Myriam Aouadi - Publications

Affiliations: 
Karolinska Institute, Stockholm, Sweden 

45 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Krejčová G, Morgantini C, Zemanová H, Lauschke VM, Kovářová J, Kubásek J, Nedbalová P, Kamps-Hughes N, Moos M, Aouadi M, Doležal T, Bajgar A. Macrophage-derived insulin antagonist ImpL2 induces lipoprotein mobilization upon bacterial infection. The Embo Journal. e114086. PMID 37807855 DOI: 10.15252/embj.2023114086  0.326
2022 Holmer M, Hagström H, Chen P, Danielsson O, Aouadi M, Rydén M, Stål P. Associations between subcutaneous adipocyte hypertrophy and nonalcoholic fatty liver disease. Scientific Reports. 12: 20519. PMID 36443373 DOI: 10.1038/s41598-022-24482-1  0.318
2022 Barreby E, Chen P, Aouadi M. Macrophage functional diversity in NAFLD - more than inflammation. Nature Reviews. Endocrinology. PMID 35534573 DOI: 10.1038/s41574-022-00675-6  0.343
2022 Maqdasy S, Lecoutre S, Renzi G, Frendo-Cumbo S, Rizo-Roca D, Moritz T, Juvany M, Hodek O, Gao H, Couchet M, Witting M, Kerr A, Bergo MO, Choudhury RP, Aouadi M, et al. Impaired phosphocreatine metabolism in white adipocytes promotes inflammation. Nature Metabolism. 4: 190-202. PMID 35165448 DOI: 10.1038/s42255-022-00525-9  0.41
2021 Li Q, Hagberg CE, Silva Cascales H, Lang S, Hyvönen MT, Salehzadeh F, Chen P, Alexandersson I, Terezaki E, Harms MJ, Kutschke M, Arifen N, Krämer N, Aouadi M, Knibbe C, et al. Obesity and hyperinsulinemia drive adipocytes to activate a cell cycle program and senesce. Nature Medicine. PMID 34608330 DOI: 10.1038/s41591-021-01501-8  0.347
2021 Blériot C, Barreby E, Dunsmore G, Ballaire R, Chakarov S, Ficht X, De Simone G, Andreata F, Fumagalli V, Guo W, Wan G, Gessain G, Khalilnezhad A, Zhang XM, Ang N, ... ... Aouadi M, et al. A subset of Kupffer cells regulates metabolism through the expression of CD36. Immunity. PMID 34469775 DOI: 10.1016/j.immuni.2021.08.006  0.351
2021 Huang Z, Liang N, Goñi S, Damdimopoulos A, Wang C, Ballaire R, Jager J, Niskanen H, Han H, Jakobsson T, Bracken AP, Aouadi M, Venteclef N, Kaikkonen MU, Fan R, et al. The corepressors GPS2 and SMRT control enhancer and silencer remodeling via eRNA transcription during inflammatory activation of macrophages. Molecular Cell. PMID 33503407 DOI: 10.1016/j.molcel.2020.12.040  0.365
2020 Luo J, Weaver MS, Fitzgibbons TP, Aouadi M, Czech MP, Allen MD. Immunotherapy for Infarcts: Postinfarction Macrophage Modulation Using Intramyocardial Microparticle Delivery of Small Interfering RNA. Bioresearch Open Access. 9: 258-268. PMID 33376632 DOI: 10.1089/biores.2020.0037  0.524
2020 Oses C, Aouadi M. Kupffer Cell and Hepatocyte Isolation from a Single Mouse Liver by Gradient Centrifugation. Methods in Molecular Biology (Clifton, N.J.). 2164: 1-10. PMID 32607877 DOI: 10.1007/978-1-0716-0704-6_1  0.307
2020 Azzimato V, Jager J, Chen P, Morgantini C, Levi L, Barreby E, Sulen A, Oses C, Willerbrords J, Xu C, Li X, Shen JX, Akbar N, Haag L, Ellis E, ... ... Aouadi M, et al. Liver macrophages inhibit the endogenous antioxidant response in obesity-associated insulin resistance. Science Translational Medicine. 12. PMID 32102936 DOI: 10.1126/Scitranslmed.Aaw9709  0.491
2019 Morgantini C, Jager J, Li X, Levi L, Azzimato V, Sulen A, Barreby E, Xu C, Tencerova M, Näslund E, Kumar C, Verdeguer F, Straniero S, Hultenby K, Björkström NK, ... ... Aouadi M, et al. Liver macrophages regulate systemic metabolism through non-inflammatory factors. Nature Metabolism. 1: 445-459. PMID 32694874 DOI: 10.1038/s42255-019-0044-9  0.403
2019 Petrus P, Lecoutre S, Dollet L, Wiel C, Sulen A, Gao H, Tavira B, Laurencikiene J, Rooyackers O, Checa A, Douagi I, Wheelock CE, Arner P, McCarthy M, Bergo MO, ... ... Aouadi M, et al. Glutamine Links Obesity to Inflammation in Human White Adipose Tissue. Cell Metabolism. PMID 31866443 DOI: 10.1016/J.Cmet.2019.11.019  0.464
2019 Akbar N, Azzimato V, Choudhury RP, Aouadi M. Extracellular vesicles in metabolic disease. Diabetologia. PMID 31690986 DOI: 10.1007/S00125-019-05014-5  0.368
2019 Petkevicius K, Virtue S, Bidault G, Jenkins B, Çubuk C, Morgantini C, Aouadi M, Dopazo J, Serlie M, Koulman A, Vidal-Puig A. Accelerated phosphatidylcholine turnover in macrophages promotes adipose tissue inflammation in obesity. Elife. 8. PMID 31418690 DOI: 10.7554/Elife.47990  0.538
2019 Barreby E, Sulen A, Aouadi M. Glucan-Encapsulated siRNA Particles (GeRPs) for Specific Gene Silencing in Adipose Tissue Macrophages. Methods in Molecular Biology (Clifton, N.J.). 1951: 49-57. PMID 30825143 DOI: 10.1007/978-1-4939-9130-3_4  0.562
2019 Petkevicius K, Virtue S, Bidault G, Jenkins B, Çubuk C, Morgantini C, Aouadi M, Dopazo J, Serlie MJ, Koulman A, Vidal-Puig A. Author response: Accelerated phosphatidylcholine turnover in macrophages promotes adipose tissue inflammation in obesity Elife. DOI: 10.7554/Elife.47990.039  0.481
2017 Acosta JR, Joost S, Karlsson K, Ehrlund A, Li X, Aouadi M, Kasper M, Arner P, Rydén M, Laurencikiene J. Single cell transcriptomics suggest that human adipocyte progenitor cells constitute a homogeneous cell population. Stem Cell Research & Therapy. 8: 250. PMID 29116032 DOI: 10.1186/S13287-017-0701-4  0.348
2017 Jourdan T, Nicoloro SM, Zhou Z, Shen Y, Liu J, Coffey NJ, Cinar R, Godlewski G, Gao B, Aouadi M, Czech MP, Kunos G. Decreasing CB1 receptor signaling in Kupffer cells improves insulin sensitivity in obese mice. Molecular Metabolism. 6: 1517-1528. PMID 29107297 DOI: 10.1016/J.Molmet.2017.08.011  0.658
2017 Verdeguer F, Aouadi M. Macrophage heterogeneity and energy metabolism. Experimental Cell Research. 360: 35-40. PMID 28341447 DOI: 10.1016/J.Yexcr.2017.03.043  0.416
2016 Jager J, Aparicio-Vergara M, Aouadi M. Liver innate immune cells and insulin resistance: the multiple facets of Kupffer cells. Journal of Internal Medicine. 280: 209-20. PMID 26864622 DOI: 10.1111/Joim.12483  0.476
2016 Cohen JL, Shen Y, Aouadi M, Vangala P, Tencerova M, Amano SU, Nicoloro SM, Yawe JC, Czech MP. Peptide- and Amine-Modified Glucan Particles for the Delivery of Therapeutic siRNA. Molecular Pharmaceutics. PMID 26815386 DOI: 10.1021/Acs.Molpharmaceut.5B00831  0.78
2015 Roth Flach RJ, Skoura A, Matevossian A, Danai LV, Zheng W, Cortes C, Bhattacharya SK, Aouadi M, Hagan N, Yawe JC, Vangala P, Menendez LG, Cooper MP, Fitzgibbons TP, Buckbinder L, et al. Endothelial protein kinase MAP4K4 promotes vascular inflammation and atherosclerosis. Nature Communications. 6: 8995. PMID 26688060 DOI: 10.1038/Ncomms9995  0.712
2015 Tencerova M, Aouadi M, Vangala P, Nicoloro SM, Yawe JC, Cohen JL, Shen Y, Garcia-Menendez L, Pedersen DJ, Gallagher-Dorval K, Perugini RA, Gupta OT, Czech MP. Activated Kupffer cells inhibit insulin sensitivity in obese mice. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 29: 2959-69. PMID 25805830 DOI: 10.1096/Fj.15-270496  0.767
2014 Aouadi M. HIF-2α blows out the flames of adipose tissue macrophages to keep obesity in a safe zone. Diabetes. 63: 3169-71. PMID 25249641 DOI: 10.2337/Db14-0878  0.503
2014 Aouadi M, Vangala P, Yawe JC, Tencerova M, Nicoloro SM, Cohen JL, Shen Y, Czech MP. Lipid storage by adipose tissue macrophages regulates systemic glucose tolerance. American Journal of Physiology. Endocrinology and Metabolism. 307: E374-83. PMID 24986598 DOI: 10.1152/Ajpendo.00187.2014  0.784
2014 Amano SU, Cohen JL, Vangala P, Tencerova M, Nicoloro SM, Yawe JC, Shen Y, Czech MP, Aouadi M. Local proliferation of macrophages contributes to obesity-associated adipose tissue inflammation. Cell Metabolism. 19: 162-71. PMID 24374218 DOI: 10.1016/J.Cmet.2013.11.017  0.795
2013 Jourdan T, Godlewski G, Cinar R, Bertola A, Szanda G, Liu J, Tam J, Han T, Mukhopadhyay B, Skarulis MC, Ju C, Aouadi M, Czech MP, Kunos G. Activation of the Nlrp3 inflammasome in infiltrating macrophages by endocannabinoids mediates beta cell loss in type 2 diabetes. Nature Medicine. 19: 1132-40. PMID 23955712 DOI: 10.1038/Nm.3265  0.614
2013 Aouadi M, Tencerova M, Vangala P, Yawe JC, Nicoloro SM, Amano SU, Cohen JL, Czech MP. Gene silencing in adipose tissue macrophages regulates whole-body metabolism in obese mice. Proceedings of the National Academy of Sciences of the United States of America. 110: 8278-83. PMID 23630254 DOI: 10.1073/Pnas.1300492110  0.806
2013 Guo CA, Kogan S, Amano SU, Wang M, Dagdeviren S, Friedline RH, Aouadi M, Kim JK, Czech MP. CD40 deficiency in mice exacerbates obesity-induced adipose tissue inflammation, hepatic steatosis, and insulin resistance. American Journal of Physiology. Endocrinology and Metabolism. 304: E951-63. PMID 23482447 DOI: 10.1152/Ajpendo.00514.2012  0.647
2013 Czech MP, Tencerova M, Pedersen DJ, Aouadi M. Insulin signalling mechanisms for triacylglycerol storage. Diabetologia. 56: 949-64. PMID 23443243 DOI: 10.1007/S00125-013-2869-1  0.624
2013 Wang M, Amano SU, Roth Flach RJ, Chawla A, Aouadi M, Czech MP. Identification of map4k4 as a novel suppressor of skeletal muscle differentiation Molecular and Cellular Biology. 33: 678-687. PMID 23207904 DOI: 10.1128/Mcb.00618-12  0.566
2011 Fitzgibbons TP, Kogan S, Aouadi M, Hendricks GM, Straubhaar J, Czech MP. Similarity of mouse perivascular and brown adipose tissues and their resistance to diet-induced inflammation. American Journal of Physiology. Heart and Circulatory Physiology. 301: H1425-37. PMID 21765057 DOI: 10.1152/Ajpheart.00376.2011  0.675
2011 Czech MP, Aouadi M, Tesz GJ. RNAi-based therapeutic strategies for metabolic disease. Nature Reviews. Endocrinology. 7: 473-84. PMID 21502982 DOI: 10.1038/Nrendo.2011.57  0.785
2011 Tesz GJ, Aouadi M, Prot M, Nicoloro SM, Boutet E, Amano SU, Goller A, Wang M, Guo CA, Salomon WE, Virbasius JV, Baum RA, O'Connor MJ, Soto E, Ostroff GR, et al. Glucan particles for selective delivery of siRNA to phagocytic cells in mice. The Biochemical Journal. 436: 351-62. PMID 21418037 DOI: 10.1042/Bj20110352  0.758
2011 Huang W, Ghisletti S, Saijo K, Gandhi M, Aouadi M, Tesz GJ, Zhang DX, Yao J, Czech MP, Goode BL, Rosenfeld MG, Glass CK. Coronin 2A mediates actin-dependent de-repression of inflammatory response genes. Nature. 470: 414-8. PMID 21331046 DOI: 10.1038/Nature09703  0.776
2009 Aouadi M, Tesz GJ, Nicoloro SM, Wang M, Chouinard M, Soto E, Ostroff GR, Czech MP. Orally delivered siRNA targeting macrophage Map4k4 suppresses systemic inflammation Nature. 458: 1180-1184. PMID 19407801 DOI: 10.1038/Nature07774  0.796
2007 Aouadi M, Jager J, Laurent K, Gonzalez T, Cormont M, Binétruy B, Le Marchand-Brustel Y, Tanti JF, Bost F. p38MAP Kinase activity is required for human primary adipocyte differentiation Febs Letters. 581: 5591-5596. PMID 17997987 DOI: 10.1016/J.Febslet.2007.10.064  0.348
2007 Puri V, Konda S, Ranjit S, Aouadi M, Chawla A, Chouinard M, Chakladar A, Czech MP. Fat-specific protein 27, a novel lipid droplet protein that enhances triglyceride storage Journal of Biological Chemistry. 282: 34213-34218. PMID 17884815 DOI: 10.1074/Jbc.M707404200  0.716
2007 Binétruy B, Heasley L, Bost F, Caron L, Aouadi M. Concise review: regulation of embryonic stem cell lineage commitment by mitogen-activated protein kinases. Stem Cells (Dayton, Ohio). 25: 1090-5. PMID 17218395 DOI: 10.1634/Stemcells.2006-0612  0.344
2006 Le Marchand-Brustel Y, Gual P, Aouadi M, Grémeaux T, Binétruy B, Bost F, Tanti JF. [Obesity, diabetes and insulin resistance. Alterations of insulin signalling]. Journal De La Societe De Biologie. 200: 93-7. PMID 17144167 DOI: 10.1051/Jbio:2006012  0.412
2006 Prot M, Heripret L, Cardot-Leccia N, Perrin C, Aouadi M, Lavrut T, Garraffo R, Dellamonica P, Durant J, Le Marchand-Brustel Y, Binétruy B. Long-term treatment with lopinavir-ritonavir induces a reduction in peripheral adipose depots in mice Antimicrobial Agents and Chemotherapy. 50: 3998-4004. PMID 17000748 DOI: 10.1128/Aac.00222-07  0.378
2006 Aouadi M, Binetruy B, Caron L, Le Marchand-Brustel Y, Bost F. Role of MAPKs in development and differentiation: lessons from knockout mice. Biochimie. 88: 1091-8. PMID 16854512 DOI: 10.1016/J.Biochi.2006.06.003  0.396
2006 Aouadi M, Laurent K, Prot M, Le Marchand-Brustel Y, Binétruy B, Bost F. Inhibition of p38MAPK increases adipogenesis from embryonic to adult stages Diabetes. 55: 281-289. PMID 16443758 DOI: 10.2337/Diabetes.55.02.06.Db05-0963  0.481
2005 Bost F, Aouadi M, Caron L, Binétruy B. The role of MAPKs in adipocyte differentiation and obesity. Biochimie. 87: 51-6. PMID 15733737 DOI: 10.1016/J.Biochi.2004.10.018  0.475
2005 Bost F, Aouadi M, Caron L, Even P, Belmonte N, Prot M, Dani C, Hofman P, Pagès G, Pouysségur J, Le Marchand-Brustel Y, Binétruy B. The extracellular signal-regulated kinase isoform ERK1 is specifically required for in vitro and in vivo adipogenesis. Diabetes. 54: 402-11. PMID 15677498 DOI: 10.2337/Diabetes.54.2.402  0.517
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