium Compounds Journal of Health Science. 46: 422-425. DOI: 10.1248/Jhs.46.422  0.405
2000 Bartram H, Krueger S, Dusel G, El-Bayoumy K, Upadhyaya P, Burgstaller M, Scheppach W, Kasper H. Antiproliferative effect of 1,4-phenylenebis-(methylene)selenocyanate (p-XSC) on colonic epithelium of adenoma patients in vitro Gastroenterology. 118. DOI: 10.1016/S0016-5085(00)81396-7  0.307
1999 Melikian AA, Sun P, Prokopczyk B, El-Bayoumy K, Hoffmann D, Wang X, Waggoner SE. Identification of benzo[a]pyrene metabolites in cervical mucus and DNA adducts in cervical tissues in humans by gas chromatography-mass spectrometry. Cancer Letters. 146: 127-134. PMID 10656617 DOI: 10.1016/S0304-3835(99)00203-7  0.317
1999 Melikian AA, Wang X, Waggoner SE, Hoffmann D, El-Bayoumy K. Comparative response of normal and of human papillomavirus-16 immortalized human epithelial cervical cells to benzo[a]pyrene. Oncology Reports. 6: 1371-1376. PMID 10523714 DOI: 10.3892/Or.6.6.1371  0.307
1999 Sohn OS, Fiala ES, Upadhyaya P, Chae Y, El-Bayoumy K. Comparative effects of phenylenebis(methylene)selenocyanate isomers on xenobiotic metabolizing enzymes in organs of female CD rats. Carcinogenesis. 20: 615-621. PMID 10223189 DOI: 10.1093/Carcin/20.4.615  0.366
1999 Chae YH, Ji BY, Lin JM, Fu PP, Cho BP, El-Bayoumy K. Nitroreduction of 4-nitropyrene is primarily responsible for DNA adduct formation in the mammary gland of female CD rats. Chemical Research in Toxicology. 12: 180-6. PMID 10027796 DOI: 10.1021/Tx9802318  0.337
1998 Rosa JG, Prokopczyk B, Desai DH, Amin SG, El-Bayoumy K. Elevated 8-hydroxy-2'-deoxyguanosine levels in lung DNA of A/J mice and F344 rats treated with 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and inhibition by dietary 1,4-phenylenebis(methylene)selenocyanate. Carcinogenesis. 19: 1783-8. PMID 9806159 DOI: 10.1093/Carcin/19.10.1783  0.4
1998 El-Bayoumy K, Upadhyaya P, Sohn OS, Rosa JG, Fiala ES. Synthesis and excretion profile of 1,4-[14C]phenylenebis(methylene)selenocyanate in the rat. Carcinogenesis. 19: 1603-1607. PMID 9771931 DOI: 10.1093/Carcin/19.9.1603  0.378
1998 Upadhyaya P, El-Bayoumy K. Effect of dietary soy protein isolate, genistein, and 1,4-phenylenebis(methylene)selenocyanate on DNA binding of 7,12-dimethylbenz[a]anthracene in mammary glands of CD rats Oncology Reports. 5: 1541-1545. PMID 9769402 DOI: 10.3892/Or.5.6.1541  0.378
1998 Kawamori T, El-Bayoumy K, Ji B-, Rodriguez JGR, Rao CV, Reddy BS. Evaluation of benzyl selenocyanate glutathione conjugate for potential chemopreventive properties in colon carcinogenesis. International Journal of Oncology. 13: 29-34. PMID 9625800 DOI: 10.3892/Ijo.13.1.29  0.403
1998 Fiala ES, Staretz ME, Pandya GA, El-Bayoumy K, Hamilton SR. Inhibition of DNA cytosine methyltransferase by chemopreventive selenium compounds, determined by an improved assay for DNA cytosine methyltransferase and DNA cytosine methylation Carcinogenesis. 19: 597-604. PMID 9600343 DOI: 10.1093/Carcin/19.4.597  0.368
1997 El-Bayoumy K, Chung F-, Richie J, Reddy BS, Cohen L, Weisburger J, Wynder EL. Dietary control of cancer. Experimental Biology and Medicine. 216: 211-223. PMID 9349690 DOI: 10.3181/00379727-216-44171  0.345
1997 Prokopczyk B, Amin S, Desai DH, Kurtzke C, Upadhyaya P, El-Bayoumy K. Effects of 1,4-phenylenebis(methylene)selenocyanate and selenomethionine on 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced tumorigenesis in A/J mouse lung. Carcinogenesis. 18: 1855-1857. PMID 9328187 DOI: 10.1093/Carcin/18.9.1855  0.368
1997 Fiala ES, Sohn OS, Li H, El-Bayoumy K, Sodum RS. Inhibition of 2-nitropropane-induced rat liver DNA and RNA damage by benzyl selenocyanate Carcinogenesis. 18: 1809-1815. PMID 9328179 DOI: 10.1093/Carcin/18.9.1809  0.328
1997 Chae Y-, Upadhyaya P, Ji B-, Fu PP, El-Bayoumy K. Comparative metabolism and DNA binding of 1-, 2-, and 4-nitropyrene in rats Mutation Research. 376: 21-28. PMID 9202734 DOI: 10.1016/S0027-5107(97)00021-3  0.319
1997 Reddy BS, Rivenson A, El-Bayoumy K, Upadhyaya P, Pittman B, Rao CV. Chemoprevention of colon cancer by organoselenium compounds and impact of high- or low-fat diets Journal of the National Cancer Institute. 89: 506-512. PMID 9086007 DOI: 10.1093/Jnci/89.7.506  0.374
1996 Hecht SS, Rivenson A, Amin S, Krzeminski J, el-Bayoumy K, Reddy BS, Kurtzke C, La Voie EJ. Mammary carcinogenicity of diol epoxide metabolites of benzo[j]fluoranthene in female CD rats. Cancer Letters. 106: 251-5. PMID 8844980 DOI: 10.1016/0304-3835(96)04328-5  0.357
1996 Adler V, Pincus MR, Posner S, Upadhyaya P, El-Bayoumy K, Ronai Z. Effects of chemopreventive selenium compounds on Jun N-kinase activities. Carcinogenesis. 17: 1849-54. PMID 8824505 DOI: 10.1093/Carcin/17.9.1849  0.344
1996 Prokopczyk B, Cox JE, Upadhyaya P, Amin S, Desai D, Hoffmann D, el-Bayoumy K. Effects of dietary 1,4-phenylenebis(methylene)selenocyanate on 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced DNA adduct formation in lung and liver of A/J mice and F344 rats. Carcinogenesis. 17: 749-53. PMID 8625486 DOI: 10.1093/Carcin/17.4.749  0.387
1996 Amin S, Desai D, El-Bayoumy K, Rivenson A, Hecht SS. Tumorigenicity of Fjord Region Diol Epoxides of Polycyclic Aromatic Hydrocarbons Polycyclic Aromatic Compounds. 11: 365-371. DOI: 10.1080/10406639608544688  0.31
1995 el-Bayoumy K, Johnson B, Roy AK, Upadhyaya P, Partian S, Hecht SS. Development of methods to monitor exposure to 1-nitropyrene. Environmental Health Perspectives. 31-7. PMID 7889855 DOI: 10.1289/Ehp.94102S631  0.358
1995 el-Bayoumy K, Chae YH, Upadhyaya P, Rivenson A, Kurtzke C, Reddy B, Hecht SS. Comparative tumorigenicity of benzo[a]pyrene, 1-nitropyrene and 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine administered by gavage to female CD rats. Carcinogenesis. 16: 431-4. PMID 7859378 DOI: 10.1093/Carcin/16.2.431  0.372
1995 Hecht SS, Amin S, Lin JM, Rivenson A, Kurtzke C, el-Bayoumy K. Mammary carcinogenicity in female CD rats of a diol epoxide metabolite of fluoranthene, a commonly occurring environmental pollutant. Carcinogenesis. 16: 1433-5. PMID 7788865 DOI: 10.1093/Carcin/16.6.1433  0.373
1995 Amin S, Krzeminski J, Rivenson A, Kurtzke C, Hecht SS, el-Bayoumy K. Mammary carcinogenicity in female CD rats of fjord region diol epoxides of benzo[c]phenanthrene, benzo[g]chrysene and dibenzo[a,l]pyrene. Carcinogenesis. 16: 1971-4. PMID 7634428 DOI: 10.1093/Carcin/16.8.1971  0.341
1995 Ronai Z, Tillotson JK, Traganos F, Darzynkiewicz Z, Conaway CC, Upadhyaya P, el-Bayoumy K. Effects of organic and inorganic selenium compounds on rat mammary tumor cells. International Journal of Cancer. 63: 428-34. PMID 7591244 DOI: 10.1002/Ijc.2910630322  0.388
1994 Ip C, El-Bayoumy K, Upadhyaya P, Ganther H, Vadhanavikit S, Thompson H. Comparative effect of inorganic and organic selenocyanate derivatives in mammary cancer chemoprevention Carcinogenesis. 15: 187-192. PMID 8313507 DOI: 10.1093/Carcin/15.2.187  0.403
1994 Thompson HJ, Wilson A, Lu J, Singh M, Jiang C, Upadhyaya P, el-Bayoumy K, Ip C. Comparison of the effects of an organic and an inorganic form of selenium on a mammary carcinoma cell line. Carcinogenesis. 15: 183-6. PMID 8313506 DOI: 10.1093/Carcin/15.2.183  0.368
1994 el-Bayoumy K, Johnson B, Partian S, Upadhyaya P, Hecht SS. In vivo binding of 1-nitropyrene to albumin in the rat. Carcinogenesis. 15: 119-23. PMID 8293536 DOI: 10.1093/Carcin/15.1.119  0.357
1994 Yamazaki H, Mimura M, Oda Y, Gonzalez FJ, el-Bayoumy K, Chae YH, Guengerich FP, Shimada T. Activation of trans-1,2-dihydro-1,2-dihydroxy-6-aminochrysene to genotoxic metabolites by rat and human cytochromes P450. Carcinogenesis. 15: 465-70. PMID 8118930 DOI: 10.1093/Carcin/15.3.465  0.327
1993 el-Bayoumy K, Upadhyaya P, Desai DH, Amin S, Hecht SS. Inhibition of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone tumorigenicity in mouse lung by the synthetic organoselenium compound, 1,4-phenylenebis(methylene)selenocyanate. Carcinogenesis. 14: 1111-3. PMID 8508496 DOI: 10.1093/Carcin/14.6.1111  0.383
1993 Swenson DH, el-Bayoumy K, Shuie GH, Hecht SS, Fiala E, Kadlubar FF, Freeman JP. Synthesis of N-(purin-8-yl)arylamines. Chemical Research in Toxicology. 6: 480-5. PMID 8374045 DOI: 10.1021/Tx00034A014  0.328
1993 el-Bayoumy K, Desai D, Upadhyaya P, Amin S, Hecht SS. Comparative tumorigenicity of nitrochrysene isomers in newborn mice. Carcinogenesis. 13: 2271-5. PMID 1473233 DOI: 10.1093/Carcin/13.12.2271  0.34
1992 el-Bayoumy K, Shiue GH, Hecht SS. Metabolism and DNA binding of 1-nitropyrene and 1-nitrosopyrene in newborn mice. Chemical Research in Toxicology. 1: 243-7. PMID 2979739 DOI: 10.1021/Tx00004A010  0.34
1992 El-Bayoumy K. Environmental carcinogens that may be involved in human breast cancer etiology. Chemical Research in Toxicology. 5: 585-590. PMID 1445997 DOI: 10.1021/Tx00029A001  0.302
1992 Conaway CC, Upadhyaya P, Meschter CL, Kurtzke C, Marcus LA, el-Bayoumy K. Subchronic toxicity of benzyl selenocyanate and 1,4-phenylenebis(methylene)selenocyanate in F344 rats. Fundamental and Applied Toxicology : Official Journal of the Society of Toxicology. 19: 563-74. PMID 1426715 DOI: 10.1016/0272-0590(92)90095-Y  0.311
1991 El-Bayoumy K, Upadhyaya P, Date V, Sohn OS, Fiala ES, Reddy B. Metabolism of [14C]benzyl selenocyanate in the F344 rat. Chemical Research in Toxicology. 4: 560-565. PMID 1793806 DOI: 10.1021/Tx00023A012  0.349
1989 el-Bayoumy K, Shiue GH, Hecht SS. Comparative tumorigenicity of 6-nitrochrysene and its metabolites in newborn mice. Carcinogenesis. 10: 369-72. PMID 2912588 DOI: 10.1093/Carcin/10.2.369  0.357
1989 Roy AK, el-Bayoumy K, Hecht SS. 32P-postlabeling analysis of 1-nitropyrene-DNA adducts in female Sprague-Dawley rats. Carcinogenesis. 10: 195-8. PMID 2910523 DOI: 10.1093/Carcin/10.1.195  0.384
1989 el-Bayoumy K, Shiue GH, Amin S, Hecht SS. The effects of bay-region methyl substitution on 6-nitrochrysene mutagenicity in Salmonella typhimurium and tumorigenicity in newborn mice. Carcinogenesis. 10: 1685-9. PMID 2670305 DOI: 10.1093/Carcin/10.9.1685  0.361
1989 el-Bayoumy K, Delclos KB, Heflich RH, Walker R, Shiue GH, Hecht SS. Mutagenicity, metabolism and DNA adduct formation of 6-nitrochrysene in Salmonella typhimurium. Mutagenesis. 4: 235-40. PMID 2659942 DOI: 10.1093/Mutage/4.3.235  0.341
1989 Nayini J, El-Bayoumy K, Sugie S, Cohen LA, Reddy BS. Chemoprevention of experimental mammary carcinogenesis by the synthetic organoselenium compound, benzylselenocyanate, in rats. Carcinogenesis. 10: 509-512. PMID 2538274 DOI: 10.1093/Carcin/10.3.509  0.392
1989 Sugie S, Reddy BS, El-Bayoumy K, Tanaka T. Inhibition by dietary benzylselenocyanate of hepatocarcinogenesis induced by azoxymethane in Fischer 344 rats. Japanese Journal of Cancer Research. 80: 952-957. PMID 2515179 DOI: 10.1111/J.1349-7006.1989.Tb01632.X  0.312
1987 Shiue GH, el-Bayoumy K, Hecht SS. Comparative metabolism and DNA binding of 6-nitro-5-methylchrysene and 5-methylchrysene. Carcinogenesis. 8: 1327-31. PMID 3621469 DOI: 10.1093/Carcin/8.9.1327  0.337
1986 el-Bayoumy K, Amin S, Hecht SS. Effects of 6-nitro substitution on 5-methylchrysene tumorigenicity, mutagenicity and metabolism. Carcinogenesis. 7: 673-6. PMID 3509952 DOI: 10.1093/Carcin/7.4.673  0.354
1985 Tanaka T, Reddy BS, El-Bayoumy K. Inhibition by dietary organoselenium, p-methoxybenzene-selenol, of hepatocarcinogenesis induced by azoxymethane in rats. Japanese Journal of Cancer Research. 76: 462-467. DOI: 10.20772/Cancersci1985.76.6_462  0.385
1985 Reddy BS, Tanaka T, El-Bayoumy K. Inhibitory Effect of Dietary p-Methoxybenzeneselenol on Azoxymethane-Induced Colon and Kidney Carcinogenesis in Female F344 Rats Journal of the National Cancer Institute. 74: 1325-1328. DOI: 10.1093/Jnci/74.6.1325  0.342
1984 El-Bayoumy K, Hecht SS, Sackl T, Stoner GD. Tumorigenicity and metabolism of 1-nitropyrene in A/J mice. Carcinogenesis. 5: 1449-52. PMID 6488469 DOI: 10.1093/Carcin/5.11.1449  0.326
1984 El-Bayoumy K, Reddy B, Hecht SS. Identification of ring oxidized metabolites of 1-nitropyrene in the feces and urine of germfree F344 rats. Carcinogenesis. 5: 1371-3. PMID 6488459 DOI: 10.1093/Carcin/5.10.1371  0.316
1983 El-Bayoumy K, Sharma C, Louis YM, Reddy B, Hecht SS. The role of intestinal microflora in the metabolic reduction of 1-nitropyrene to 1-aminopyrene in conventional and germfree rats and in humans. Cancer Letters. 19: 311-6. PMID 6688375 DOI: 10.1016/0304-3835(83)90100-3  0.319
1983 Hecht SS, El-Bayoumy K, Rivenson A, Fiala ES. Bioassay for carcinogenicity of 3,2'-dimethyl-4-nitrosobiphenyl, O-nitrosotoluene, nitrosobenzene and the corresponding amines in Syrian golden hamsters. Cancer Letters. 20: 349-54. PMID 6627231 DOI: 10.1016/0304-3835(83)90034-4  0.302
1982 Hecht SS, El-Bayoumy K, Rivenson A, Fiala E. Comparative carcinogenicity of o-toluidine hydrochloride and o-nitrosotoluene in F-344 rats. Cancer Letters. 16: 103-8. PMID 7116337 DOI: 10.1016/0304-3835(82)90097-0  0.306
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