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Ming-Feng Tsai, Ph.D. - Publications

Affiliations: 
2019- Physiology and Biophysics University of Colorado School of Medicine, Aurora, CO, United States 
Area:
Membrane biochemistry, electrophysiology, cryo-electron microscopy, live-cell imaging
Website:
https://medschool.cuanschutz.edu/physiology/faculty/ming-feng-tsai
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29 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 He Z, Tu YC, Tsai CW, Mount J, Zhang J, Tsai MF, Yuan P. Structure and function of the human mitochondrial MRS2 channel. Biorxiv : the Preprint Server For Biology. PMID 37645897 DOI: 10.1101/2023.08.12.553106  0.457
2023 Tu YC, Chao FY, Tsai MF. Mechanisms of dual modulatory effects of spermine on the mitochondrial calcium uniporter complex. Biorxiv : the Preprint Server For Biology. PMID 37333420 DOI: 10.1101/2023.06.06.543936  0.453
2023 Tsai CW, Liu TY, Chao FY, Tu YC, Rodriguez MX, Van Keuren AM, Ma Z, Bankston J, Tsai MF. Evidence supporting the MICU1 occlusion mechanism and against the potentiation model in the mitochondrial calcium uniporter complex. Proceedings of the National Academy of Sciences of the United States of America. 120: e2217665120. PMID 37036971 DOI: 10.1073/pnas.2217665120  0.499
2022 Tsai CW, Rodriguez MX, Van Keuren AM, Phillips CB, Shushunov HM, Lee JE, Garcia AM, Ambardekar AV, Cleveland JC, Reisz JA, Proenza C, Chatfield KC, Tsai MF. Mechanisms and significance of tissue-specific MICU regulation of the mitochondrial calcium uniporter complex. Molecular Cell. 82: 3661-3676.e8. PMID 36206740 DOI: 10.1016/j.molcel.2022.09.006  0.712
2021 Rodriguez MX, Van Keuren AM, Tsai MF. Quantitative assays to measure the transport activity of the mitochondrial calcium uniporter in cell lines or oocytes. Star Protocols. 2: 100979. PMID 34877549 DOI: 10.1016/j.xpro.2021.100979  0.407
2020 Van Keuren AM, Tsai CW, Balderas E, Rodriguez MX, Chaudhuri D, Tsai MF. Mechanisms of EMRE-Dependent MCU Opening in the Mitochondrial Calcium Uniporter Complex. Cell Reports. 33: 108486. PMID 33296646 DOI: 10.1016/j.celrep.2020.108486  0.492
2020 Fan M, Zhang J, Tsai CW, Orlando BJ, Rodriguez M, Xu Y, Liao M, Tsai MF, Feng L. Structure and mechanism of the mitochondrial Ca uniporter holocomplex. Nature. 582: 129-133. PMID 32494073 DOI: 10.1038/S41586-020-2309-6  0.437
2020 Van Keuren AM, Tsai C, Tsai M. Mechanisms of EMRE Activation of the Mitochondrial Calcium Uniporter Biophysical Journal. 118: 174a. DOI: 10.1016/j.bpj.2019.11.1061  0.304
2020 Tsai C, Tsai M. Mechanisms of MICU1 Regulation of the Mitochondrial Calcium Uniporter Complex Biophysical Journal. 118: 174a. DOI: 10.1016/j.bpj.2019.11.1060  0.33
2019 Phillips CB, Tsai CW, Tsai MF. The conserved aspartate ring of MCU mediates MICU1 binding and regulation in the mitochondrial calcium uniporter complex. Elife. 8. PMID 30638448 DOI: 10.7554/eLife.41112  0.719
2018 Tsai CW, Tsai MF. Electrical recordings of the mitochondrial calcium uniporter in oocytes. The Journal of General Physiology. PMID 29891485 DOI: 10.1085/jgp.201812015  0.499
2017 Tsai CW, Wu Y, Pao PC, Phillips CB, Williams C, Miller C, Ranaghan M, Tsai MF. Proteolytic control of the mitochondrial calcium uniporter complex. Proceedings of the National Academy of Sciences of the United States of America. PMID 28396416 DOI: 10.1073/Pnas.1702938114  0.743
2017 Tsai MF, Phillips CB, Ranaghan M, Tsai CW, Wu Y, Willliams C, Miller C. Correction: Dual functions of a small regulatory subunit in the mitochondrial calcium uniporter complex. Elife. 6. PMID 28253172 DOI: 10.7554/Elife.26228  0.688
2017 Tsai M, Miller C. Safety Upgrades of the Mitochondrial Calcium Uniporter Biophysical Journal. 112: 485a. DOI: 10.1016/j.bpj.2016.11.2623  0.417
2016 Tsai MF, Phillips CB, Ranaghan M, Tsai CW, Wu Y, Willliams C, Miller C. Dual functions of a small regulatory subunit in the mitochondrial calcium uniporter complex. Elife. 5. PMID 27099988 DOI: 10.7554/Elife.15545  0.735
2016 Tsai M, Miller C. Molecular Assembly of the Mitochondrial Calcium Uniporter Complex Biophysical Journal. 110: 433a. DOI: 10.1016/j.bpj.2015.11.2336  0.439
2015 Yu Y, Tsai MF, Yu WP, Chen TY. Modulation of the slow/common gating of CLC channels by intracellular cadmium. The Journal of General Physiology. 146: 495-508. PMID 26621774 DOI: 10.1085/jgp.201511413  0.625
2015 Stockbridge RB, Tsai MF. Lipid reconstitution and recording of recombinant ion channels. Methods in Enzymology. 556: 385-404. PMID 25857792 DOI: 10.1016/bs.mie.2014.12.028  0.614
2015 Tsai M, Phillips C, Miller C. Mitochondrial Calcium and Bioenergetics Controlled by Tight Coordination of MCU and NCLX Biophysical Journal. 108: 570a. DOI: 10.1016/j.bpj.2014.11.3119  0.439
2014 Tsai MF, Miller C. Building a temperature-sensitive ion channel. Cell. 158: 977-9. PMID 25171401 DOI: 10.1016/J.Cell.2014.08.008  0.36
2014 Tsai MF, Jiang D, Zhao L, Clapham D, Miller C. Functional reconstitution of the mitochondrial Ca2+/H+ antiporter Letm1. The Journal of General Physiology. 143: 67-73. PMID 24344246 DOI: 10.1085/jgp.201311096  0.518
2014 Tsai M, Miller C. Functional Reconstitution of the Mitochondrial Ca2+/H+ Antiporter Letm1 Biophysical Journal. 106: 428a. DOI: 10.1016/j.bpj.2013.11.2412  0.49
2012 Tsai MF, Fang Y, Miller C. Sided functions of an arginine-agmatine antiporter oriented in liposomes Biochemistry. 51: 1577-1585. PMID 22304019 DOI: 10.1021/Bi201897T  0.331
2012 Chen TY, Tsai MF, Hwang TC. Structures and mechanisms in chloride channels Comprehensive Biophysics. 6: 142-176. DOI: 10.1016/B978-0-12-374920-8.00619-6  0.575
2010 Tsai MF, Jih KY, Shimizu H, Li M, Hwang TC. Optimization of the degenerated interfacial ATP binding site improves the function of disease-related mutant cystic fibrosis transmembrane conductance regulator (CFTR) channels. The Journal of Biological Chemistry. 285: 37663-71. PMID 20861014 DOI: 10.1074/jbc.M110.172817  0.592
2010 Tsai MF, Li M, Hwang TC. Stable ATP binding mediated by a partial NBD dimer of the CFTR chloride channel. The Journal of General Physiology. 135: 399-414. PMID 20421370 DOI: 10.1085/jgp.201010399  0.609
2010 Tsai M, Jih K, Li M, Hwang T. Optimization of the NBD1 Site Improves the Function of G551D-CFTR Channels Biophysical Journal. 98: 321a-322a. DOI: 10.1016/j.bpj.2009.12.1744  0.575
2009 Tsai MF, Shimizu H, Sohma Y, Li M, Hwang TC. State-dependent modulation of CFTR gating by pyrophosphate. The Journal of General Physiology. 133: 405-19. PMID 19332621 DOI: 10.1085/jgp.200810186  0.613
2009 Tsai M, Shimizu H, Soma Y, Li M, Hwang T. Two Distinct Gating Cycles of CFTR Chloride Channels Biophysical Journal. 96: 468a. DOI: 10.1016/J.BPJ.2008.12.2411  0.588
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