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Simone Brixius-Anderko - Publications

Affiliations: 
2017- Medicinal Chemistry University of Michigan, Ann Arbor, Ann Arbor, MI 
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11 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Loomis CL, Brixius-Anderko S, Scott EE. Redox partner adrenodoxin alters cytochrome P450 11B1 ligand binding and inhibition. Journal of Inorganic Biochemistry. 235: 111934. PMID 35952394 DOI: 10.1016/j.jinorgbio.2022.111934  0.599
2021 Brixius-Anderko S, Scott EE. Aldosterone Synthase Structure With Cushing Disease Drug LCI699 Highlights Avenues for Selective CYP11B Drug Design. Hypertension (Dallas, Tex. : 1979). HYPERTENSIONAHA12117. PMID 34247511 DOI: 10.1161/HYPERTENSIONAHA.121.17615  0.62
2021 Brixius-Anderko S, Scott EE. Structural and functional insights into aldosterone synthase interaction with its redox partner protein adrenodoxin. The Journal of Biological Chemistry. 100794. PMID 34015331 DOI: 10.1016/j.jbc.2021.100794  0.609
2020 Wróbel TM, Rogova O, Andersen KL, Yadav R, Brixius-Anderko S, Scott EE, Olsen L, Jørgensen FS, Björkling F. Discovery of Novel Non-Steroidal Cytochrome P450 17A1 Inhibitors as Potential Prostate Cancer Agents. International Journal of Molecular Sciences. 21. PMID 32660148 DOI: 10.3390/Ijms21144868  0.555
2020 König L, Szczesny S, Brixius-Anderko S, Bernhardt R, Hannemann F. Mixed-culture fermentation for enhanced C21-hydroxylation of glucocorticoids. Journal of Biotechnology. PMID 32246945 DOI: 10.1016/J.Jbiotec.2020.03.008  0.337
2020 Brixius-Anderko S, Scott EE. Abstract MP11: Aldosterone Synthase Structure With Cushing’s Disease Drug Osilodrostat Provides Clues For Treatment Of Primary Aldosteronism Hypertension. 76. DOI: 10.1161/Hyp.76.Suppl_1.Mp11  0.548
2020 Brixius-Anderko S, Scott E. Structural and Functional Insights into Aldosterone Synthase Interaction with Ligands and Redox Partner Proteins for Enhanced Treatment of Hypertension The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.03565  0.555
2018 Brixius-Anderko S, Scott EE. Structure of human cortisol-producing cytochrome P450 11B1 bound to the breast cancer drug fadrozole provides insights for drug design. The Journal of Biological Chemistry. PMID 30425102 DOI: 10.1074/Jbc.Ra118.006214  0.632
2017 Malikova J, Brixius-Anderko S, Udhane SS, Parween S, Dick B, Bernhardt R, Pandey AV. CYP17A1 inhibitor abiraterone, an anti-prostate cancer drug, also inhibits the 21-hydroxylase activity of CYP21A2. The Journal of Steroid Biochemistry and Molecular Biology. PMID 28893623 DOI: 10.1016/j.jsbmb.2017.09.007  0.422
2016 Schiffer L, Müller AR, Hobler A, Brixius-Anderko S, Zapp J, Hannemann F, Bernhardt R. Biotransformation of the mineralocorticoid receptor antagonists spironolactone and canrenone by human CYP11B1 and CYP11B2: Characterization of the products and their influence on mineralocorticoid receptor transactivation. The Journal of Steroid Biochemistry and Molecular Biology. 163: 68-76. PMID 27125452 DOI: 10.1016/j.jsbmb.2016.04.004  0.305
2016 Schiffer L, Brixius-Anderko S, Hannemann F, Zapp J, Neunzig J, Thevis M, Bernhardt R. Metabolism of Oral Turinabol by Human Steroid Hormone-Synthesizing Cytochrome P450 Enzymes. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 44: 227-37. PMID 26658226 DOI: 10.1124/dmd.115.066829  0.34
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