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David M. MacAlpine

Affiliations: 
Computational Biology and Bioinformatics Duke University, Durham, NC 
Area:
Bioinformatics, Molecular Biology, Computer Science, Genetics
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"David MacAlpine"
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Queying Ding grad student 2011 Duke
Matthew L. Eaton grad student 2011 Duke
Leyna C. DeNapoli grad student 2013 Duke

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Publications

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Chen B, MacAlpine HK, Hartemink AJ, et al. (2023) Spatiotemporal kinetics of CAF-1-dependent chromatin maturation ensures transcription fidelity during S-phase. Genome Research
Chen B, MacAlpine HK, Hartemink AJ, et al. (2023) Spatiotemporal kinetics of CAF-1-dependent chromatin maturation ensures transcription fidelity during S-phase. Biorxiv : the Preprint Server For Biology
Li Y, Hartemink AJ, MacAlpine DM. (2021) Cell-Cycle-Dependent Chromatin Dynamics at Replication Origins. Genes. 12
Hoffman RA, MacAlpine HK, MacAlpine DM. (2021) Disruption of origin chromatin structure by helicase activation in the absence of DNA replication. Genes & Development. 35: 1339-1355
MacAlpine DM. (2021) Stochastic initiation of DNA replication across the human genome. Molecular Cell. 81: 2873-2874
Mitra S, Zhong J, Tran TQ, et al. (2021) RoboCOP: jointly computing chromatin occupancy profiles for numerous factors from chromatin accessibility data. Nucleic Acids Research
Tran TQ, MacAlpine HK, Tripuraneni V, et al. (2021) Linking the dynamics of chromatin occupancy and transcription with predictive models. Genome Research
Tripuraneni V, Memisoglu G, MacAlpine HK, et al. (2021) Local nucleosome dynamics and eviction following a double-strand break are reversible by NHEJ-mediated repair. Genome Research
Mitra S, Zhong J, MacAlpine DM, et al. (2020) RoboCOP: Multivariate State Space Model Integrating Epigenomic Accessibility Data to Elucidate Genome-Wide Chromatin Occupancy. Research in Computational Molecular Biology : ... Annual International Conference, Recomb ... : Proceedings. Recomb (Conference : 2005-). 12074: 136-151
Gutiérrez MP, MacAlpine HK, MacAlpine DM. (2019) Nascent chromatin occupancy profiling reveals locus- and factor-specific chromatin maturation dynamics behind the DNA replication fork. Genome Research
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