Pingna Xu, Ph.D.

Affiliations: 
Biology New York University, New York, NY, United States 
Area:
mutagenesis and carcinogenesis
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"Pingna Xu"

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Suse Broyde grad student 2008 NYU
 (Structural study of a DNA adduct derived from a tumorigenic metabolite of benzo[a]pyrene in high-fidelity and bypass polymerases by computer modeling and molecular dynamics.)
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Publications

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Xu P, Oum L, Lee YC, et al. (2009) Visualizing sequence-governed nucleotide selectivities and mutagenic consequences through a replicative cycle: processing of a bulky carcinogen N2-dG lesion in a Y-family DNA polymerase. Biochemistry. 48: 4677-90
Xu P, Oum L, Geacintov NE, et al. (2008) Nucleotide selectivity opposite a benzo[a]pyrene-derived N2-dG adduct in a Y-family DNA polymerase: a 5'-slippage mechanism. Biochemistry. 47: 2701-9
Xu P, Oum L, Beese LS, et al. (2007) Following an environmental carcinogen N2-dG adduct through replication: elucidating blockage and bypass in a high-fidelity DNA polymerase. Nucleic Acids Research. 35: 4275-88
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