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Jason C. Wong - Publications

Affiliations: 
2004 Harvard University, Cambridge, MA, United States 
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14 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Lin X, Chen W, Qiu Z, Guo L, Zhu W, Li W, Wang Z, Zhang W, Zhang Z, Rong Y, Zhang M, Yu L, Zhong S, Zhao R, Wu X, ... Wong JC, et al. Design and synthesis of orally bioavailable aminopyrrolidinone histone deacetylase 6 inhibitors. Journal of Medicinal Chemistry. 58: 2809-20. PMID 25734520 DOI: 10.1021/jm502011f  0.445
2014 Tang G, Wong JC, Zhang W, Wang Z, Zhang N, Peng Z, Zhang Z, Rong Y, Li S, Zhang M, Yu L, Feng T, Zhang X, Wu X, Wu JZ, et al. Identification of a novel aminotetralin class of HDAC6 and HDAC8 selective inhibitors. Journal of Medicinal Chemistry. 57: 8026-34. PMID 25238284 DOI: 10.1021/jm5008962  0.438
2011 Wong JC, Guo L, Peng Z, Zhang W, Zhang N, Lai W, Zhang Z, Zhang C, Zhang X, Song S, Pan D, Xie C, Li J, Ning Z, Lu X, et al. Application of p21 and klf2 reporter gene assays to identify selective histone deacetylase inhibitors for cancer therapy. Bioorganic & Medicinal Chemistry Letters. 21: 110-6. PMID 21145737 DOI: 10.1016/J.Bmcl.2010.11.063  0.355
2006 Cheng Q, Balzer E, Miller SM, Yoshida M, Wong JC. EFFECT OF HISTONE DEACETYLASE INHIBITORS ON TUBULIN ACETYLATION AND DEVELOPMENT IN VOLVOX CARTERI (VOLVOCALES)1 Journal of Phycology. 42: 417-422. DOI: 10.1111/J.1529-8817.2006.00200.X  0.383
2005 Hideshima T, Bradner JE, Wong J, Chauhan D, Richardson P, Schreiber SL, Anderson KC. Small-molecule inhibition of proteasome and aggresome function induces synergistic antitumor activity in multiple myeloma. Proceedings of the National Academy of Sciences of the United States of America. 102: 8567-72. PMID 15937109 DOI: 10.1073/Pnas.0503221102  0.599
2005 Marcus AI, Zhou J, O'Brate A, Hamel E, Wong J, Nivens M, El-Naggar A, Yao TP, Khuri FR, Giannakakou P. The synergistic combination of the farnesyl transferase inhibitor lonafarnib and paclitaxel enhances tubulin acetylation and requires a functional tubulin deacetylase. Cancer Research. 65: 3883-93. PMID 15867388 DOI: 10.1158/0008-5472.Can-04-3757  0.37
2004 Haggarty SJ, Clemons PA, Wong JC, Schreiber SL. Mapping chemical space using molecular descriptors and chemical genetics: deacetylase inhibitors. Combinatorial Chemistry & High Throughput Screening. 7: 669-76. PMID 15578929 DOI: 10.2174/1386207043328319  0.724
2004 Wong JC, Sternson SM, Louca JB, Hong R, Schreiber SL. Modular synthesis and preliminary biological evaluation of stereochemically diverse 1,3-dioxanes. Chemistry & Biology. 11: 1279-91. PMID 15380188 DOI: 10.1016/J.Chembiol.2004.07.012  0.699
2003 Koeller KM, Haggarty SJ, Perkins BD, Leykin I, Wong JC, Kao MC, Schreiber SL. Chemical genetic modifier screens: small molecule trichostatin suppressors as probes of intracellular histone and tubulin acetylation. Chemistry & Biology. 10: 397-410. PMID 12770822 DOI: 10.1016/S1074-5521(03)00093-0  0.737
2003 Haggarty SJ, Koeller KM, Wong JC, Butcher RA, Schreiber SL. Multidimensional chemical genetic analysis of diversity-oriented synthesis-derived deacetylase inhibitors using cell-based assays. Chemistry & Biology. 10: 383-96. PMID 12770821 DOI: 10.1016/S1074-5521(03)00095-4  0.752
2003 Wong JC, Hong R, Schreiber SL. Structural biasing elements for in-cell histone deacetylase paralog selectivity. Journal of the American Chemical Society. 125: 5586-7. PMID 12733869 DOI: 10.1021/Ja0341440  0.555
2003 Haggarty SJ, Koeller KM, Wong JC, Grozinger CM, Schreiber SL. Domain-selective small-molecule inhibitor of histone deacetylase 6 (HDAC6)-mediated tubulin deacetylation. Proceedings of the National Academy of Sciences of the United States of America. 100: 4389-94. PMID 12677000 DOI: 10.1073/Pnas.0430973100  0.721
2001 Sternson SM, Wong JC, Grozinger CM, Schreiber SL. Synthesis of 7200 small molecules based on a substructural analysis of the histone deacetylase inhibitors trichostatin and trapoxin. Organic Letters. 3: 4239-42. PMID 11784187 DOI: 10.1021/Ol016915F  0.726
2001 Sternson SM, Louca JB, Wong JC, Schreiber SL. Split--pool synthesis of 1,3-dioxanes leading to arrayed stock solutions of single compounds sufficient for multiple phenotypic and protein-binding assays. Journal of the American Chemical Society. 123: 1740-7. PMID 11456775 DOI: 10.1021/Ja0036108  0.691
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