Rajdeep Das, Ph.D.

Computational Biology and Bioinformatics

Mark B. Gerstein	grad student	2003	Yale
(Comprehensive genomic analysis of thermophilic proteins and metabolic enzymes.)

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Das R, Gerstein M. (2004) A method using active-site sequence conservation to find functional shifts in protein families: application to the enzymes of central metabolism, leading to the identification of an anomalous isocitrate dehydrogenase in pathogens. Proteins. 55: 455-63
Savchenko A, Yee A, Khachatryan A, et al. (2003) Strategies for structural proteomics of prokaryotes: Quantifying the advantages of studying orthologous proteins and of using both NMR and X-ray crystallography approaches. Proteins. 50: 392-9
Lin J, Qian J, Greenbaum D, et al. (2002) GeneCensus: genome comparisons in terms of metabolic pathway activity and protein family sharing. Nucleic Acids Research. 30: 4574-82
Das R, Gerstein M. (2002) The stability of thermophilic proteins: a study based on comprehensive genome comparison. Functional & Integrative Genomics. 1: 76-88
Das R, Junker J, Greenbaum D, et al. (2001) Global perspectives on proteins: comparing genomes in terms of folds, pathways and beyond. The Pharmacogenomics Journal. 1: 115-25
Das R, Vothknecht UC. (1999) Phenylalanyl-tRNA synthetase from the archaeon Methanobacterium thermoautotrophicum is an (αβ)2 heterotetrameric protein Biochimie. 81: 1037-1039