William J. Blake, Ph.D.

Affiliations: 
2003 Boston University, Boston, MA, United States 
Area:
Systems Biology, Synthetic Biology
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"William Blake"

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James J. Collins grad student 2003 Boston University
 (Development of artificial gene regulatory networks in Saccharomyces cerevisiae: Genetic switches and noise modulation.)
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Publications

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Phillips EA, Silverman AD, Joneja A, et al. (2023) Detection of viral RNAs at ambient temperature via reporter proteins produced through the target-splinted ligation of DNA probes. Nature Biomedical Engineering
Dymond JS, Richardson SM, Coombes CE, et al. (2011) Synthetic chromosome arms function in yeast and generate phenotypic diversity by design. Nature. 477: 471-6
Blake WJ, Balázsi G, Kohanski MA, et al. (2006) Phenotypic consequences of promoter-mediated transcriptional noise. Molecular Cell. 24: 853-65
Volfson D, Marciniak J, Blake WJ, et al. (2006) Origins of extrinsic variability in eukaryotic gene expression. Nature. 439: 861-4
Blake WJ, Collins JJ. (2005) And the noise played on: stochastic gene expression and HIV-1 infection. Cell. 122: 147-9
Kaern M, Elston TC, Blake WJ, et al. (2005) Stochasticity in gene expression: from theories to phenotypes. Nature Reviews. Genetics. 6: 451-64
Isaacs FJ, Blake WJ, Collins JJ. (2005) Molecular biology. Signal processing in single cells. Science (New York, N.Y.). 307: 1886-8
Blake WJ, Isaacs FJ. (2004) Synthetic biology evolves. Trends in Biotechnology. 22: 321-4
Kaern M, Blake WJ, Collins JJ. (2003) The engineering of gene regulatory networks. Annual Review of Biomedical Engineering. 5: 179-206
Blake WJ, KAErn M, Cantor CR, et al. (2003) Noise in eukaryotic gene expression. Nature. 422: 633-7
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