| Year |
Citation |
Score |
| 2023 |
Varma E, Burghaus J, Schwarzl T, Sekaran T, Gupta P, Górska AA, Hofmann C, Stroh C, Jürgensen L, Kamuf-Schenk V, Li X, Medert R, Leuschner F, Kmietczyk V, Freichel M, ... ... Hentze MW, et al. Translational control of Ybx1 expression regulates cardiac function in response to pressure overload in vivo. Basic Research in Cardiology. 118: 25. PMID 37378715 DOI: 10.1007/s00395-023-00996-1 |
0.337 |
|
| 2021 |
Bauer TA, Horvat NK, Marques O, Chocarro S, Mertens C, Colucci S, Schmitt S, Carrella LM, Morsbach S, Koynov K, Fenaroli F, Blümler P, Jung M, Sotillo R, Hentze MW, et al. Core Cross-Linked Polymeric Micelles for Specific Iron Delivery: Inducing Sterile Inflammation in Macrophages. Advanced Healthcare Materials. e2100385. PMID 34137217 DOI: 10.1002/adhm.202100385 |
0.339 |
|
| 2021 |
Riechert E, Kmietczyk V, Stein F, Schwarzl T, Sekaran T, Jürgensen L, Kamuf-Schenk V, Varma E, Hofmann C, Rettel M, Gür K, Ölschläger J, Kühl F, Martin J, Ramirez-Pedraza M, ... ... Hentze MW, et al. Identification of dynamic RNA-binding proteins uncovers a Cpeb4-controlled regulatory cascade during pathological cell growth of cardiomyocytes. Cell Reports. 35: 109100. PMID 33979607 DOI: 10.1016/j.celrep.2021.109100 |
0.351 |
|
| 2020 |
Iserman C, Desroches Altamirano C, Jegers C, Friedrich U, Zarin T, Fritsch AW, Mittasch M, Domingues A, Hersemann L, Jahnel M, Richter D, Guenther UP, Hentze MW, Moses AM, Hyman AA, et al. Condensation of Ded1p Promotes a Translational Switch from Housekeeping to Stress Protein Production. Cell. PMID 32359423 DOI: 10.1016/J.Cell.2020.04.009 |
0.356 |
|
| 2020 |
Backlund M, Stein F, Rettel M, Schwarzl T, Perez-Perri JI, Brosig A, Zhou Y, Neu-Yilik G, Hentze MW, Kulozik AE. Plasticity of nuclear and cytoplasmic stress responses of RNA-binding proteins. Nucleic Acids Research. PMID 32313943 DOI: 10.1093/Nar/Gkaa256 |
0.366 |
|
| 2020 |
Büscher M, Horos R, Hentze MW. 'High vault-age': non-coding RNA control of autophagy. Open Biology. 10: 190307. PMID 32070232 DOI: 10.1098/Rsob.190307 |
0.358 |
|
| 2019 |
Dziuba D, Hoffmann JE, Hentze MW, Schultz C. A genetically encoded diazirine analogue for RNA-protein photocrosslinking. Chembiochem : a European Journal of Chemical Biology. PMID 31658407 DOI: 10.1002/Cbic.201900559 |
0.398 |
|
| 2019 |
Cooke A, Schwarzl T, Huppertz I, Kramer G, Mantas P, Alleaume AM, Huber W, Krijgsveld J, Hentze MW. The RNA-Binding Protein YBX3 Controls Amino Acid Levels by Regulating SLC mRNA Abundance. Cell Reports. 27: 3097-3106.e5. PMID 31189097 DOI: 10.1016/J.Celrep.2019.05.039 |
0.401 |
|
| 2019 |
Horos R, Büscher M, Sachse C, Hentze MW. Vault RNA emerges as a regulator of selective autophagy. Autophagy. PMID 31006338 DOI: 10.1080/15548627.2019.1609861 |
0.355 |
|
| 2019 |
Vinchi F, Porto G, Simmelbauer A, Altamura S, Passos ST, Garbowski M, Silva AMN, Spaich S, Seide SE, Sparla R, Hentze MW, Muckenthaler MU. Atherosclerosis is aggravated by iron overload and ameliorated by dietary and pharmacological iron restriction. European Heart Journal. PMID 30903157 DOI: 10.1093/Eurheartj/Ehz112 |
0.458 |
|
| 2019 |
Horos R, Büscher M, Kleinendorst R, Alleaume AM, Tarafder AK, Schwarzl T, Dziuba D, Tischer C, Zielonka EM, Adak A, Castello A, Huber W, Sachse C, Hentze MW. The Small Non-coding Vault RNA1-1 Acts as a Riboregulator of Autophagy. Cell. 176: 1054-1067.e12. PMID 30773316 DOI: 10.1016/J.Cell.2019.01.030 |
0.37 |
|
| 2019 |
Trendel J, Schwarzl T, Horos R, Prakash A, Bateman A, Hentze MW, Krijgsveld J. The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest. Cell. 176: 391-403.e19. PMID 30528433 DOI: 10.1016/J.Cell.2018.11.004 |
0.36 |
|
| 2019 |
Colucci S, Altamura S, Hentze M, Muckenthaler MU. Sensing of Liver Iron Content Requires Cell-Cell Communication between Hepatocytes and Liver Sinusoidal Endothelial Cells Blood. 134: 432-432. DOI: 10.1182/Blood-2019-125586 |
0.326 |
|
| 2018 |
Perez-Perri JI, Rogell B, Schwarzl T, Stein F, Zhou Y, Rettel M, Brosig A, Hentze MW. Discovery of RNA-binding proteins and characterization of their dynamic responses by enhanced RNA interactome capture. Nature Communications. 9: 4408. PMID 30352994 DOI: 10.1038/S41467-018-06557-8 |
0.364 |
|
| 2018 |
Kwon E, Todorova K, Wang J, Horos R, Lee KK, Neel VA, Negri GL, Sorensen PH, Lee SW, Hentze MW, Mandinova A. The RNA-binding protein YBX1 regulates epidermal progenitors at a posttranscriptional level. Nature Communications. 9: 1734. PMID 29712925 DOI: 10.1038/S41467-018-04092-0 |
0.463 |
|
| 2018 |
Hentze MW, Castello A, Schwarzl T, Preiss T. A brave new world of RNA-binding proteins. Nature Reviews. Molecular Cell Biology. PMID 29339797 DOI: 10.1038/Nrm.2017.130 |
0.382 |
|
| 2018 |
Altamura S, Colucci S, Schmidt J, Muedder K, Neves J, Hentze M, Muckenthaler MU. Hepatocyte Iron Content Controls BMP6-Dependent Hepcidin Regulation Blood. 132: 3626-3626. DOI: 10.1182/Blood-2018-99-116109 |
0.47 |
|
| 2017 |
Vinchi F, Sparla R, Simmelbauer A, Altamura S, Speich S, Galy B, Hentze MW, Muckenthaler MU. Low-iron diet and chelation therapy rescue severe atherosclerosis associated with high circulating iron levels. Atherosclerosis. 263: e15-e16. PMID 29365590 DOI: 10.1016/J.Atherosclerosis.2017.06.076 |
0.422 |
|
| 2017 |
Costa da Silva M, Breckwoldt MO, Vinchi F, Correia MP, Stojanovic A, Thielmann CM, Meister M, Muley T, Warth A, Platten M, Hentze MW, Cerwenka A, Muckenthaler MU. Iron Induces Anti-tumor Activity in Tumor-Associated Macrophages. Frontiers in Immunology. 8: 1479. PMID 29167669 DOI: 10.3389/Fimmu.2017.01479 |
0.357 |
|
| 2017 |
Castello A, Frese CK, Fischer B, Järvelin AI, Horos R, Alleaume AM, Foehr S, Curk T, Krijgsveld J, Hentze MW. Identification of RNA-binding domains of RNA-binding proteins in cultured cells on a system-wide scale with RBDmap. Nature Protocols. 12: 2447-2464. PMID 29095441 DOI: 10.1038/Nprot.2017.106 |
0.377 |
|
| 2017 |
Quintas A, Pérez-Núñez D, Sánchez EG, Nogal ML, Hentze MW, Castelló A, Revilla Y. Characterization of the African swine fever virus decapping enzyme during infection. Journal of Virology. PMID 29021398 DOI: 10.1128/Jvi.00990-17 |
0.403 |
|
| 2017 |
Neu-Yilik G, Raimondeau E, Eliseev B, Yeramala L, Amthor B, Deniaud A, Huard K, Kerschgens K, Hentze MW, Schaffitzel C, Kulozik AE. Dual function of UPF3B in early and late translation termination. The Embo Journal. PMID 28899899 DOI: 10.15252/Embj.201797079 |
0.417 |
|
| 2017 |
Luscieti S, Galy B, Gutierrez L, Reinke M, Couso J, Shvartsman M, Di Pascale A, Witke W, Hentze MW, Pilo Boyl P, Sanchez M. The actin binding protein profilin 2 is a novel regulator of iron homeostasis. Blood. PMID 28774878 DOI: 10.1182/Blood-2016-11-754382 |
0.563 |
|
| 2017 |
da Silva AR, Neves J, Mleczko-Sanecka K, Tandon A, Sauer SW, Hentze MW, Muckenthaler MU. Cellular citrate levels establish a regulatory link between energy metabolism and the hepatic iron hormone hepcidin. Journal of Molecular Medicine (Berlin, Germany). PMID 28585096 DOI: 10.1007/S00109-017-1551-3 |
0.428 |
|
| 2017 |
Rogell BM, Fischer B, Rettel M, Krijgsveld J, Castello A, Hentze MW. Specific RNP capture with antisense LNA/DNA mixmers. Rna (New York, N.Y.). PMID 28476952 DOI: 10.1261/Rna.060798.117 |
0.419 |
|
| 2017 |
Muckenthaler MU, Rivella S, Hentze MW, Galy B. A Red Carpet for Iron Metabolism. Cell. 168: 344-361. PMID 28129536 DOI: 10.1016/J.Cell.2016.12.034 |
0.457 |
|
| 2017 |
Haberman N, Huppertz I, Attig J, König J, Wang Z, Hauer C, Hentze MW, Kulozik AE, Le Hir H, Curk T, Sibley CR, Zarnack K, Ule J. Insights into the design and interpretation of iCLIP experiments. Genome Biology. 18: 7. PMID 28093074 DOI: 10.1186/S13059-016-1130-X |
0.326 |
|
| 2017 |
Kwon E, Todorova K, Wang J, Hentze M, Mandinova A. 871 YBX1 mediated translational control of the senescence secretome in epidermal progenitors Journal of Investigative Dermatology. 137. DOI: 10.1016/J.Jid.2017.02.897 |
0.313 |
|
| 2016 |
Reichel M, Liao Y, Rettel M, Ragan C, Evers M, Alleaume AM, Horos R, Hentze MW, Preiss T, Millar AA. In planta determination of the mRNA-binding proteome of Arabidopsis etiolated seedlings. The Plant Cell. PMID 27729395 DOI: 10.1105/Tpc.16.00562 |
0.399 |
|
| 2016 |
Haddad S, Wang Y, Galy B, Korf-Klingebiel M, Hirsch V, Baru AM, Rostami F, Reboll MR, Heineke J, Flögel U, Groos S, Renner A, Toischer K, Zimmermann F, Engeli S, ... ... Hentze MW, et al. Iron-regulatory proteins secure iron availability in cardiomyocytes to prevent heart failure. European Heart Journal. PMID 27545647 DOI: 10.1093/Eurheartj/Ehw333 |
0.466 |
|
| 2016 |
Hauer C, Sieber J, Schwarzl T, Hollerer I, Curk T, Alleaume AM, Hentze MW, Kulozik AE. Exon Junction Complexes Show a Distributional Bias toward Alternatively Spliced mRNAs and against mRNAs Coding for Ribosomal Proteins. Cell Reports. PMID 27475226 DOI: 10.1016/J.Celrep.2016.06.096 |
0.447 |
|
| 2016 |
Castello A, Fischer B, Frese CK, Horos R, Alleaume AM, Foehr S, Curk T, Krijgsveld J, Hentze MW. Comprehensive Identification of RNA-Binding Domains in Human Cells. Molecular Cell. PMID 27453046 DOI: 10.1016/J.Molcel.2016.06.029 |
0.387 |
|
| 2016 |
Liao Y, Castello A, Fischer B, Leicht S, Föehr S, Frese CK, Ragan C, Kurscheid S, Pagler E, Yang H, Krijgsveld J, Hentze MW, Preiss T. The Cardiomyocyte RNA-Binding Proteome: Links to Intermediary Metabolism and Heart Disease. Cell Reports. PMID 27452465 DOI: 10.1016/J.Celrep.2016.06.084 |
0.408 |
|
| 2016 |
Hollerer I, Curk T, Haase B, Benes V, Hauer C, Neu-Yilik G, Bhuvanagiri M, Hentze MW, Kulozik AE. The differential expression of alternatively polyadenylated transcripts is a common stress-induced response mechanism that modulates mammalian mRNA expression in a quantitative and qualitative fashion. Rna (New York, N.Y.). PMID 27407180 DOI: 10.1261/Rna.055657.115 |
0.394 |
|
| 2016 |
Sysoev VO, Fischer B, Frese CK, Gupta I, Krijgsveld J, Hentze MW, Castello A, Ephrussi A. Global changes of the RNA-bound proteome during the maternal-to-zygotic transition in Drosophila. Nature Communications. 7: 12128. PMID 27378189 DOI: 10.1038/Ncomms12128 |
0.378 |
|
| 2016 |
Liepelt A, Naarmann-de Vries IS, Simons N, Eichelbaum K, Foehr S, Archer SK, Castello A, Usadel B, Krijgsveld J, Preiss T, Marx G, Hentze MW, Ostareck DH, Ostareck-Lederer A. Identification of RNA-binding proteins in macrophages by interactome capture. Molecular & Cellular Proteomics : McP. PMID 27281784 DOI: 10.1074/Mcp.M115.056564 |
0.39 |
|
| 2016 |
Sieber J, Hauer C, Bhuvanagiri M, Leicht S, Krijgsveld J, Neu-Yilik G, Hentze MW, Kulozik AE. Proteomic Analysis Reveals Branch-specific Regulation of the Unfolded Protein Response by Nonsense-mediated mRNA Decay. Molecular & Cellular Proteomics : McP. 15: 1584-97. PMID 26896796 DOI: 10.1074/Mcp.M115.054056 |
0.404 |
|
| 2016 |
Castello A, Horos R, Strein C, Fischer B, Eichelbaum K, Steinmetz LM, Krijgsveld J, Hentze MW. Comprehensive Identification of RNA-Binding Proteins by RNA Interactome Capture. Methods in Molecular Biology (Clifton, N.J.). 1358: 131-9. PMID 26463381 DOI: 10.1007/978-1-4939-3067-8_8 |
0.377 |
|
| 2016 |
Vinchi F, Simmelbauer A, Altamura S, Galy B, Hentze MW, Muckenthaler M. Iron accelerates cardiovascular disease: The importance of maintaining iron balance Atherosclerosis. 252. DOI: 10.1016/J.Atherosclerosis.2016.07.030 |
0.448 |
|
| 2015 |
Beckmann BM, Horos R, Fischer B, Castello A, Eichelbaum K, Alleaume AM, Schwarzl T, Curk T, Foehr S, Huber W, Krijgsveld J, Hentze MW. The RNA-binding proteomes from yeast to man harbour conserved enigmRBPs. Nature Communications. 6: 10127. PMID 26632259 DOI: 10.1038/Ncomms10127 |
0.37 |
|
| 2015 |
Siegert I, Schödel J, Nairz M, Schatz V, Dettmer K, Dick C, Kalucka J, Franke K, Ehrenschwender M, Schley G, Beneke A, Sutter J, Moll M, Hellerbrand C, Wielockx B, ... ... Hentze MW, et al. Ferritin-Mediated Iron Sequestration Stabilizes Hypoxia-Inducible Factor-1α upon LPS Activation in the Presence of Ample Oxygen. Cell Reports. PMID 26628374 DOI: 10.1016/J.Celrep.2015.11.005 |
0.354 |
|
| 2015 |
Castello A, Hentze MW, Preiss T. Metabolic Enzymes Enjoying New Partnerships as RNA-Binding Proteins. Trends in Endocrinology and Metabolism: Tem. 26: 746-57. PMID 26520658 DOI: 10.1016/J.Tem.2015.09.012 |
0.351 |
|
| 2015 |
Theurl M, Song D, Clark E, Sterling J, Grieco S, Altamura S, Galy B, Hentze M, Muckenthaler MU, Dunaief JL. Mice with hepcidin-resistant ferroportin accumulate iron in the retina. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 26506980 DOI: 10.1096/Fj.15-276758 |
0.377 |
|
| 2015 |
Popow J, Alleaume AM, Curk T, Schwarzl T, Sauer S, Hentze MW. FASTKD2 is an RNA-binding protein required for mitochondrial RNA processing and translation. Rna (New York, N.Y.). 21: 1873-84. PMID 26370583 DOI: 10.1261/Rna.052365.115 |
0.395 |
|
| 2015 |
Hauer C, Curk T, Anders S, Schwarzl T, Alleaume AM, Sieber J, Hollerer I, Bhuvanagiri M, Huber W, Hentze MW, Kulozik AE. Improved binding site assignment by high-resolution mapping of RNA-protein interactions using iCLIP. Nature Communications. 6: 7921. PMID 26260686 DOI: 10.1038/Ncomms8921 |
0.347 |
|
| 2015 |
Nairz M, Ferring-Appel D, Casarrubea D, Sonnweber T, Viatte L, Schroll A, Haschka D, Fang FC, Hentze MW, Weiss G, Galy B. Iron Regulatory Proteins Mediate Host Resistance to Salmonella Infection. Cell Host & Microbe. 18: 254-61. PMID 26190773 DOI: 10.1016/J.Chom.2015.06.017 |
0.475 |
|
| 2015 |
Deniaud A, Karuppasamy M, Bock T, Masiulis S, Huard K, Garzoni F, Kerschgens K, Hentze MW, Kulozik AE, Beck M, Neu-Yilik G, Schaffitzel C. A network of SMG-8, SMG-9 and SMG-1 C-terminal insertion domain regulates UPF1 substrate recruitment and phosphorylation. Nucleic Acids Research. 43: 7600-11. PMID 26130714 DOI: 10.1093/Nar/Gkv668 |
0.32 |
|
| 2015 |
Guida C, Altamura S, Klein FA, Galy B, Boutros M, Ulmer AJ, Hentze MW, Muckenthaler MU. A novel inflammatory pathway mediating rapid hepcidin-independent hypoferremia. Blood. 125: 2265-75. PMID 25662334 DOI: 10.1182/Blood-2014-08-595256 |
0.477 |
|
| 2015 |
Martelli A, Schmucker S, Reutenauer L, Mathieu JR, Peyssonnaux C, Karim Z, Puy H, Galy B, Hentze MW, Puccio H. Iron regulatory protein 1 sustains mitochondrial iron loading and function in frataxin deficiency. Cell Metabolism. 21: 311-22. PMID 25651183 DOI: 10.1016/J.Cmet.2015.01.010 |
0.465 |
|
| 2015 |
Vinchi F, Simmelbauer A, Silva MCd, Altamura S, Galy B, Hentze MW, Muckenthaler MU. High Circulating Iron Levels Are a Risk Factor for Cardiovascular Disease: Clinical Implications for Iron-Overload Conditions Blood. 126: 1040-1040. DOI: 10.1182/Blood.V126.23.1040.1040 |
0.438 |
|
| 2015 |
Vinchi F, Altamura S, Silva MCd, Galy B, Hentze MW, Muckenthaler MU. Dissecting the role of systemic versus macrophage iron levels for the pathogenesis of atherosclerosis Atherosclerosis. 241. DOI: 10.1016/J.Atherosclerosis.2015.04.053 |
0.412 |
|
| 2014 |
Bhuvanagiri M, Lewis J, Putzker K, Becker JP, Leicht S, Krijgsveld J, Batra R, Turnwald B, Jovanovic B, Hauer C, Sieber J, Hentze MW, Kulozik AE. 5-azacytidine inhibits nonsense-mediated decay in a MYC-dependent fashion. Embo Molecular Medicine. 6: 1593-609. PMID 25319547 DOI: 10.15252/Emmm.201404461 |
0.353 |
|
| 2014 |
Kramer K, Sachsenberg T, Beckmann BM, Qamar S, Boon KL, Hentze MW, Kohlbacher O, Urlaub H. Photo-cross-linking and high-resolution mass spectrometry for assignment of RNA-binding sites in RNA-binding proteins. Nature Methods. 11: 1064-70. PMID 25173706 DOI: 10.1038/Nmeth.3092 |
0.379 |
|
| 2014 |
Altamura S, Kessler R, Gröne HJ, Gretz N, Hentze MW, Galy B, Muckenthaler MU. Resistance of ferroportin to hepcidin binding causes exocrine pancreatic failure and fatal iron overload. Cell Metabolism. 20: 359-67. PMID 25100063 DOI: 10.1016/J.Cmet.2014.07.007 |
0.474 |
|
| 2014 |
Strein C, Alleaume AM, Rothbauer U, Hentze MW, Castello A. A versatile assay for RNA-binding proteins in living cells. Rna (New York, N.Y.). 20: 721-31. PMID 24664470 DOI: 10.1261/Rna.043562.113 |
0.394 |
|
| 2014 |
Chung J, Anderson SA, Gwynn B, Deck KM, Chen MJ, Langer NB, Shaw GC, Huston NC, Boyer LF, Datta S, Paradkar PN, Li L, Wei Z, Lambert AJ, Sahr K, ... ... Hentze MW, et al. Iron regulatory protein-1 protects against mitoferrin-1-deficient porphyria. The Journal of Biological Chemistry. 289: 7835-43. PMID 24509859 DOI: 10.1074/Jbc.M114.547778 |
0.538 |
|
| 2014 |
Hollerer I, Grund K, Hentze MW, Kulozik AE. mRNA 3'end processing: A tale of the tail reaches the clinic. Embo Molecular Medicine. 6: 16-26. PMID 24408965 DOI: 10.1002/Emmm.201303300 |
0.356 |
|
| 2014 |
Mleczko-Sanecka K, Roche F, da Silva AR, Call D, D'Alessio F, Ragab A, Lapinski PE, Ummanni R, Korf U, Oakes C, Damm G, D'Alessandro LA, Klingmüller U, King PD, Boutros M, ... Hentze MW, et al. Unbiased RNAi screen for hepcidin regulators links hepcidin suppression to proliferative Ras/RAF and nutrient-dependent mTOR signaling. Blood. 123: 1574-85. PMID 24385536 DOI: 10.1182/Blood-2013-07-515957 |
0.447 |
|
| 2014 |
Luscieti S, Boyl PP, Galy B, Gutierrez L, Shvartsman M, Morales MP, Hentze MW, Witke W, Sanchez M. Profilin2 is controlled by the Iron Regulatory Proteins and modulates iron homeostasis Blood. 124: 749-749. DOI: 10.1182/Blood.V124.21.749.749 |
0.546 |
|
| 2014 |
Chung J, Anderson SA, Gwynn B, Deck KM, Chen MJ, Langer NB, Shaw GC, Huston NC, Boyer LF, Datta S, Paradkar PN, Li L, Wei Z, Lambert AJ, Sahr K, ... ... Hentze MW, et al. Erratum: Iron regulatory protein-1 protects against mitoferrin-1-deficient porphyria (Journal of Biological Chemistry (2014) 289 (7835-7843)) Journal of Biological Chemistry. 289. DOI: 10.1074/Jbc.A114.547778 |
0.48 |
|
| 2014 |
Vinchi F, Altamura S, Silva MCd, Galy B, Hentze MW, Muckenthaler MU. Iron as a risk factor for atherosclerosis: Confirming the iron hypothesis in a mouse model of hemochromatosis Atherosclerosis. 235. DOI: 10.1016/J.Atherosclerosis.2014.05.018 |
0.441 |
|
| 2013 |
Kwon SC, Yi H, Eichelbaum K, Föhr S, Fischer B, You KT, Castello A, Krijgsveld J, Hentze MW, Kim VN. The RNA-binding protein repertoire of embryonic stem cells. Nature Structural & Molecular Biology. 20: 1122-30. PMID 23912277 DOI: 10.1038/Nsmb.2638 |
0.403 |
|
| 2013 |
Hentze MW, Izaurralde E. Making sense of nonsense. Nature Structural & Molecular Biology. 20: 651-3. PMID 23739166 DOI: 10.1038/Nsmb.2601 |
0.44 |
|
| 2013 |
Galy B, Ferring-Appel D, Becker C, Gretz N, Gröne HJ, Schümann K, Hentze MW. Iron regulatory proteins control a mucosal block to intestinal iron absorption. Cell Reports. 3: 844-57. PMID 23523353 DOI: 10.1016/J.Celrep.2013.02.026 |
0.489 |
|
| 2013 |
Casarrubea D, Viatte L, Hallas T, Vasanthakumar A, Eisenstein RS, Schümann K, Hentze MW, Galy B. Abnormal body iron distribution and erythropoiesis in a novel mouse model with inducible gain of iron regulatory protein (IRP)-1 function. Journal of Molecular Medicine (Berlin, Germany). 91: 871-81. PMID 23455710 DOI: 10.1007/S00109-013-1008-2 |
0.512 |
|
| 2013 |
Castello A, Fischer B, Hentze MW, Preiss T. RNA-binding proteins in Mendelian disease. Trends in Genetics : Tig. 29: 318-27. PMID 23415593 DOI: 10.1016/J.Tig.2013.01.004 |
0.396 |
|
| 2013 |
Castello A, Horos R, Strein C, Fischer B, Eichelbaum K, Steinmetz LM, Krijgsveld J, Hentze MW. System-wide identification of RNA-binding proteins by interactome capture. Nature Protocols. 8: 491-500. PMID 23411631 DOI: 10.1038/Nprot.2013.020 |
0.421 |
|
| 2013 |
Anderson SA, Nizzi CP, Chang YI, Deck KM, Schmidt PJ, Galy B, Damnernsawad A, Broman AT, Kendziorski C, Hentze MW, Fleming MD, Zhang J, Eisenstein RS. The IRP1-HIF-2α axis coordinates iron and oxygen sensing with erythropoiesis and iron absorption. Cell Metabolism. 17: 282-90. PMID 23395174 DOI: 10.1016/J.Cmet.2013.01.007 |
0.52 |
|
| 2013 |
Altamura S, Gröne HJ, Kessler R, Galy B, Hentze MW. In Vivo Disruption Of The Hepcidin−Ferroportin Regulatory Circuitry Causes Fatal Systemic and Exocrine Pancreatic Iron Overload Blood. 122: 175-175. DOI: 10.1182/Blood.V122.21.175.175 |
0.457 |
|
| 2012 |
Casanova CM, Sehr P, Putzker K, Hentze MW, Neumann B, Duncan KE, Thoma C. Automated high-throughput RNAi screening in human cells combined with reporter mRNA transfection to identify novel regulators of translation. Plos One. 7: e45943. PMID 23029333 DOI: 10.1371/Journal.Pone.0045943 |
0.364 |
|
| 2012 |
Gebauer F, Preiss T, Hentze MW. From cis-regulatory elements to complex RNPs and back. Cold Spring Harbor Perspectives in Biology. 4: a012245. PMID 22751153 DOI: 10.1101/Cshperspect.A012245 |
0.404 |
|
| 2012 |
D'Alessio F, Hentze MW, Muckenthaler MU. The hemochromatosis proteins HFE, TfR2, and HJV form a membrane-associated protein complex for hepcidin regulation. Journal of Hepatology. 57: 1052-60. PMID 22728873 DOI: 10.1016/J.Jhep.2012.06.015 |
0.394 |
|
| 2012 |
Castello A, Fischer B, Eichelbaum K, Horos R, Beckmann BM, Strein C, Davey NE, Humphreys DT, Preiss T, Steinmetz LM, Krijgsveld J, Hentze MW. Insights into RNA biology from an atlas of mammalian mRNA-binding proteins. Cell. 149: 1393-406. PMID 22658674 DOI: 10.1016/J.Cell.2012.04.031 |
0.429 |
|
| 2012 |
Moretti F, Kaiser C, Zdanowicz-Specht A, Hentze MW. PABP and the poly(A) tail augment microRNA repression by facilitated miRISC binding. Nature Structural & Molecular Biology. 19: 603-8. PMID 22635249 DOI: 10.1038/Nsmb.2309 |
0.327 |
|
| 2011 |
Sanchez M, Galy B, Schwanhaeusser B, Blake J, Bähr-Ivacevic T, Benes V, Selbach M, Muckenthaler MU, Hentze MW. Iron regulatory protein-1 and -2: transcriptome-wide definition of binding mRNAs and shaping of the cellular proteome by iron regulatory proteins. Blood. 118: e168-79. PMID 21940823 DOI: 10.1182/Blood-2011-04-343541 |
0.586 |
|
| 2011 |
Medenbach J, Seiler M, Hentze MW. Translational control via protein-regulated upstream open reading frames. Cell. 145: 902-13. PMID 21663794 DOI: 10.1016/J.Cell.2011.05.005 |
0.459 |
|
| 2011 |
Rakotondrafara AM, Hentze MW. An efficient factor-depleted mammalian in vitro translation system. Nature Protocols. 6: 563-71. PMID 21527914 DOI: 10.1038/Nprot.2011.314 |
0.368 |
|
| 2011 |
Neu-Yilik G, Amthor B, Gehring NH, Bahri S, Paidassi H, Hentze MW, Kulozik AE. Mechanism of escape from nonsense-mediated mRNA decay of human beta-globin transcripts with nonsense mutations in the first exon. Rna (New York, N.Y.). 17: 843-54. PMID 21389146 DOI: 10.1261/Rna.2401811 |
0.337 |
|
| 2011 |
Castoldi M, Vujic Spasic M, Altamura S, Elmén J, Lindow M, Kiss J, Stolte J, Sparla R, D'Alessandro LA, Klingmüller U, Fleming RE, Longerich T, Gröne HJ, Benes V, Kauppinen S, ... Hentze MW, et al. The liver-specific microRNA miR-122 controls systemic iron homeostasis in mice. The Journal of Clinical Investigation. 121: 1386-96. PMID 21364282 DOI: 10.1172/Jci44883 |
0.427 |
|
| 2011 |
Danckwardt S, Gantzert AS, Macher-Goeppinger S, Probst HC, Gentzel M, Wilm M, Gröne HJ, Schirmacher P, Hentze MW, Kulozik AE. p38 MAPK controls prothrombin expression by regulated RNA 3' end processing. Molecular Cell. 41: 298-310. PMID 21292162 DOI: 10.1016/J.Molcel.2010.12.032 |
0.401 |
|
| 2011 |
Hentze MW. Iron Regulatory Proteins in Systemic Iron Metabolism and Erythropoiesis Blood. 118. DOI: 10.1182/Blood.V118.21.Sci-22.Sci-22 |
0.475 |
|
| 2010 |
Bhuvanagiri M, Schlitter AM, Hentze MW, Kulozik AE. NMD: RNA biology meets human genetic medicine. The Biochemical Journal. 430: 365-77. PMID 20795950 DOI: 10.1042/Bj20100699 |
0.407 |
|
| 2010 |
Lopes TJ, Luganskaja T, Vuji? Spasi? M, Hentze MW, Muckenthaler MU, Schümann K, Reich JG. Systems analysis of iron metabolism: the network of iron pools and fluxes. Bmc Systems Biology. 4: 112. PMID 20704761 DOI: 10.1186/1752-0509-4-112 |
0.472 |
|
| 2010 |
Galy B, Ferring-Appel D, Sauer SW, Kaden S, Lyoumi S, Puy H, Kölker S, Gröne HJ, Hentze MW. Iron regulatory proteins secure mitochondrial iron sufficiency and function. Cell Metabolism. 12: 194-201. PMID 20674864 DOI: 10.1016/J.Cmet.2010.06.007 |
0.506 |
|
| 2010 |
Hentze MW, Muckenthaler MU, Galy B, Camaschella C. Two to tango: regulation of Mammalian iron metabolism. Cell. 142: 24-38. PMID 20603012 DOI: 10.1016/J.Cell.2010.06.028 |
0.505 |
|
| 2010 |
Hentze MW, Preiss T. The REM phase of gene regulation. Trends in Biochemical Sciences. 35: 423-6. PMID 20554447 DOI: 10.1016/J.Tibs.2010.05.009 |
0.364 |
|
| 2010 |
Cohen LA, Gutierrez L, Weiss A, Leichtmann-Bardoogo Y, Zhang DL, Crooks DR, Sougrat R, Morgenstern A, Galy B, Hentze MW, Lazaro FJ, Rouault TA, Meyron-Holtz EG. Serum ferritin is derived primarily from macrophages through a nonclassical secretory pathway. Blood. 116: 1574-84. PMID 20472835 DOI: 10.1182/Blood-2009-11-253815 |
0.377 |
|
| 2010 |
Campillos M, Cases I, Hentze MW, Sanchez M. SIREs: searching for iron-responsive elements. Nucleic Acids Research. 38: W360-7. PMID 20460462 DOI: 10.1093/Nar/Gkq371 |
0.494 |
|
| 2010 |
Pisarev AV, Skabkin MA, Pisareva VP, Skabkina OV, Rakotondrafara AM, Hentze MW, Hellen CU, Pestova TV. The role of ABCE1 in eukaryotic posttermination ribosomal recycling. Molecular Cell. 37: 196-210. PMID 20122402 DOI: 10.1016/J.Molcel.2009.12.034 |
0.368 |
|
| 2010 |
Mleczko-Sanecka K, Casanovas G, Ragab A, Breitkopf K, Müller A, Boutros M, Dooley S, Hentze MW, Muckenthaler MU. SMAD7 controls iron metabolism as a potent inhibitor of hepcidin expression. Blood. 115: 2657-65. PMID 20040761 DOI: 10.1182/Blood-2009-09-238105 |
0.466 |
|
| 2009 |
Duncan KE, Strein C, Hentze MW. The SXL-UNR corepressor complex uses a PABP-mediated mechanism to inhibit ribosome recruitment to msl-2 mRNA. Molecular Cell. 36: 571-82. PMID 19941818 DOI: 10.1016/J.Molcel.2009.09.042 |
0.446 |
|
| 2009 |
Zdanowicz A, Thermann R, Kowalska J, Jemielity J, Duncan K, Preiss T, Darzynkiewicz E, Hentze MW. Drosophila miR2 primarily targets the m7GpppN cap structure for translational repression. Molecular Cell. 35: 881-8. PMID 19782035 DOI: 10.1016/J.Molcel.2009.09.009 |
0.324 |
|
| 2009 |
Beilharz TH, Humphreys DT, Clancy JL, Thermann R, Martin DI, Hentze MW, Preiss T. microRNA-mediated messenger RNA deadenylation contributes to translational repression in mammalian cells. Plos One. 4: e6783. PMID 19710908 DOI: 10.1371/Journal.Pone.0006783 |
0.388 |
|
| 2009 |
Clerici M, Mourão A, Gutsche I, Gehring NH, Hentze MW, Kulozik A, Kadlec J, Sattler M, Cusack S. Unusual bipartite mode of interaction between the nonsense-mediated decay factors, UPF1 and UPF2. The Embo Journal. 28: 2293-306. PMID 19556969 DOI: 10.1038/Emboj.2009.175 |
0.322 |
|
| 2009 |
Viatte L, Gröne HJ, Hentze MW, Galy B. In vivo role(s) of the iron regulatory proteins (IRP) 1 and 2 in aseptic local inflammation. Journal of Molecular Medicine (Berlin, Germany). 87: 913-21. PMID 19533074 DOI: 10.1007/S00109-009-0494-8 |
0.507 |
|
| 2009 |
Gehring NH, Lamprinaki S, Hentze MW, Kulozik AE. The hierarchy of exon-junction complex assembly by the spliceosome explains key features of mammalian nonsense-mediated mRNA decay. Plos Biology. 7: e1000120. PMID 19478851 DOI: 10.1371/Journal.Pbio.1000120 |
0.423 |
|
| 2009 |
Gehring NH, Lamprinaki S, Kulozik AE, Hentze MW. Disassembly of exon junction complexes by PYM. Cell. 137: 536-48. PMID 19410547 DOI: 10.1016/J.Cell.2009.02.042 |
0.45 |
|
| 2009 |
Casanovas G, Mleczko-Sanecka K, Altamura S, Hentze MW, Muckenthaler MU. Bone morphogenetic protein (BMP)-responsive elements located in the proximal and distal hepcidin promoter are critical for its response to HJV/BMP/SMAD. Journal of Molecular Medicine (Berlin, Germany). 87: 471-80. PMID 19229506 DOI: 10.1007/S00109-009-0447-2 |
0.426 |
|
| 2009 |
Ferring-Appel D, Hentze MW, Galy B. Cell-autonomous and systemic context-dependent functions of iron regulatory protein 2 in mammalian iron metabolism. Blood. 113: 679-87. PMID 18922858 DOI: 10.1182/Blood-2008-05-155093 |
0.465 |
|
| 2008 |
Gehring NH, Hentze MW, Kulozik AE. Tethering assays to investigate nonsense-mediated mRNA decay activating proteins. Methods in Enzymology. 448: 467-82. PMID 19111190 DOI: 10.1016/S0076-6879(08)02623-2 |
0.447 |
|
| 2008 |
Thoma C, Fraterman S, Gentzel M, Wilm M, Hentze MW. Translation initiation by the c-myc mRNA internal ribosome entry sequence and the poly(A) tail. Rna (New York, N.Y.). 14: 1579-89. PMID 18556416 DOI: 10.1261/Rna.1043908 |
0.408 |
|
| 2008 |
Muckenthaler MU, Galy B, Hentze MW. Systemic iron homeostasis and the iron-responsive element/iron-regulatory protein (IRE/IRP) regulatory network. Annual Review of Nutrition. 28: 197-213. PMID 18489257 DOI: 10.1146/Annurev.Nutr.28.061807.155521 |
0.486 |
|
| 2008 |
Verga Falzacappa MV, Casanovas G, Hentze MW, Muckenthaler MU. A bone morphogenetic protein (BMP)-responsive element in the hepcidin promoter controls HFE2-mediated hepatic hepcidin expression and its response to IL-6 in cultured cells. Journal of Molecular Medicine (Berlin, Germany). 86: 531-40. PMID 18421430 DOI: 10.1007/S00109-008-0313-7 |
0.479 |
|
| 2008 |
Danckwardt S, Hentze MW, Kulozik AE. 3' end mRNA processing: molecular mechanisms and implications for health and disease. The Embo Journal. 27: 482-98. PMID 18256699 DOI: 10.1038/Sj.Emboj.7601932 |
0.379 |
|
| 2008 |
Ivanov PV, Gehring NH, Kunz JB, Hentze MW, Kulozik AE. Interactions between UPF1, eRFs, PABP and the exon junction complex suggest an integrated model for mammalian NMD pathways. The Embo Journal. 27: 736-47. PMID 18256688 DOI: 10.1038/Emboj.2008.17 |
0.422 |
|
| 2008 |
Vujić Spasić M, Kiss J, Herrmann T, Galy B, Martinache S, Stolte J, Gröne HJ, Stremmel W, Hentze MW, Muckenthaler MU. Hfe acts in hepatocytes to prevent hemochromatosis. Cell Metabolism. 7: 173-8. PMID 18249176 DOI: 10.1182/Blood.V110.11.703.703 |
0.46 |
|
| 2008 |
Galy B, Ferring-Appel D, Kaden S, Gröne HJ, Hentze MW. Iron regulatory proteins are essential for intestinal function and control key iron absorption molecules in the duodenum. Cell Metabolism. 7: 79-85. PMID 18177727 DOI: 10.1016/J.Cmet.2007.10.006 |
0.505 |
|
| 2008 |
Schranzhofer M, Schifrer M, Galy B, Hentze MW, Mullner EW, Ponka P. A Closer Look at Cellular Iron Metabolism in IRP2 Deficient Erythroblasts. Blood. 112: 3843-3843. DOI: 10.1182/Blood.V112.11.3843.3843 |
0.509 |
|
| 2007 |
Gebauer F, Hentze MW. Studying translational control in Drosophila cell-free systems. Methods in Enzymology. 429: 23-33. PMID 17913617 DOI: 10.1016/S0076-6879(07)29002-0 |
0.341 |
|
| 2007 |
Till S, Lejeune E, Thermann R, Bortfeld M, Hothorn M, Enderle D, Heinrich C, Hentze MW, Ladurner AG. A conserved motif in Argonaute-interacting proteins mediates functional interactions through the Argonaute PIWI domain. Nature Structural & Molecular Biology. 14: 897-903. PMID 17891150 DOI: 10.1038/Nsmb1302 |
0.396 |
|
| 2007 |
Percy MJ, Sanchez M, Swierczek S, McMullin MF, Mojica-Henshaw MP, Muckenthaler MU, Prchal JT, Hentze MW. Is congenital secondary erythrocytosis/polycythemia caused by activating mutations within the HIF-2 alpha iron-responsive element? Blood. 110: 2776-7. PMID 17881647 DOI: 10.1182/Blood-2007-03-082503 |
0.328 |
|
| 2007 |
Sanchez M, Galy B, Hentze MW, Muckenthaler MU. Identification of target mRNAs of regulatory RNA-binding proteins using mRNP immunopurification and microarrays. Nature Protocols. 2: 2033-42. PMID 17703216 DOI: 10.1038/Nprot.2007.293 |
0.439 |
|
| 2007 |
Viegas MH, Gehring NH, Breit S, Hentze MW, Kulozik AE. The abundance of RNPS1, a protein component of the exon junction complex, can determine the variability in efficiency of the Nonsense Mediated Decay pathway. Nucleic Acids Research. 35: 4542-51. PMID 17586820 DOI: 10.1093/Nar/Gkm461 |
0.409 |
|
| 2007 |
Danckwardt S, Kaufmann I, Gentzel M, Foerstner KU, Gantzert AS, Gehring NH, Neu-Yilik G, Bork P, Keller W, Wilm M, Hentze MW, Kulozik AE. Splicing factors stimulate polyadenylation via USEs at non-canonical 3' end formation signals. The Embo Journal. 26: 2658-69. PMID 17464285 DOI: 10.1038/Sj.Emboj.7601699 |
0.349 |
|
| 2007 |
Mihailovich M, Thermann R, Grohovaz F, Hentze MW, Zacchetti D. Complex translational regulation of BACE1 involves upstream AUGs and stimulatory elements within the 5' untranslated region. Nucleic Acids Research. 35: 2975-85. PMID 17439957 DOI: 10.1093/Nar/Gkm191 |
0.412 |
|
| 2007 |
Sanchez M, Galy B, Muckenthaler MU, Hentze MW. Iron-regulatory proteins limit hypoxia-inducible factor-2alpha expression in iron deficiency. Nature Structural & Molecular Biology. 14: 420-6. PMID 17417656 DOI: 10.1038/Nsmb1222 |
0.558 |
|
| 2007 |
Fillebeen C, Muckenthaler M, Andriopoulos B, Bisaillon M, Mounir Z, Hentze MW, Koromilas AE, Pantopoulos K. Expression of the subgenomic hepatitis C virus replicon alters iron homeostasis in Huh7 cells. Journal of Hepatology. 47: 12-22. PMID 17399844 DOI: 10.1016/J.Jhep.2007.01.035 |
0.623 |
|
| 2007 |
Ludwiczek S, Theurl I, Muckenthaler MU, Jakab M, Mair SM, Theurl M, Kiss J, Paulmichl M, Hentze MW, Ritter M, Weiss G. Ca2+ channel blockers reverse iron overload by a new mechanism via divalent metal transporter-1. Nature Medicine. 13: 448-54. PMID 17293870 DOI: 10.1038/Nm1542 |
0.457 |
|
| 2007 |
Vujic Spasic M, Kiss J, Herrmann T, Kessler R, Stolte J, Galy B, Rathkolb B, Wolf E, Stremmel W, Hentze MW, Muckenthaler MU. Physiologic systemic iron metabolism in mice deficient for duodenal Hfe. Blood. 109: 4511-7. PMID 17264297 DOI: 10.1182/Blood-2006-07-036186 |
0.497 |
|
| 2007 |
Verga Falzacappa MV, Vujic Spasic M, Kessler R, Stolte J, Hentze MW, Muckenthaler MU. STAT3 mediates hepatic hepcidin expression and its inflammatory stimulation. Blood. 109: 353-8. PMID 16946298 DOI: 10.1182/Blood-2006-07-033969 |
0.485 |
|
| 2007 |
Schranzhofer M, Schifrer M, Galy B, Hentze M, Ponka P, Ernst MW. Low Cytosolic Non-Heme Iron Levels in Erythroid Cells Prevent IRP2-Mediated Ferritin Upregulation during Differentiation. Blood. 110: 705-705. DOI: 10.1182/Blood.V110.11.705.705 |
0.515 |
|
| 2007 |
Hentze MW, Gebauer F, Preiss T. Cis-regulatory sequences and trans-acting factors in translation control Cold Spring Harbor Monograph Archive. 48: 269-295. DOI: 10.1101/087969767.48.269 |
0.424 |
|
| 2006 |
Galy B, Hölter SM, Klopstock T, Ferring D, Becker L, Kaden S, Wurst W, Gröne HJ, Hentze MW. Iron homeostasis in the brain: complete iron regulatory protein 2 deficiency without symptomatic neurodegeneration in the mouse. Nature Genetics. 38: 967-9; discussion 96. PMID 16940998 DOI: 10.1038/Ng0906-967 |
0.475 |
|
| 2006 |
Boelz S, Neu-Yilik G, Gehring NH, Hentze MW, Kulozik AE. A chemiluminescence-based reporter system to monitor nonsense-mediated mRNA decay. Biochemical and Biophysical Research Communications. 349: 186-91. PMID 16934750 DOI: 10.1016/J.Bbrc.2006.08.017 |
0.428 |
|
| 2006 |
Holbrook JA, Neu-Yilik G, Gehring NH, Kulozik AE, Hentze MW. Internal ribosome entry sequence-mediated translation initiation triggers nonsense-mediated decay. Embo Reports. 7: 722-6. PMID 16799467 DOI: 10.1038/Sj.Embor.7400721 |
0.441 |
|
| 2006 |
Corna G, Galy B, Hentze MW, Cairo G. IRP1-independent alterations of cardiac iron metabolism in doxorubicin-treated mice. Journal of Molecular Medicine (Berlin, Germany). 84: 551-60. PMID 16770644 DOI: 10.1007/S00109-006-0068-Y |
0.48 |
|
| 2006 |
Sanchez M, Galy B, Dandekar T, Bengert P, Vainshtein Y, Stolte J, Muckenthaler MU, Hentze MW. Iron regulation and the cell cycle: identification of an iron-responsive element in the 3'-untranslated region of human cell division cycle 14A mRNA by a refined microarray-based screening strategy. The Journal of Biological Chemistry. 281: 22865-74. PMID 16760464 DOI: 10.1074/Jbc.M603876200 |
0.551 |
|
| 2006 |
Stockklausner C, Breit S, Neu-Yilik G, Echner N, Hentze MW, Kulozik AE, Gehring NH. The uORF-containing thrombopoietin mRNA escapes nonsense-mediated decay (NMD). Nucleic Acids Research. 34: 2355-63. PMID 16679454 DOI: 10.1093/Nar/Gkl277 |
0.432 |
|
| 2006 |
Kunz JB, Neu-Yilik G, Hentze MW, Kulozik AE, Gehring NH. Functions of hUpf3a and hUpf3b in nonsense-mediated mRNA decay and translation. Rna (New York, N.Y.). 12: 1015-22. PMID 16601204 DOI: 10.1261/Rna.12506 |
0.411 |
|
| 2006 |
Danckwardt S, Hartmann K, Gehring NH, Hentze MW, Kulozik AE. 3' end processing of the prothrombin mRNA in thrombophilia. Acta Haematologica. 115: 192-7. PMID 16549895 DOI: 10.1159/000090934 |
0.302 |
|
| 2006 |
Chekulaeva M, Hentze MW, Ephrussi A. Bruno acts as a dual repressor of oskar translation, promoting mRNA oligomerization and formation of silencing particles. Cell. 124: 521-33. PMID 16469699 DOI: 10.1016/J.Cell.2006.01.031 |
0.423 |
|
| 2006 |
Duncan K, Grskovic M, Strein C, Beckmann K, Niggeweg R, Abaza I, Gebauer F, Wilm M, Hentze MW. Sex-lethal imparts a sex-specific function to UNR by recruiting it to the msl-2 mRNA 3' UTR: translational repression for dosage compensation. Genes & Development. 20: 368-79. PMID 16452508 DOI: 10.1101/Gad.371406 |
0.342 |
|
| 2006 |
Mok H, Mlodnicka AE, Hentze MW, Muckenthaler M, Schumacher A. The molecular circuitry regulating the switch between iron deficiency and overload in mice. The Journal of Biological Chemistry. 281: 7946-51. PMID 16418170 DOI: 10.1074/Jbc.M509857200 |
0.497 |
|
| 2006 |
Paw BH, Gwynn B, Langer NB, Shaw GC, Lambert AJ, Boyer LA, Li L, Stolte J, Robledo RF, Sahr KE, Schlaeger TM, Hentze MW, Muckenthaler MU, Kaplan J, Peters LL. Targeted Disruption of the Mouse Mitoferrin (Slc25A37) Mitochondrial Solute Carrier Results in Defective Primitive and Definitive Erythropoiesis. Blood. 108: 265-265. DOI: 10.1182/Blood.V108.11.265.265 |
0.381 |
|
| 2006 |
Danckwardt S, Gentzel M, Gehring NH, Kaufmann I, Neu-Yilik G, Wilm M, Hentze MW, Kulozik AE. The Physiology of Prothrombin Gene Expression Integrates RNA Polyadenylation and Splicing in a Novel Regulatable 3′ RNP-Complex. Blood. 108: 1601-1601. DOI: 10.1182/Blood.V108.11.1601.1601 |
0.38 |
|
| 2005 |
Galy B, Ferring D, Hentze MW. Generation of conditional alleles of the murine Iron Regulatory Protein (IRP)-1 and -2 genes. Genesis (New York, N.Y. : 2000). 43: 181-8. PMID 16283625 DOI: 10.1002/Gene.20169 |
0.389 |
|
| 2005 |
Gehring NH, Kunz JB, Neu-Yilik G, Breit S, Viegas MH, Hentze MW, Kulozik AE. Exon-junction complex components specify distinct routes of nonsense-mediated mRNA decay with differential cofactor requirements. Molecular Cell. 20: 65-75. PMID 16209946 DOI: 10.1016/J.Molcel.2005.08.012 |
0.431 |
|
| 2005 |
Hundsdoerfer P, Thoma C, Hentze MW. Eukaryotic translation initiation factor 4GI and p97 promote cellular internal ribosome entry sequence-driven translation. Proceedings of the National Academy of Sciences of the United States of America. 102: 13421-6. PMID 16174738 DOI: 10.1073/Pnas.0506536102 |
0.399 |
|
| 2005 |
Beckmann K, Grskovic M, Gebauer F, Hentze MW. A Dual Inhibitory Mechanism Restricts msl-2 mRNA Translation for Dosage Compensation in Drosophila Cell. 122: 529-540. PMID 16122421 DOI: 10.1016/J.Cell.2005.06.011 |
0.434 |
|
| 2005 |
Galy B, Ferring D, Minana B, Bell O, Janser HG, Muckenthaler M, Schümann K, Hentze MW. Altered body iron distribution and microcytosis in mice deficient in iron regulatory protein 2 (IRP2). Blood. 106: 2580-9. PMID 15956281 DOI: 10.1182/Blood-2005-04-1365 |
0.495 |
|
| 2005 |
Fillebeen C, Rivas-Estilla AM, Bisaillon M, Ponka P, Muckenthaler M, Hentze MW, Koromilas AE, Pantopoulos K. Iron inactivates the RNA polymerase NS5B and suppresses subgenomic replication of hepatitis C Virus. The Journal of Biological Chemistry. 280: 9049-57. PMID 15637067 DOI: 10.1074/Jbc.M412687200 |
0.657 |
|
| 2005 |
Schumacher A, Mok H, Mlodnicka AE, Hentze MW, Muckenthaler M. The Molecular Signature of Iron Metabolism in Polycythaemia Mice. Blood. 106: 3579-3579. DOI: 10.1182/Blood.V106.11.3579.3579 |
0.493 |
|
| 2004 |
Gebauer F, Hentze MW. Molecular mechanisms of translational control Nature Reviews Molecular Cell Biology. 5: 827-835. PMID 15459663 DOI: 10.1038/Nrm1488 |
0.352 |
|
| 2004 |
Thoma C, Bergamini G, Galy B, Hundsdoerfer P, Hentze MW. Enhancement of IRES-mediated translation of the c-myc and BiP mRNAs by the poly(A) tail is independent of intact eIF4G and PABP. Molecular Cell. 15: 925-35. PMID 15383282 DOI: 10.1016/J.Molcel.2004.08.021 |
0.431 |
|
| 2004 |
Muckenthaler MU, Rodrigues P, Macedo MG, Minana B, Brennan K, Cardoso EM, Hentze MW, de Sousa M. Molecular analysis of iron overload in beta2-microglobulin-deficient mice. Blood Cells, Molecules & Diseases. 33: 125-31. PMID 15315790 DOI: 10.1016/J.Bcmd.2004.05.003 |
0.48 |
|
| 2004 |
Holbrook JA, Neu-Yilik G, Hentze MW, Kulozik AE. Nonsense-mediated decay approaches the clinic Nature Genetics. 36: 801-808. PMID 15284851 DOI: 10.1038/Ng1403 |
0.373 |
|
| 2004 |
Galy B, Ferring D, Benesova M, Benes V, Hentze MW. Targeted mutagenesis of the murine IRP1 and IRP2 genes reveals context-dependent RNA processing differences in vivo. Rna (New York, N.Y.). 10: 1019-25. PMID 15208438 DOI: 10.1261/Rna.7220704 |
0.386 |
|
| 2004 |
Hentze MW, Muckenthaler MU, Andrews NC. Balancing acts: molecular control of mammalian iron metabolism. Cell. 117: 285-97. PMID 15109490 DOI: 10.1016/S0092-8674(04)00343-5 |
0.486 |
|
| 2004 |
Roy CN, Custodio AO, de Graaf J, Schneider S, Akpan I, Montross LK, Sanchez M, Gaudino A, Hentze MW, Andrews NC, Muckenthaler MU. An Hfe-dependent pathway mediates hyposideremia in response to lipopolysaccharide-induced inflammation in mice. Nature Genetics. 36: 481-5. PMID 15098034 DOI: 10.1038/Ng1350 |
0.47 |
|
| 2004 |
Schümann K, Brennan K, Weiss M, Pantopoulos K, Hentze MW. Rat duodenal IRP1 activity and iron absorption in iron deficiency and after HO perfusion. European Journal of Clinical Investigation. 34: 275-82. PMID 15086359 DOI: 10.1111/J.1365-2362.2004.01335.X |
0.651 |
|
| 2004 |
Neu-Yilik G, Gehring NH, Hentze MW, Kulozik AE. Nonsense-mediated mRNA decay: from vacuum cleaner to Swiss army knife Genome Biology. 5: 218-218. PMID 15059251 DOI: 10.1186/Gb-2004-5-4-218 |
0.417 |
|
| 2004 |
Bonnah RA, Muckenthaler MU, Carlson H, Minana B, Enns CA, Hentze MW, So M. Expression of epithelial cell iron-related genes upon infection by Neisseria meningitidis. Cellular Microbiology. 6: 473-84. PMID 15056217 DOI: 10.1111/J.1462-5822.2004.00376.X |
0.494 |
|
| 2004 |
Thoma C, Ostareck-Lederer A, Hentze MW. A poly(A) tail-responsive in vitro system for cap- or IRES-driven translation from HeLa cells. Methods of Molecular Biology. 257: 171-180. PMID 14770005 DOI: 10.1385/1-59259-750-5:171 |
0.352 |
|
| 2004 |
Baron-Benhamou J, Gehring NH, Kulozik AE, Hentze MW. Using the λN Peptide to Tether Proteins to RNAs Methods of Molecular Biology. 257: 135-153. PMID 14770003 DOI: 10.1385/1-59259-750-5:135 |
0.431 |
|
| 2004 |
Wang J, Chen G, Muckenthaler M, Galy B, Hentze MW, Pantopoulos K. Iron-mediated degradation of IRP2, an unexpected pathway involving a 2-oxoglutarate-dependent oxygenase activity. Molecular and Cellular Biology. 24: 954-65. PMID 14729944 DOI: 10.1128/Mcb.24.3.954-965.2004 |
0.683 |
|
| 2004 |
Herrmann T, Muckenthaler M, van der Hoeven F, Brennan K, Gehrke SG, Hubert N, Sergi C, Gröne HJ, Kaiser I, Gosch I, Volkmann M, Riedel HD, Hentze MW, Stewart AF, Stremmel W. Iron overload in adult Hfe-deficient mice independent of changes in the steady-state expression of the duodenal iron transporters DMT1 and Ireg1/ferroportin. Journal of Molecular Medicine (Berlin, Germany). 82: 39-48. PMID 14618243 DOI: 10.1007/S00109-003-0508-X |
0.513 |
|
| 2003 |
Ohnishi T, Yamashita A, Kashima I, Schell T, Anders KR, Grimson A, Hachiya T, Hentze MW, Anderson P, Ohno S. Phosphorylation of hUPF1 induces formation of mRNA surveillance complexes containing hSMG-5 and hSMG-7. Molecular Cell. 12: 1187-200. PMID 14636577 DOI: 10.1016/S1097-2765(03)00443-X |
0.376 |
|
| 2003 |
Preiss T, Hentze MW. Starting the protein synthesis machine: eukaryotic translation initiation. Bioessays. 25: 1201-1211. PMID 14635255 DOI: 10.1002/Bies.10362 |
0.409 |
|
| 2003 |
Preiss T, Baron-Benhamou J, Ansorge W, Hentze MW. Homodirectional changes in transcriptome composition and mRNA translation induced by rapamycin and heat shock. Nature Structural & Molecular Biology. 10: 1039-1047. PMID 14608375 DOI: 10.1038/Nsb1015 |
0.404 |
|
| 2003 |
Grskovic M, Hentze MW, Gebauer F. A co-repressor assembly nucleated by Sex-lethal in the 3'UTR mediates translational control of Drosophila msl-2 mRNA The Embo Journal. 22: 5571-5581. PMID 14532129 DOI: 10.1093/Emboj/Cdg539 |
0.45 |
|
| 2003 |
Gebauer F, Grskovic M, Hentze MW. Drosophila sex-lethal inhibits the stable association of the 40S ribosomal subunit with msl-2 mRNA. Molecular Cell. 11: 1397-1404. PMID 12769862 DOI: 10.1016/S1097-2765(03)00176-X |
0.422 |
|
| 2003 |
Baron-Benhamou J, Fortes P, Inada T, Preiss T, Hentze MW. The interaction of the cap-binding complex (CBC) with eIF4G is dispensable for translation in yeast. Rna. 9: 654-662. PMID 12756324 DOI: 10.1261/Rna.5100903 |
0.439 |
|
| 2003 |
Schell T, Köcher T, Wilm M, Seraphin B, Kulozik AE, Hentze MW. Complexes between the nonsense-mediated mRNA decay pathway factor human upf1 (up-frameshift protein 1) and essential nonsense-mediated mRNA decay factors in HeLa cells. Biochemical Journal. 373: 775-783. PMID 12723973 DOI: 10.1042/Bj20021920 |
0.403 |
|
| 2003 |
Gehring NH, Neu-Yilik G, Schell T, Hentze MW, Kulozik AE. Y14 and hUpf3b form an NMD-activating complex. Molecular Cell. 11: 939-949. PMID 12718880 DOI: 10.1016/S1097-2765(03)00142-4 |
0.413 |
|
| 2003 |
Muckenthaler M, Roy CN, Custodio AO, Miñana B, deGraaf J, Montross LK, Andrews NC, Hentze MW. Regulatory defects in liver and intestine implicate abnormal hepcidin and Cybrd1 expression in mouse hemochromatosis. Nature Genetics. 34: 102-7. PMID 12704390 DOI: 10.1038/Ng1152 |
0.447 |
|
| 2003 |
Thompson K, Menzies S, Muckenthaler M, Torti FM, Wood T, Torti SV, Hentze MW, Beard J, Connor J. Mouse brains deficient in H-ferritin have normal iron concentration but a protein profile of iron deficiency and increased evidence of oxidative stress. Journal of Neuroscience Research. 71: 46-63. PMID 12478613 DOI: 10.1002/Jnr.10463 |
0.42 |
|
| 2003 |
Muckenthaler M, Richter A, Gunkel N, Riedel D, Polycarpou-Schwarz M, Hentze S, Falkenhahn M, Stremmel W, Ansorge W, Hentze MW. Relationships and distinctions in iron-regulatory networks responding to interrelated signals. Blood. 101: 3690-3698. PMID 12393473 DOI: 10.1182/Blood-2002-07-2140 |
0.487 |
|
| 2002 |
Hubert N, Hentze MW. Previously uncharacterized isoforms of divalent metal transporter (DMT)-1: implications for regulation and cellular function. Proceedings of the National Academy of Sciences of the United States of America. 99: 12345-50. PMID 12209011 DOI: 10.1073/Pnas.192423399 |
0.546 |
|
| 2002 |
SCHüMANN K, Borch-Iohnsen B, Hentze MW, Marx JJM. Tolerable upper intakes for dietary iron set by the US Food and Nutrition Board. The American Journal of Clinical Nutrition. 76: 499-500. PMID 12197990 DOI: 10.1093/Ajcn/76.3.499 |
0.319 |
|
| 2002 |
Ostareck-Lederer A, Ostareck DH, Cans C, Neubauer G, Bomsztyk K, Superti-Furga G, Hentze MW. c-Src-Mediated Phosphorylation of hnRNP K Drives Translational Activation of Specifically Silenced mRNAs Molecular and Cellular Biology. 22: 4535-4543. PMID 12052863 DOI: 10.1128/Mcb.22.13.4535-4543.2002 |
0.41 |
|
| 2002 |
Schell T, Kulozik AE, Hentze MW. Integration of splicing, transport and translation to achieve mRNA quality control by the nonsense-mediated decay pathway Genome Biology. 3: 1-6. PMID 11897029 DOI: 10.1186/Gb-2002-3-3-Reviews1006 |
0.425 |
|
| 2002 |
Danckwardt S, Neu-Yilik G, Thermann R, Frede U, Hentze MW, Kulozik AE. Abnormally spliced β-globin mRNAs: a single point mutation generates transcripts sensitive and insensitive to nonsense-mediated mRNA decay Blood. 99: 1811-1816. PMID 11861299 DOI: 10.1182/Blood.V99.5.1811 |
0.44 |
|
| 2002 |
Brocke KS, Neu-Yilik G, Gehring NH, Hentze MW, Kulozik AE. The human intronless melanocortin 4-receptor gene is NMD insensitive Human Molecular Genetics. 11: 331-335. PMID 11823452 DOI: 10.1093/Hmg/11.3.331 |
0.378 |
|
| 2001 |
Gebauer F, Ostareck DH, Ostareck-Lederer A, Grskovic M, Hentze MW. Translational control of 15-lipoxygenase and msl-2 mRNAs: single regulators or corepressor assemblies? Cold Spring Harbor Symposia On Quantitative Biology. 66: 329-336. PMID 12762035 DOI: 10.1101/Sqb.2001.66.329 |
0.386 |
|
| 2001 |
Gunshin H, Allerson CR, Polycarpou-Schwarz M, Rofts A, Rogers JT, Kishi F, Hentze MW, Rouault TA, Andrews NC, Hediger MA. Iron-dependent regulation of the divalent metal ion transporter. Febs Letters. 509: 309-16. PMID 11741608 DOI: 10.1016/S0014-5793(01)03189-1 |
0.537 |
|
| 2001 |
Thoma C, Hasselblatt P, Köck J, Chang SF, Hockenjos B, Will H, Hentze MW, Blum HE, von Weizsäcker F, Offensperger WB. Generation of stable mRNA fragments and translation of N-truncated proteins induced by antisense oligodeoxynucleotides. Molecular Cell. 8: 865-72. PMID 11684021 DOI: 10.1016/S1097-2765(01)00364-1 |
0.45 |
|
| 2001 |
Hentze MW. Believe It or Not--Translation in the Nucleus Science. 293: 1058-1059. PMID 11498567 DOI: 10.1126/Science.1063290 |
0.381 |
|
| 2001 |
Gehring NH, Frede U, Neu-Yilik G, Hundsdoerfer P, Vetter B, Hentze MW, Kulozik AE. Increased efficiency of mRNA 3' end formation: a new genetic mechanism contributing to hereditary thrombophilia. Nature Genetics. 28: 389-392. PMID 11443298 DOI: 10.1038/Ng578 |
0.373 |
|
| 2001 |
Pöyry TAA, Hentze MW, Jackson RJ. Construction of regulatable picornavirus IRESes as a test of current models of the mechanism of internal translation initiation. Rna. 7: 647-660. PMID 11350029 DOI: 10.1017/S1355838201001911 |
0.438 |
|
| 2001 |
Mueller S, Pantopoulos K, Hübner CA, Stremmel W, Hentze MW. IRP1 activation by extracellular oxidative stress in the perfused rat liver. The Journal of Biological Chemistry. 276: 23192-6. PMID 11297549 DOI: 10.1074/Jbc.M100654200 |
0.654 |
|
| 2001 |
Habelhah H, Shah K, Huang L, Ostareck-Lederer A, Burlingame AL, Shokat KM, Hentze MW, Ronai Z. ERK phosphorylation drives cytoplasmic accumulation of hnRNP-K and inhibition of mRNA translation. Nature Cell Biology. 3: 325-30. PMID 11231586 DOI: 10.1038/35060131 |
0.344 |
|
| 2001 |
Gregorio ED, Baron J, Preiss T, Hentze MW. Tethered-function analysis reveals that eIF4E can recruit ribosomes independent of its binding to the cap structure Rna. 7: 106-113. PMID 11214172 DOI: 10.1017/S1355838201000577 |
0.389 |
|
| 2001 |
Ostareck DH, Ostareck-Lederer A, Shatsky IN, Hentze MW. Lipoxygenase mRNA silencing in erythroid differentiation: The 3'UTR regulatory complex controls 60S ribosomal subunit joining. Cell. 104: 281-290. PMID 11207368 DOI: 10.1016/S0092-8674(01)00212-4 |
0.406 |
|
| 2001 |
Neu‐Yilik G, Gehring NH, Thermann R, Frede U, Hentze MW, Kulozik AE. Splicing and 3′ end formation in the definition of nonsense‐mediated decay‐competent human β‐globin mRNPs The Embo Journal. 20: 532-540. PMID 11157759 DOI: 10.1093/Emboj/20.3.532 |
0.363 |
|
| 2000 |
Hentze MW, Izaurralde E, Séraphin B. A new era for the RNA world - Conference: RNA 2000 Embo Reports. 1: 394-398. PMID 11258477 DOI: 10.1093/Embo-Reports/Kvd100 |
0.346 |
|
| 2000 |
Bergamini G, Preiss T, Hentze MW. Picornavirus IRESes and the poly(A) tail jointly promote cap-independent translation in a mammalian cell-free system. Rna. 6: 1781-1790. PMID 11142378 DOI: 10.1017/S1355838200001679 |
0.414 |
|
| 2000 |
Paraskeva E, Hentze MW. [25] Translational repression assay procedure: A method to study RNA-protein interactions in yeast Methods in Enzymology. 318: 374-384. PMID 10890000 DOI: 10.1016/S0076-6879(00)18064-4 |
0.347 |
|
| 2000 |
McKie AT, Marciani P, Rolfs A, Brennan K, Wehr K, Barrow D, Miret S, Bomford A, Peters TJ, Farzaneh F, Hediger MA, Hentze MW, Simpson RJ. A novel duodenal iron-regulated transporter, IREG1, implicated in the basolateral transfer of iron to the circulation. Molecular Cell. 5: 299-309. PMID 10882071 DOI: 10.1016/S1097-2765(00)80425-6 |
0.514 |
|
| 2000 |
Fortes P, Inada T, Preiss T, Hentze MW, Mattaj IW, Sachs AB. The Yeast Nuclear Cap Binding Complex Can Interact with Translation Factor eIF4G and Mediate Translation Initiation Molecular Cell. 6: 191-196. DOI: 10.1016/S1097-2765(05)00003-1 |
0.437 |
|
| 1999 |
Gebauer F, Corona DFV, Preiss T, Becker PB, Hentze MW. Translational control of dosage compensation in Drosophila by Sex-lethal: cooperative silencing via the 5' and 3' UTRs of msl-2 mRNA is independent of the poly(A) tail. The Embo Journal. 18: 6146-6154. PMID 10545124 DOI: 10.1093/Emboj/18.21.6146 |
0.442 |
|
| 1999 |
Preiss T, Hentze MW. From factors to mechanisms: translation and translational control in eukaryotes. Current Opinion in Genetics & Development. 9: 515-521. PMID 10508691 DOI: 10.1016/S0959-437X(99)00005-2 |
0.385 |
|
| 1999 |
Gregorio ED, Preiss T, Hentze MW. Translation driven by an eIF4G core domain in vivo. The Embo Journal. 18: 4865-4874. PMID 10469664 DOI: 10.1093/Emboj/18.17.4865 |
0.429 |
|
| 1999 |
Brazzolotto X, Gaillard J, Pantopoulos K, Hentze MW, Moulis JM. Human cytoplasmic aconitase (Iron regulatory protein 1) is converted into its [3Fe-4S] form by hydrogen peroxide in vitro but is not activated for iron-responsive element binding. The Journal of Biological Chemistry. 274: 21625-30. PMID 10419470 DOI: 10.1074/Jbc.274.31.21625 |
0.695 |
|
| 1999 |
Gegout V, Schlegl J, Schläger B, Hentze MW, Reinbolt J, Ehresmann B, Ehresmann C, Romby P. Ligand-induced structural alterations in human iron regulatory protein-1 revealed by protein footprinting. Journal of Biological Chemistry. 274: 15052-15058. PMID 10329709 DOI: 10.1074/Jbc.274.21.15052 |
0.541 |
|
| 1999 |
Gehring NH, Hentze MW, Pantopoulos K. Inactivation of both RNA binding and aconitase activities of iron regulatory protein-1 by quinone-induced oxidative stress. The Journal of Biological Chemistry. 274: 6219-25. PMID 10037708 DOI: 10.1074/Jbc.274.10.6219 |
0.726 |
|
| 1999 |
Hentze MW, Kulozik AE. A perfect message : RNA surveillance and nonsense-mediated decay Cell. 96: 307-310. PMID 10025395 DOI: 10.1016/S0092-8674(00)80542-5 |
0.322 |
|
| 1999 |
Paraskeva E, Gray NK, Schläger B, Wehr K, Hentze MW. Ribosomal Pausing and Scanning Arrest as Mechanisms of Translational Regulation from Cap-Distal Iron-Responsive Elements Molecular and Cellular Biology. 19: 807-816. PMID 9858603 DOI: 10.1128/Mcb.19.1.807 |
0.519 |
|
| 1999 |
Riedel HD, Muckenthaler MU, Gehrke SG, Mohr I, Brennan K, Herrmann T, Fitscher BA, Hentze MW, Stremmel W. HFE Downregulates Iron Uptake From Transferrin and Induces Iron-Regulatory Protein Activity in Stably Transfected Cells Blood. 94: 3915-3921. DOI: 10.1182/Blood.V94.11.3915.423K27_3915_3921 |
0.531 |
|
| 1998 |
Ostareck-lederer A, Ostareck DH, Hentze MW. Cytoplasmic regulatory functions of the KH-domain proteins hnRNPs K and E1/E2. Trends in Biochemical Sciences. 23: 409-411. PMID 9852755 DOI: 10.1016/S0968-0004(98)01301-2 |
0.362 |
|
| 1998 |
Preiss T, Muckenthaler M, Hentze MW. Poly(A)-tail-promoted translation in yeast: implications for translational control. Rna. 4: 1321-1331. PMID 9814754 DOI: 10.1017/S1355838298980669 |
0.481 |
|
| 1998 |
Muckenthaler M, Gray NK, Hentze MW. IRP-1 Binding to Ferritin mRNA Prevents the Recruitment of the Small Ribosomal Subunit by the Cap-Binding Complex eIF4F Molecular Cell. 2: 383-388. PMID 9774976 DOI: 10.1016/S1097-2765(00)80282-8 |
0.489 |
|
| 1998 |
McKIE AT, Wehr K, Simpson RJ, Peters TJ, Hentze MW, Farzaneh F. Molecular cloning and characterisation of a novel duodenal-specific gene implicated in iron absorption. Biochemical Society Transactions. 26. PMID 9765983 DOI: 10.1042/Bst026S264 |
0.425 |
|
| 1998 |
Pantopoulos K, Hentze MW. Activation of iron regulatory protein-1 by oxidative stress in vitro. Proceedings of the National Academy of Sciences of the United States of America. 95: 10559-63. PMID 9724742 DOI: 10.1073/Pnas.95.18.10559 |
0.681 |
|
| 1998 |
Gregorio ED, Preiss T, Hentze MW. Translational activation of uncapped mRNAs by the central part of human eIF4G is 5' end-dependent. Rna. 4: 828-836. PMID 9671055 DOI: 10.1017/S1355838298980372 |
0.444 |
|
| 1998 |
Muckenthaler M, Gunkel N, Frishman D, Cyrklaff A, Tomancak P, Hentze MW. Iron-regulatory protein-1 (IRP-1) is highly conserved in two invertebrate species--characterization of IRP-1 homologues in Drosophila melanogaster and Caenorhabditis elegans. European Journal of Biochemistry / Febs. 254: 230-7. PMID 9660175 DOI: 10.1046/J.1432-1327.1998.2540230.X |
0.466 |
|
| 1998 |
Thermann R, Neu‐Yilik G, Deters A, Frede U, Wehr K, Hagemeier C, Hentze MW, Kulozik AE. Binary Specification Of Nonsense Codons By Splicing And Cytoplasmic Translation The Embo Journal. 17: 3484-3494. PMID 9628884 DOI: 10.1093/Emboj/17.12.3484 |
0.39 |
|
| 1998 |
Preiss T, Hentze MW. Dual function of the messenger RNA cap structure in poly(A)-tail-promoted translation in yeast Nature. 392: 516-520. PMID 9548259 DOI: 10.1038/33192 |
0.445 |
|
| 1998 |
Paraskeva E, Atzberger A, Hentze MW. A translational repression assay procedure (TRAP) for RNA-protein interactions in vivo. Proceedings of the National Academy of Sciences of the United States of America. 95: 951-956. PMID 9448266 DOI: 10.1073/Pnas.95.3.951 |
0.413 |
|
| 1997 |
Gebauer F, Merendino L, Hentze MW, Valcárcel J. Novel functions for `nuclear factors' in the cytoplasm: theSex-lethalparadigm☆ Seminars in Cell & Developmental Biology. 8: 561-566. PMID 9642170 DOI: 10.1006/Scdb.1997.0181 |
0.406 |
|
| 1997 |
Sachs AB, Sarnow P, Hentze MW. Starting at the beginning, middle, and end: translation initiation in eukaryotes. Cell. 89: 831-8. PMID 9200601 DOI: 10.1016/S0092-8674(00)80268-8 |
0.434 |
|
| 1997 |
Ostareck DH, Ostareck-Lederer A, Wilm M, Thiele BJ, Mann M, Hentze MW. mRNA silencing in erythroid differentiation: hnRNP K and hnRNP E1 regulate 15-lipoxygenase translation from the 3' end. Cell. 89: 597-606. PMID 9160751 DOI: 10.1016/S0092-8674(00)80241-X |
0.411 |
|
| 1997 |
Pantopoulos K, Mueller S, Atzberger A, Ansorge W, Stremmel W, Hentze MW. Differences in the regulation of iron regulatory protein-1 (IRP-1) by extra- and intracellular oxidative stress. The Journal of Biological Chemistry. 272: 9802-8. PMID 9092514 DOI: 10.1074/Jbc.272.15.9802 |
0.666 |
|
| 1997 |
Hentze MW. eIF4G--A Multipurpose Ribosome Adapter? Science. 275: 500-501. PMID 9019810 DOI: 10.1126/Science.275.5299.500 |
0.369 |
|
| 1997 |
Muckenthaler M, Hentze MW. Mechanisms for posttranscriptional regulation by iron-responsive elements and iron regulatory proteins. Progress in Molecular and Subcellular Biology. 18: 93-115. PMID 8994262 DOI: 10.1007/978-3-642-60471-3_5 |
0.479 |
|
| 1996 |
Hentze MW, Kuhn LC. Molecular control of vertebrate iron metabolism: mRNA-based regulatory circuits operated by iron, nitric oxide, and oxidative stress Proceedings of the National Academy of Sciences of the United States of America. 93: 8175-8182. PMID 8710843 DOI: 10.1073/Pnas.93.16.8175 |
0.563 |
|
| 1996 |
Frishman D, Hentze MW. Conservation of Aconitase Residues Revealed by Multiple Sequence Analysis Febs Journal. 239: 197-200. PMID 8706708 DOI: 10.1111/J.1432-1033.1996.0197U.X |
0.408 |
|
| 1996 |
Paraskeva E, Hentze MW. Iron‐sulphur clusters as genetic regulatory switches: the bifunctional iron regulatory protein‐1 Febs Letters. 389: 40-43. PMID 8682202 DOI: 10.1016/0014-5793(96)00574-1 |
0.484 |
|
| 1996 |
Dreyfuss G, Hentze M, Lamond AI. From transcript to protein. Cell. 85: 963-72. PMID 8674124 DOI: 10.1016/S0092-8674(00)81298-2 |
0.411 |
|
| 1996 |
Pantopoulos K, Weiss G, Hentze MW. Nitric oxide and oxidative stress (H2O2) control mammalian iron metabolism by different pathways. Molecular and Cellular Biology. 16: 3781-8. PMID 8668195 DOI: 10.1128/Mcb.16.7.3781 |
0.713 |
|
| 1996 |
Gray NK, Pantopoulos K, Dandekar T, Ackrell BA, Hentze MW. Translational regulation of mammalian and Drosophila citric acid cycle enzymes via iron-responsive elements. Proceedings of the National Academy of Sciences of the United States of America. 93: 4925-30. PMID 8643505 DOI: 10.1073/Pnas.93.10.4925 |
0.736 |
|
| 1996 |
Picard V, Renaudie F, Porcher C, Hentze M, Grandchamp B, Beaumont C. Overexpression of the ferritin H subunit in cultured erythroid cells changes the intracellular iron distribution. Blood. 87: 2057-2064. DOI: 10.1182/Blood.V87.5.2057.2057 |
0.514 |
|
| 1996 |
Wickens M, Goodwin EB, Kimble J, Strickland S, Hentze MW. 15 Translational Control of Developmental Decisions Cold Spring Harbor Monograph Archive. 30: 295-370. DOI: 10.1101/087969458.30.411 |
0.409 |
|
| 1996 |
Hentze MW. Iron-sulfur clusters and oxidant stress responses. Trends in Biochemical Sciences. 21: 282-283. DOI: 10.1016/S0968-0004(96)20019-2 |
0.372 |
|
| 1995 |
Kugler W, Enssle J, Hentze MW, Kulozik AE. Nuclear degradation of nonsense mutated β-globin mRNA: a post-transcriptional mechanism to protect heterozygotes from severe clinical manifestations of β-thalassemia? Nucleic Acids Research. 23: 413-418. PMID 7885837 DOI: 10.1093/Nar/23.3.413 |
0.353 |
|
| 1995 |
Pantopoulos K, Hentze MW. Rapid responses to oxidative stress mediated by iron regulatory protein. The Embo Journal. 14: 2917-24. PMID 7796817 DOI: 10.1002/J.1460-2075.1995.Tb07291.X |
0.701 |
|
| 1995 |
Pantopoulos K, Gray NK, Hentze MW. Differential regulation of two related RNA-binding proteins, iron regulatory protein (IRP) and IRPB. Rna (New York, N.Y.). 1: 155-63. PMID 7585245 |
0.705 |
|
| 1995 |
Dandekar T, Hentze MW. Finding the hairpin in the haystack: searching for RNA motifs. Trends in Genetics : Tig. 11: 45-50. PMID 7536364 DOI: 10.1016/S0168-9525(00)88996-9 |
0.36 |
|
| 1995 |
Pantopoulos K, Hentze MW. Nitric oxide signaling to iron-regulatory protein: direct control of ferritin mRNA translation and transferrin receptor mRNA stability in transfected fibroblasts. Proceedings of the National Academy of Sciences of the United States of America. 92: 1267-71. PMID 7533289 DOI: 10.1073/Pnas.92.5.1267 |
0.739 |
|
| 1995 |
Oria R, Sanchez L, Houston T, Hentze M, Liew F, Brock J. Effect of nitric oxide on expression of transferrin receptor and ferritin and on cellular iron metabolism in K562 human erythroleukemia cells Blood. 85: 2962-2966. DOI: 10.1182/Blood.V85.10.2962.Bloodjournal85102962 |
0.522 |
|
| 1994 |
Pantopoulos K, Weiss G, Hentze MW. Nitric oxide and the post-transcriptional control of cellular iron traffic. Trends in Cell Biology. 4: 82-6. PMID 14731597 DOI: 10.1016/0962-8924(94)90179-1 |
0.736 |
|
| 1994 |
Hentze MW. Enzymes as RNA-binding proteins: a role for (di)nucleotide-binding domains? Trends in Biochemical Sciences. 19: 101-103. PMID 8203013 DOI: 10.1016/0968-0004(94)90198-8 |
0.349 |
|
| 1994 |
Stripecke R, Oliveira CC, Mccarthy JEG, Hentze MW. Proteins binding to 5' untranslated region sites: a general mechanism for translational regulation of mRNAs in human and yeast cells. Molecular and Cellular Biology. 14: 5898-5909. PMID 8065323 DOI: 10.1128/mcb.14.9.5898-5909.1994 |
0.463 |
|
| 1994 |
Johansson HE, Belsham G, Sproat BS, Hentze MW. Target-specific arrest of mRNA translation by antisense 2'-O-alkyloligoribonucleotides. Nucleic Acids Research. 22: 4591-4598. PMID 7984406 DOI: 10.1093/Nar/22.22.4591 |
0.385 |
|
| 1994 |
Pantopoulos K, Johansson HE, Hentze MW. The role of the 5' untranslated region of eukaryotic messenger RNAs in translation and its investigation using antisense technologies. Progress in Nucleic Acid Research and Molecular Biology. 48: 181-238. PMID 7938549 DOI: 10.1016/S0079-6603(08)60856-9 |
0.66 |
|
| 1994 |
Hentze MW. Translational control by iron-responsive elements. Advances in Experimental Medicine and Biology. 356: 119-126. PMID 7887217 DOI: 10.1007/978-1-4615-2554-7_13 |
0.574 |
|
| 1994 |
Weiss G, Goossen B, Doppler W, Fuchs D, Pantopoulos K, Werner-Felmayer G, Grünewald K, Wachter H, Hentze MW. Stimulation of IRE-BP activity of IRF by tetrahydrobiopterin and cytokine dependent induction of nitric oxide synthase. Advances in Experimental Medicine and Biology. 356: 133-9. PMID 7534029 |
0.503 |
|
| 1994 |
Weiss G, Werner-Felmayer G, Werner ER, Grünewald K, Wachter H, Hentze MW. Iron regulates nitric oxide synthase activity by controlling nuclear transcription. Journal of Experimental Medicine. 180: 969-976. PMID 7520477 DOI: 10.1084/Jem.180.3.969 |
0.518 |
|
| 1994 |
Hentze MW. Iron sulfur proteins as effectors and targets of post-transcriptional gene regulation: Iron regulatory protein and its targets Journal of Inorganic Biochemistry. 56: 47. DOI: 10.1016/0162-0134(94)85087-9 |
0.488 |
|
| 1994 |
Gray NK, Hentze MW. Iron regulatory protein prevents binding of the 43S translation pre-initiation complex to ferritin and eALAS mRNAs. The Embo Journal. 13: 3882-3891. DOI: 10.1002/J.1460-2075.1994.Tb06699.X |
0.571 |
|
| 1993 |
Melefors Ö, Hentze MW. Translational regulation by mRNA/protein interactions in eukaryotic cells: Ferritin and beyond Bioessays. 15: 85-90. PMID 8471060 DOI: 10.1002/Bies.950150203 |
0.547 |
|
| 1993 |
Gray NK, Quick S, Goossen B, Constable A, Hirling H, Kühn LC, Hentze MW. Recombinant iron-regulatory factor functions as an iron-responsive-element-binding protein, a translational repressor and an aconitase. A functional assay for translational repression and direct demonstration of the iron switch. Febs Journal. 218: 657-667. PMID 8269957 DOI: 10.1111/J.1432-1033.1993.Tb18420.X |
0.54 |
|
| 1993 |
Oliveira CC, Goossen B, Zanchin NIT, McCarthy JEG, Hentze MW, Stripecke R. Translational repression by the human iron-regulatory factor (IRF) in Saccharomyces cerevisiae. Nucleic Acids Research. 21: 5316-5322. PMID 8265343 DOI: 10.1093/Nar/21.23.5316 |
0.531 |
|
| 1993 |
Enssle J, Kugler W, Hentze MW, Kulozik AE. Determination of mRNA fate by different RNA polymerase II promoters. Proceedings of the National Academy of Sciences of the United States of America. 90: 10091-10095. PMID 8234261 DOI: 10.1073/Pnas.90.21.10091 |
0.396 |
|
| 1993 |
Melefors Ö, Hentze MW. Iron regulatory factor — the conductor of cellular iron regulation Blood Reviews. 7: 251-258. PMID 8130687 DOI: 10.1016/0268-960X(93)90012-S |
0.544 |
|
| 1993 |
Weiss G, Goossen B, Doppler W, Fuchs D, Pantopoulos K, Werner-Felmayer G, Wachter H, Hentze MW. Translational regulation via iron-responsive elements by the nitric oxide/NO-synthase pathway. The Embo Journal. 12: 3651-7. PMID 7504627 DOI: 10.1002/J.1460-2075.1993.Tb06039.X |
0.735 |
|
| 1992 |
Coccia EM, Profita V, Fiorucci G, Romeo G, Affabris E, Testa U, Hentze MW, Battistini A. Modulation of ferritin H-chain expression in Friend erythroleukemia cells: transcriptional and translational regulation by hemin. Molecular and Cellular Biology. 12: 3015-3022. PMID 1620112 DOI: 10.1128/Mcb.12.7.3015 |
0.481 |
|
| 1992 |
Constable A, Quick S, Gray NK, Hentze MW. Modulation of the RNA-binding activity of a regulatory protein by iron in vitro: switching between enzymatic and genetic function? Proceedings of the National Academy of Sciences of the United States of America. 89: 4554-4558. PMID 1584791 DOI: 10.1073/Pnas.89.10.4554 |
0.576 |
|
| 1992 |
Goossen B, Hentze MW. Position is the critical determinant for function of iron-responsive elements as translational regulators. Molecular and Cellular Biology. 12: 1959-1966. PMID 1569933 DOI: 10.1128/Mcb.12.5.1959 |
0.506 |
|
| 1992 |
Stripecke R, Hentze MW. Bacteriophage and spliceosomal proteins function as position-dependent cis/trans repressors of mRNA translation in vitro Nucleic Acids Research. 20: 5555-5564. PMID 1454520 DOI: 10.1093/Nar/20.21.5555 |
0.522 |
|
| 1992 |
Kühn LC, Hentze MW. Coordination of cellular iron metabolism by post-transcriptional gene regulation. Journal of Inorganic Biochemistry. 47: 183-195. PMID 1431880 DOI: 10.1016/0162-0134(92)84064-T |
0.563 |
|
| 1992 |
Coccia E, Profita V, Fiorucci G, Romeo G, Affabris E, Testa U, Hentze M, Battistini A, Rossi G. 24. Modulation of ferritin H-chain expression in Friend erythroleukemia cells: transcriptioaal and translational regulation by hemin Biomedicine & Pharmacotherapy. 46: 250. DOI: 10.1016/0753-3322(92)90109-K |
0.335 |
|
| 1991 |
Hentze MW. Translational regulation of ferritin biosynthesis by iron: a review. Current Studies in Hematology and Blood Transfusion. 58: 115-126. PMID 1954759 DOI: 10.1159/000419349 |
0.496 |
|
| 1991 |
Hentze MW. Determinants and regulation of cytoplasmic mRNA stability in eukaryotic cells. Biochimica Et Biophysica Acta. 1090: 281-292. PMID 1954250 DOI: 10.1016/0167-4781(91)90191-N |
0.394 |
|
| 1991 |
Hentze MW, Argos P. Homology between IRE-BP, a regulatory RNA-binding protein, aconitase, and isopropylmalate isomerase Nucleic Acids Research. 19: 1739-1740. PMID 1903202 DOI: 10.1093/Nar/19.8.1739 |
0.471 |
|
| 1991 |
Dandekar T, Stripecke R, Gray N, Goossen B, Constable A, Johansson H, Hentze M. Identification of a novel iron-responsive element in murine and human erythroid delta-aminolevulinic acid synthase mRNA. The Embo Journal. 10: 1903-1909. DOI: 10.1002/J.1460-2075.1991.Tb07716.X |
0.546 |
|
| 1990 |
Hentze MW, Goossen B, Caughman SW. Complex formation between a cytoplasmic protein and the ferritin mRNA regulates translation initiation. Molecular Biology Reports. 14: 61-61. PMID 2113990 DOI: 10.1007/Bf00360416 |
0.442 |
|
| 1990 |
Goossen B, Caughman SW, Harford JB, Klausner RD, Hentze MW. Translational repression by a complex between the iron-responsive element of ferritin mRNA and its specific cytoplasmic binding protein is position-dependent in vivo. The Embo Journal. 9: 4127-4133. DOI: 10.1002/J.1460-2075.1990.Tb07635.X |
0.563 |
|
| 1989 |
Hentze MW, Seuanez HN, O'Brien SJ, Harford JB, Klausner RD. Chromosomal localization of nucleic acid-binding proteins by affinity mapping: Assignment of the IRE-binding protein gene to human chromosome 9 Nucleic Acids Research. 17: 6103-6108. PMID 2771641 DOI: 10.1093/Nar/17.15.6103 |
0.469 |
|
| 1989 |
Hentze MW, Rouault TA, Harford JB, Klausner RD. Oxidation-reduction and the molecular mechanism of a regulatory RNA-protein interaction. Science (New York, N.Y.). 244: 357-9. PMID 2711187 DOI: 10.1126/Science.2711187 |
0.557 |
|
| 1989 |
Haile DJ, Hentze MW, Rouault TA, Harford JB, Klausner RD. Regulation of interaction of the iron-responsive element binding protein with iron-responsive RNA elements Molecular and Cellular Biology. 9: 5055-50619. PMID 2601708 DOI: 10.1128/Mcb.9.11.5055 |
0.515 |
|
| 1989 |
Koeller DM, Casey JL, Hentze MW, Gerhardt EM, Chan LN, Klausner RD, Harford JB. A cytosolic protein binds to structural elements within the iron regulatory region of the transferrin receptor mRNA. Proceedings of the National Academy of Sciences of the United States of America. 86: 3574-8. PMID 2498873 DOI: 10.1073/Pnas.86.10.3574 |
0.545 |
|
| 1989 |
Rouault TA, Hentze MW, Haile DJ, Harford JB, Klausner RD. The iron-responsive element binding protein: A method for the affinity purification of a regulatory RNA-binding protein Proceedings of the National Academy of Sciences of the United States of America. 86: 5768-5772. PMID 2474819 DOI: 10.1073/Pnas.86.15.5768 |
0.497 |
|
| 1988 |
Rouault TA, Hentze MW, Caughman SW, Harford JB, Klausner RD. Binding of a cytosolic protein to the iron-responsive element of human ferritin messenger RNA. Science (New York, N.Y.). 241: 1207-10. PMID 3413484 DOI: 10.1126/Science.3413484 |
0.559 |
|
| 1988 |
Hentze MW, Caughman SW, Casey JL, Koeller DM, Rouault TA, Harford JB, Klausner RD. A model for the structure and functions of iron-responsive elements. Gene. 72: 201-8. PMID 3266604 DOI: 10.1016/0378-1119(88)90145-X |
0.546 |
|
| 1988 |
Casey JL, Hentze MW, Koeller DM, Caughman SW, Rouault TA, Klausner RD, Harford JB. Iron-responsive elements: regulatory RNA sequences that control mRNA levels and translation. Science (New York, N.Y.). 240: 924-8. PMID 2452485 DOI: 10.1126/Science.2452485 |
0.564 |
|
| 1987 |
Hentze MW, Caughman SW, Rouault TA, Barriocanal JG, Dancis A, Harford JB, Klausner RD. Identification of the iron-responsive element for the translational regulation of human ferritin mRNA. Science (New York, N.Y.). 238: 1570-3. PMID 3685996 DOI: 10.1126/Science.3685996 |
0.559 |
|
| 1987 |
Hentze MW, Rouault TA, Caughman SW, Dancis A, Harford JB, Klausner RD. A cis-acting element is necessary and sufficient for translational regulation of human ferritin expression in response to iron. Proceedings of the National Academy of Sciences of the United States of America. 84: 6730-4. PMID 3477805 DOI: 10.1073/Pnas.84.19.6730 |
0.523 |
|
| 1987 |
Rouault TA, Hentze MW, Dancis A, Caughman W, Harford JB, Klausner RD. Influence of altered transcription on the translational control of human ferritin expression Proceedings of the National Academy of Sciences of the United States of America. 84: 6335-6339. PMID 3476949 DOI: 10.1073/Pnas.84.18.6335 |
0.497 |
|
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